Light anti-nuclei production in pp collisions at s\sqrt{s}=7 and 14 TeV

A dynamically constrained coalescence model based on the phase space quantization and classical limit method was proposed to investigate the production of light nuclei (anti-nuclei) in non-single diffractive (NSD) pp collisions at $\sqrt{s}$=7 and 14 TeV. This calculation was based on the final hadronic state in the PYTHIA and PACIAE model simulations, the event sample consisted of 1.2$\times 10^8$ events in both simulations. The PACIAE model calculated $\bar D$ yield of 6.247$\times 10^{-5}$ in NSD pp collisions at $\sqrt{s}$=7 TeV is well comparing with the ALICE rough datum of 5.456$\times 10^{-5}$. It indicated the reliability of proposed method in some extent. The yield, transverse momentum distribution, and rapidity distribution of the $\bar D$, $^3{\bar{He}}$, and $_{\bar\Lambda} ^3{\bar H}$ in NSD pp collisions at $\sqrt{s}$=7 and 14 TeV were predicted by PACIAE and PYTHIA model simulations. The yield resulted from PACIAE model simulations is larger than the one from PYTHIA model. This might reflect the role played by the parton and hadron rescatterings.Comment: 5 pages, 2 figure

口服雄黄治疗骨髓增生异常综合征概况

Chinese arsenic drugs have been applied in Chinese medicine for several centuries. Active ingredients of realgar is As2S2. Oral realgar has been widely used in the treatment of myelodysplastic syndrome (MDS) with obvious Chinese characteristics, and the good clinical outcomes have been achieved. Decreasing the gastrointestinal adverse reactions of realgar can not only increase tolerance of patient to realgar, but improve the clinical efficacy, which will ensure the safety of oral realgar for clinical use, as well as open a new vision for the treatment of MDS.含砷中药在祖国传统医学中有悠久的历史。雄黄的活性成分是二硫化二砷（As2S2）。口服雄黄在骨髓增生异常综合征（MDS）的临床治疗中越来越广泛，具有明显的中医特色，也取得了很好的临床效果。控制雄黄的消化道不良反应，不仅增加患者对口服雄黄的耐受性，而且可以提高临床疗效，为口服雄黄的临床应用提供了安全性，也为MDS的治疗领域开辟了新途径

An Efficient Process for Pretreatment of Lignocelluloses in Functional Ionic Liquids

Background and Aims. The complex structure of the lignocelluloses is the main obstacle in the conversion of lignocellulosic biomass into valuable products. Ionic liquids provide the opportunities for their efficient pretreatment for biomass. Therefore, in this work, pretreatment of corn stalk was carried out in ultrasonic-assisted ionic liquid including 1-butyl-3-methylimidazolium chloride [BMIM]Cl, 1-H-3-methylimidazolium chloride [HMIM]Cl, and 1-(1-propylsulfonic)-3-imidazolium chloride [HSO3-pMIM]Cl at 70°C for 2 h. We compared the pretreatments by ionic liquid with and without the addition of deionized water. Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were employed to analyze the chemical characteristics of regenerated cellulose-rich materials. Results. [HMIM]Cl and [HSO3-pMIM]Cl were effective in lignin extraction to obtain cellulose-rich materials. FTIR analysis and SEM analysis indicated the effective lignin removal and the reduced crystallinity of cellulose-rich materials. Enzymatic hydrolysis of cellulose-rich materials was performed efficiently. High yields of reducing sugar and glucose were obtained when the corn stalk was pretreated by [HMIM]Cl and [HSO3-pMIM]Cl. Conclusions. Ionic liquids provided the ideal environment for lignin extraction and enzymatic hydrolysis of corn stalk and [HMIM]Cl and [HSO3-pMIM]Cl proved the most efficient ionic liquids. This simple and environmentally acceptable method has a great potential for the preparation of bioethanol for industrial production

Perspective on Therapeutic Strategies of Leukemia Treatment — Focus on Arsenic Compounds

Leukemia is a type of cancer of the body’s blood-forming tissues, including the bone marrow and the lymphatic system. Treatments for leukemia are complex, depending upon the type of leukemia and other factors. Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) and accounts for approximately 10-15% of all cases of AML in adults. Arsenic and its compounds are widely distributed in the environment and have been used medicinally for over 2,000 years. In fact, investigators from China and the USA have demonstrated that treatment with ATO (As2O3, AsIII) results in complete remission in 90% of relapsed APL patients since mid-1990s. Moreover, As2S2 or As4S4, also known as realgar, has been gaining increasing attention and is traditionally used to treat certain types of hematological disorders including chronic myeloid leukemia (CML), AML, myelodysplastic syndrome (MDS) and MDS/AML in China. In this chapter, we first highlight the pharmacokinetics of ATO and realgar in leukemia patients and/or healthy volunteer. We will further summarize the detailed mechanisms underlying the cytocidal effects of these arsenic compounds. We also provide detailed insight into potential future clinical application of those promising candidates endowed with potent antitumor activities in view of combination with arsenic compounds

急性曼陀罗中毒患者临床护理观察

Mandala is used medicinally to treat cough and asthma, conscious sedation. Entire individual plant is poisonous, and the toxic substances are hyoscyamine and scopolamine and atropine, etc. It is a rare case that patients were poisoned by Mandala in clinical practice. More reports were about the cases that patients were poisoned by seeds, fruit, leaf and flower. The toxicity would stimulate and restrain the central nervous system successively, block the reactions of acetylcholine, resist and paralyze the parasympathetic nerve. The paper discusses continuous blood purification treatment and clinical nursing of mandala poisoning patients by case analysis.曼陀罗内服可用来平喘止咳，镇静麻醉。曼陀罗全株有毒，毒性物质为莨菪碱、东莨菪碱和阿托品等。在临床中遇到的曼陀罗中毒罕见。有病例报道多为误食曼陀罗种子、果实、叶、花所致，其毒性作用是对中枢神经先兴奋后抑制，阻断乙酰胆碱反应，对抗和麻痹副交感神经。本文通过病例分析，探讨如何对曼陀罗中毒患者行连续性血液净化治疗、临床护理