365 research outputs found
An Angular Position-Based Two-Stage Friction Modeling and Compensation Method for RV Transmission System
In RV transmission system (RVTS), friction is closely related to rotational speed and angular position. However, classical friction models do not consider the influence of angular position on friction, resulting in limited accuracy in describing the RVTS frictional behavior. For this reason, this paper proposes an angular position-based two-stage friction model for RVTS, and achieves a more accurate representation of friction of RVTS. The proposed model consists of two parts, namely pre-sliding model and sliding model, which are divided by the maximum elastic deformation recovery angle of RVTS obtained from loading-unloading tests. The pre-sliding friction behavior is regarded as a spring model, whose stiffness is determined by the angular position and the acceleration when the velocity crosses zero, while the sliding friction model is established by the angular-segmented Stribeck function, and the friction parameters of the adjacent segment are linearly smoothed. A feedforward compensation based on the proposed model was performed on the RVTS, and its control performance was compared with that using the classical Stribeck model. The comparison results show that when using the proposed friction model, the low-speed-motion smoothness of the RVTS can be improved by 14.2%, and the maximum zero-crossing speed error can be reduced by 37.5%, which verifies the validity of the proposed friction model, as well as the compensation method
Traditional Chinese Medicine syndrome patterns and Qi-regulating, chest-relaxing and blood-activating therapy on cardiac syndrome X
AbstractObjectiveTo master the syndrome patterns characteristics and explore the effective therapy methods of Traditional Chinese Medicine (TCM) for cardiac syndrome X (CSX).MethodsThe TCM syndrome characteristics were mastered and the TCM intervention programs were determined by clinical investigations for TCM syndrome patterns characteristics of CSX patients. Then, the clinical efficacy studies on TCM intervention for CSX were carried out through randomized controlled trials.ResultsCSX is a clinical syndrome with the main manifestations of chest pain and chest stuffiness, and Qi stagnation, phlegm retention and blood stasis are the basic symptoms of CSX. As a result, the Qi-regulating, chest-relaxing and blood-activating therapy integrated with some Western Medicines was adopted for treatment. The effect of Qi-regulating, chest-relaxing and blood-activating therapy can reduce the frequency and degree of angina, improve the symptoms and exercise the tolerance of patients, inhibit the inflammatory response of vascular walls and protect the function of vascular endothelial cells, which is better than that of the simple and conventional Western Medicine alone.ConclusionA good effect was achieved in the integration of Chinese and Western Medicines for CSX. The therapy is worthy to be applied further in clinical practice. On the other hand, more long-term and randomised controlled studies with large samples are still required to further determine the clinical efficacy and safety of the therapy
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Extension of summer (June–August) temperature records for northern Inner Mongolia (1715–2008), China using tree rings
This paper presents a spatially and temporally improved reconstruction of mean summer (June–August) temperature derived from tree-ring width data of Dahurian larch (Larix gmelinii Rupr.) from the northern Great Xing'an Mountains, Northeast China. Three new chronologies were added to the original 2011 reconstruction, and the reconstruction extended back to AD 1715. The reconstruction was generated using a simple linear regression method, verified by independent meteorological data, and accounts for 47.0% of the actual temperature variance during the common period (1957–2008). The reconstruction captures decadal and century-scale regional temperature variability, such as cold decades (1940s, 1930s, 1790s, 1950s and 1850s), warm decades (2000s, 1870s, 1750s, 1980s and 1840s), a cold half-century (ca. 1750–1799), and a warm half-century (ca. 1900–1949). It also reveals slightly higher frequency of cold years (20.4%) than warm years (18.0%), and a recent warming trend. Compared to the original 2011 reconstruction, this reconstruction has lower inter-annual temperature variability, high explained variance and high representativeness of regional climate. The reconstruction also correlates with the East Asian Monsoon and the Pacific Ocean signals, and indicates the feasibility of using tree rings from high latitude Northeast China to reconstruct summer temperature in permafrost forest environments
Response of radial growth to warming and CO2 enrichment in southern Northeast China: a case of Pinus tabulaeformis
