Adaptation in face animacy perception:An event-related potential study

A real face differs from an artificial face mainly in the animacy. Nowadays, the perception boundaries between the real and artificial faces are becoming blurred in our life with the ubiquitous use of AI. Therefore, the perception of animacy causes increasing interests. Here, we used an adaptation paradigm to investigate the animacy perception in faces. We morphed a real and an artificial face to generate a continuum of face images, and asked participants to judge the animacy of those face images after they were exposed to a real face or an artificial face. We found that after adaptation to a real face, the subjects were apt to identify a subsequently ambiguous face to be inanimate, whereas after adaptation to an artificial face, the subjects were apt to identify a subsequently ambiguous face to be animate, i.e., the face animacy aftereffect (FAAE). We simultaneously recorded EEG during the task and analyzed the event-related potentials in response to the test faces, and found that adaptation to a face animacy suppressed the amplitude of LPP (late positive potential) and prolonged the latencies of N250r and LPP, in response to subsequent animacy-congruent faces. However, for subsequent animacy-incongruent faces, the amplitude was enhanced in LPP and the latencies were shortened in N250r and LPP. Those modulations of N250r and LPP activity act as a neural correlate of face animacy adaptation

Clinical characteristics and survival analysis in critical and non-critical patients with COVID-19 in Wuhan, China: a single-center retrospective case control study

Since the outbreak of COVID-19 in China at the end of 2019, the world has experienced a large-scale epidemic caused by the SARS-CoV-2. The epidemiological and clinical course of COVID-19 patients has been reported, but there have been few analyses about the characteristics, predictive risk factors, and outcomes of critical patients. In this single-center retrospective case–control study, 90 adult inpatients hospitalized at Tongji Hospital (Wuhan, China) were included. Demographic, clinical, laboratory tests, and treatment data were obtained and compared between critical and non-critical patients. We found that compared with non-critical patients, the critical patients had higher SOFA score and qSOFA scores. Critical patients had lower lymphocyte and platelet count, elevated D-dimer, decreased fibrinogen, and elevated high-sensitivity C-reactive protein (hsCRP), and interleukin-6(IL-6). More critical patients received treatment including antibiotics, anticoagulation, corticosteroid, and oxygen therapy than non-critical ones. Multivariable regression showed higher qSOFA score and elevation of IL-6 were related to critical patients. Antibiotic usage and anticoagulation were associated with decreased in-hospital mortality. And critical grouping contributed greatly to in-hospital death. Critical COVID-19 patients have a more severe clinical course. qSOFA score and elevation of IL-6 are risk factors for critical condition. Non-critical grouping, positive antibiotic application, and anticoagulation may be beneficial for patient survival