Lp⃗−Lq⃗L^{\vec{p}}-L^{\vec{q}} Boundedness of Multiparameter Forelli-Rudin Type Operators on the Product of Unit Balls of Cn\mathbb{C}^n

In this work, we provide a complete characterization of the boundedness of two classes of multiparameter Forelli-Rudin type operators from one mixed-norm Lebesgue space $L^{\vec p}$ to another space $L^{\vec q}$, when $1\leq \vec{p}\leq \vec q<\infty$, equipped with possibly different weights. Using these characterizations, we establish the necessary and sufficient conditions for both $L^{\vec p}-L^{\vec q}$ boundedness of the weighted multiparameter Berezin transform and $L^{\vec p}-A^{\vec q}$ boundedness of the weighted multiparameter Bergman projection, where $A^{\vec q}$ denotes the mixed-norm Bergman space. Our approach presents several novelties. Firstly, we conduct refined integral estimates of holomorphic functions on the unit ball in $\mathbb{C}^n$. Secondly, we adapt the classical Schur's test to different weighted mixed-norm Lebesgue spaces. These improvements are crucial in our proofs and allow us to establish the desired characterization and sharp conditions.Comment: 42 page

SiGeC/Si superlattice microcoolers

Monolithically integrated active cooling is an attractive way for thermal management and temperature stabilization of microelectronic and optoelectronic devices. SiGeC can be lattice matched to Si and is a promising material for integrated coolers. SiGeC/Si superlattice structures were grown on Si substrates by molecular beam epitaxy. Thermal conductivity was measured by the 3omega method. SiGeC/Si superlattice microcoolers with dimensions as small as 40×40 µm^2 were fabricated and characterized. Cooling by as much as 2.8 and 6.9 K was measured at 25 °C and 100 °C, respectively, corresponding to maximum spot cooling power densities on the order of 1000 W/cm^2

Over-expression of HO-1 on mesenchymal stem cells promotes angiogenesis and improves myocardial function in infarcted myocardium

Heme oxygenase-1 (HO-1) is a stress-inducible enzyme with diverse cytoprotective effects, and reported to have an important role in angiogenesis recently. Here we investigated whether HO-1 transduced by mesenchymal stem cells (MSCs) can induce angiogenic effects in infarcted myocardium. HO-1 was transfected into cultured MSCs using an adenoviral vector. 1 × 106 Ad-HO-1-transfected MSCs (HO-1-MSCs) or Ad-Null-transfected MSCs (Null-MSCs) or PBS was respectively injected into rat hearts intramyocardially at 1 h post-myocardial infarction. The results showed that HO-1-MSCs were able to induce stable expression of HO-1 in vitro and in vivo. The capillary density and expression of angiogenic growth factors, VEGF and FGF2 were significantly enhanced in HO-1-MSCs-treated hearts compared with Null-MSCs-treated and PBS-treated hearts. However, the angiogenic effects of HO-1 were abolished by treating the animals with HO inhibitor, zinc protoporphyrin. The myocardial apoptosis was marked reduced with significantly reduced fibrotic area in HO-1-MSCs-treated hearts; Furthermore, the cardiac function and remodeling were also significantly improved in HO-1-MSCs-treated hearts. Our current findings support the premise that HO-1 transduced by MSCs can induce angiogenic effects and improve heart function after acute myocardial infarction

Rheumatoid meningitis: a rare neurological complication of rheumatoid arthritis

ObjectiveTo describe the clinical and neuroimaging characteristics of rheumatoid meningitis (RM) in Chinese patients. MethodsThe patients admitted to our hospital with the diagnosis of RM in the past 8 years were retrospectively analyzed. ResultsSix patients with RM were identified among 933 patients admitted with rheumatoid arthritis (RA). The symptoms of meningitis occurred after onset of arthritis in five patients and before onset in one. Headache (n=6), hyperacute focal neurological deficits (n=4) and seizures (n=3) were the most prevalent symptoms. The nadir modified Rankin Scale score was ≥3 in five patients. Rheumatoid factor was elevated in all patients, and interleukin-6 levels in cerebrospinal fluid were dramatically elevated in three of four tested patients. Magnetic resonance imaging of the brain revealed that the meninges were affected in all patients and the cerebral parenchyma was affected in one patient. The lesions were generally located in the frontoparietal region and showed restricted diffusion along the adjacent subarachnoid space. RM occurred during disease-modifying therapy in four patients. In the acute episode, three patients improved on tocilizumab and the other three improved on pulse corticosteroids. For maintenance therapy, two patients received combined therapy of tocilizumab and other immunosuppressive agents, one received adalimumab and methotrexate, and two received low-dose oral corticosteroids with an immunosuppressive agent. Five patients had a good outcome, and one died of Pneumocystis jirovecii pneumonia after stabilization of his neurologic conditions. No relapse of RM occurred on immunotherapy during follow-up. ConclusionsChinese patients with RM share some remarkable clinical and neuroimaging features and respond well to appropriate immunotherapy. Tocilizumab could be a treatment option for this severe complication of RA