The southern part of northeast China has experienced a marked warming and drying climate. We provide dendrochronological evidence for atmospheric CO2 fertilization and the impacts of warming on Chinese pine (Pinus tabulaeformis) growth. The results of this study show that increased temperature has a negative effect on pine growth during a major part of the growing season and a weakly positive effects on growth during the remaining portion of the year. The monthly temperatures explain ca. 20 % of the total variance in the annual radial growth of Chinese pine from 1901 to 2009. An increase of approximately 3–5 °C is the maximum that Chinese pine can tolerate in this region with an annual rainfall of 500–700 mm. Our results suggest a that there is a proportional response to warming only up to a maximum of 1 °C warming, and indicate the complexities of succession in forest ecosystems in terms of adaptation and evolution in local pine populations under a rapid warming condition. In addition, increasing atmospheric CO2 concentrations have a positive effect on tree growth. This effect can be detected with conventional dendrochronological methods
Heat Transfer Correlations for Supercritical Water in Vertically Upward Tubes
Supercritical pressure water (SCW) has been widely used in many engineering fields and industries, such as fossil fuel-fired power plants, newly developed Gen-IV nuclear power plants and so forth. Heat transfer characteristics of SCW are of great importance for both design and safe operation of the related systems. Many heat transfer correlations have been developed in the history for predicting the heat transfer characteristics of SCW. However, the prediction accuracy of the existing correlations is less than satisfactory, especially in the cases with deteriorated heat transfer (DHT) because of the severe and quick variation in thermal physical properties of SCW in the vicinity of the fluids’ pseudo critical point. It is very necessary to develop new correlations for the heat transfer of SCW to meet the engineering requirements for satisfactory prediction of the heat transfer behavior of SCW. In this chapter, experimental data on heat transfer of SCW are extensively collected from published literatures, and the performance of the existing heat transfer correlations for SCW are reviewed and quantitatively evaluated against the collected experimental data, and then a new heat transfer correlation for SCW with high prediction accuracy is proposed
Critical closing pressure as a new hemodynamic marker of cerebral small vessel diseases burden
PurposeTo investigate cerebrovascular hemodynamics, including critical closing pressure (CrCP) and pulsatility index (PI), and their independent relationship with cerebral small vessel disease (CSVD) burden in patients with small-vessel occlusion (SVO).MethodsWe recruited consecutive patients with SVO of acute cerebral infarction who underwent brain magnetic resonance imaging (MRI), transcranial Doppler (TCD) and CrCP during admission. Cerebrovascular hemodynamics were assessed using TCD. We used the CSVD score to rate the total MRI burden of CSVD. Multiple regression analysis was used to determine parameters related to CSVD burden or CrCP.ResultsNinety-seven of 120 patients (mean age, 64.51 ± 9.99 years; 76% male) completed the full evaluations in this study. We observed that CrCP was an independent determinant of CSVD burden in four models [odds ratio, 1.41; 95% confidence interval (CI), 1.17–1.71; P < 0.001] and correlated with CSVD burden [β (95% CI): 0.05 (0.04–0.06); P < 0.001]. In ROC analysis, CrCP was considered as a predictor of CSVD burden, and AUC was 86.2% (95% CI, 78.6–93.9%; P < 0.001). Multiple linear regression analysis showed that CrCP was significantly correlated with age [β (95% CI): 0.27 (0.06 to 0.47); P = 0.012], BMI [β (95% CI): 0.61 (0.00–1.22)] and systolic BP [β (95% CI): 0.16 (0.09–0.23); P < 0.001].ConclusionsCrCP representing cerebrovascular tension is an independent determinant and predictor of CSVD burden. It was significantly correlated with age, BMI and systolic blood pressure. These results provide new insights in the mechanism of CSVD development
Effect of Nitrogen Addition on Selection of Germination Trait in an Alpine Meadow on the Tibet Plateau
Seed germination requirements may determine the kinds of habitat in which plants can survive. We tested the hypothesis that nitrogen (N) addition can change seed germination trait-environmental filter interactions and ultimately redistribute seed germination traits in alpine meadows. We determined the role of N addition on germination trait selection in an alpine meadow after N addition by combining a 3-year N addition experiment in an alpine meadow and laboratory germination experiments. At the species level, germination percentage, germination rate (speed) and breadth of temperature niche for germination (BTN) were positively related to survival of a species in the fertilized community. In addition, community-weighted means of germination percentage, germination rate, germination response to alternating temperature and BTN increased. However, germination response to wet-cold storage (cold stratification) and functional richness of germination traits was lower in alpine meadows with high-nitrogen addition than in those with no, low and medium N addition. Thus, N addition had a significant influence on environmental filter-germination trait interactions and generated a different set of germination traits in the alpine meadow. Further, the effect of N addition on germination trait selection by environmental filters was amount-dependent. Low and medium levels of N addition had less effect on redistribution of germination traits than the high level
USP6-associated soft tissue tumors with bone metaplasia: Clinicopathologic and genetic analysis and the identification of novel USP6 fusion partners
IntroductionAmong those tumors with consistent USP6 rearrangement, some arise from soft tissue and show bone metaplasia, including myositis ossificans (MO), fibro-osseous pseudotumor of digits (FOPD), soft tissue aneurysmal bone cyst (ST-ABC) and fasciitis ossificans (FO). These lesions are easily confused with malignancies because they show a rapid growth rate and brisk mitoses. Here, we aim to clarify the clinicopathologic and genetic characteristics of this entity and analyze the correlations among the different subtypes in one of the largest cohorts.Materials and MethodsThe clinicopathologic features of 73 cases of MO, FOPD, ST-ABC and FO diagnosed at West China Hospital, Sichuan University from January 2010 to December 2021 were retrospectively analyzed. Forty-three undecalcified samples were analyzed by systematic genetic studies, including fluorescence in situ hybridization (FISH), reverse transcription polymerase chain reaction (RT-PCR), Sanger sequencing and next-generation-based sequencing were performed.ResultsThis series included 40 males and 33 females aged 2 to 80 years old (median: 31 years). FOPD occurred in extremal soft tissue, while lower extremities (38/58, 65.5%) were the most commonly involved lesions in the other three subgroups. Histologically, proliferative myofibroblasts/fibroblasts with varying degrees of osteoid tissue were present. Fluorescence in situ hybridization (FISH) results indicated that 22 cases (22/27, 81.5%) were positive for USP6 rearrangement, and 5 cases were negative. Among those cases with positive FISH results, 18 underwent reverse transcription-polymerase chain reaction (RT-PCR) detection that successfully detected common USP6 fusion types. Thirteen cases showed COL1A1::USP6 fusion, one showed MYH9::USP6 fusion, and 4 were negative for common fusion types. Next-generation-based sequencing technology was performed on two lesions with negative RT–PCR results and novel fusion partners SNHG3 and UBE2G1 were discovered.ConclusionsOur findings revealed that COL1A1 is the most common fusion partner in this entity, unlike primary aneurysmal bone cysts and nodular fasciitis. Notably, we believed that FO may demonstrate more similar clinicopathologic and genetic manifestations with MO/FOPD and ST-ABC instead of nodular fasciitis for involving lower limbs most frequently and showing recurrent COL1A1::USP6 fusion. Additionally, this study also found two novel USP6 fusion partners, which further expanded our knowledge of this neoplastic spectrum
Quick Identification of ABC Trilayer Graphene at Nanoscale Resolution via a Near-field Optical Route
ABC-stacked trilayer graphene has exhibited a variety of correlated phenomena
owing to its relatively flat bands and gate-tunable bandgap. However,
convenient methods are still lacking for identifying ABC graphene with
nanometer-scale resolution. Here we demonstrate that the scanning near-field
optical microscope (SNOM) working in ambient conditions can provide quick
recognition of ABC trilayer graphene with no ambiguity and excellent resolution
(~20 nm). The recognition is based on the difference in their near-field
infrared (IR) responses between the ABA and ABC trilayers. We show that in most
frequencies, the response of the ABC trilayer is weaker than the ABA trilayer.
However, near the graphene phonon frequency (~1585 cm-1), ABC's response
increases dramatically when gated and exhibits a narrow and sharp Fano-shape
resonant line, whereas the ABA trilayer is largely featherless. Consequently,
the IR contrast between ABC and ABA becomes reversed and can even be striking
(ABC/ABA~3) near the graphene phonon frequency. The observed near-field IR
features can serve as a golden rule to quickly distinguish ABA and ABC
trilayers with no ambiguity, which could largely advance the exploration of
correlation physics in ABC-stacked trilayer graphene
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