The influence of leader–signaled knowledge hiding on tourism employees’ work withdrawal behavior: A moderated mediating model

Even though organizations encourage the dissemination of knowledge and information among organizational members, the phenomenon of knowledge hiding still exists widely in organizations. The consequences of leader-signaled knowledge hiding are more destructive to the workplace than the consequences of employees’ knowledge hiding. It is particularly necessary to explore the influence mechanism of leader-signaled knowledge hiding on employees’ work behavior. Drawing on Conservation of Resources theory, this study establishes a moderated mediation model with emotional exhaustion as a mediating variable and supervisor-subordinate guanxi as a moderating variable. This study focuses on the consequences of leader-signaled knowledge hiding and divides leader-signaled knowledge hiding into self-practiced knowledge hiding and explicit knowledge hiding. Based on the results of 440 questionnaires from tourism employees, it is shown that leader-signaled knowledge hiding has a positive impact on employees’ work withdrawal behavior. Specifically, leader’s self-practiced knowledge hiding has a greater direct impact on employees’ work withdrawal behavior, while leader’s explicit knowledge hiding has a greater direct impact on employees’ emotional exhaustion. Emotional exhaustion plays a key mediating role in the relationship between leader-signaled knowledge hiding (i.e., self-practiced knowledge hiding and explicit knowledge hiding) and employees’ work withdrawal behavior. Supervisor-subordinate guanxi significantly moderates the positive relationship between leader-signaled knowledge hiding (i.e., self-practiced hiding and explicit knowledge hiding) and employees’ emotional exhaustion. This study is an extension of previous research on knowledge hiding. The results provide a reference for leaders to deal with knowledge hiding and improve organizational knowledge management ability

A Genetic Algorithm Based Multilevel Association Rules Mining for Big Datasets

Multilevel association rules mining is an important domain to discover interesting relations between data elements with multiple levels abstractions. Most of the existing algorithms toward this issue are based on exhausting search methods such as Apriori, and FP-growth. However, when they are applied in the big data applications, those methods will suffer for extreme computational cost in searching association rules. To expedite multilevel association rules searching and avoid the excessive computation, in this paper, we proposed a novel genetic-based method with three key innovations. First, we use the category tree to describe the multilevel application data sets as the domain knowledge. Then, we put forward a special tree encoding schema based on the category tree to build the heuristic multilevel association mining algorithm. As the last part of our design, we proposed the genetic algorithm based on the tree encoding schema that will greatly reduce the association rule search space. The method is especially useful in mining multilevel association rules in big data related applications. We test the proposed method with some big datasets, and the experimental results demonstrate the effectiveness and efficiency of the proposed method in processing big data. Moreover, our results also manifest that the algorithm is fast convergent with a limited termination threshold

Long-term trends in the burden of edentulism in China over three decades: A Joinpoint regression and age-period-cohort analysis based on the global burden of disease study 2019

BackgroundTo investigate secular trends in edentulism incidence, prevalence, and years lived with disability (YLDs) rates in Chinese men and women from 1990 to 2019.MethodsData were obtained from the Global Burden of Disease Study 2019. The annual percentage change and average annual percentage change were calculated using Joinpoint regression analysis. The age-period-cohort (APC) analysis estimated the independent age, period, and cohort effects.ResultsFrom 1990 to 2019, the crude incidence, prevalence, and YLDs of edentulism in the Chinese population increased year by year, while the age-standardized incidence, prevalence, and YLDs decreased, and the latter was higher in women than in men. The APC analysis showed that the age effect increased in men and women from age 20 to 74 and decreased thereafter. The risk of tooth loss increased with age. However, the relationship was not linear. The temporal effect showed a gradual increase; the risk of missing teeth gradually increased with the changing modern living environment. The cohort effect showed a single decreasing trend, with the early birth cohort having a higher risk of tooth loss than the later birth cohort population. The age, period, and cohort effects were consistent for both sexes.ConclusionAlthough the standardized incidence, prevalence, and YLD rate and cohort effect of dentition loss in China are declining, they are still causing a severe burden to China due to the continued aging of the population and the rising period effect. Despite the decreasing trends of the standardized incidence and prevalence of dentition loss and the rate of YLDs, China should develop more effective oral disease prevention and control strategies to reduce the increasing burden of edentulism in the older adult, especially in older women