A non-equilibrium dynamic mechanism for the allosteric effect

Allosteric regulation is often viewed as thermodynamic in nature. However protein internal motions during an enzymatic reaction cycle can be slow hopping processes over numerous potential barriers. We propose that regulating molecules may function by modifying the nonequilibrium protein dynamics. The theory predicts that an enzyme under the new mechanism has different temperature dependence, waiting time distribution of the turnover cycle, and dynamic fluctuation patterns with and without effector. Experimental tests of the theory are proposed.Comment: accepted by Phys. Rev. Lett. Major revisions were made to fit the style. 4 pages, 2 figure

The Importance of Proper Renormalization Scale-Setting for Testing QCD at Colliders

A primary problem for perturbative QCD analyses is how to set the renormalization scale of the QCD running coupling in order to achieve maximally precise fixed-order predictions for physical observables. The Principle of Maximum Conformality (PMC) eliminates the ambiguities associated with the conventional renormalization scale-setting procedure, giving predictions which are independent of the choice of renormalization scheme. The scales of the QCD couplings and the effective number of quark flavors are set order by order in the pQCD series. The PMC has a solid theoretical foundation, satisfying the standard renormalization group invariance and all of the the self-consistency conditions derived from the renormalization group......In this brief report, we summarize the results of our recent PMC applications for a number of collider processes, emphasizing their generality and applicability....... These results demonstrate that the application of the PMC systematically eliminates a major theoretical uncertainty for pQCD predictions, thus increasing the sensitivity of the colliders to possible new physics beyond the Standard Model.Comment: 10 pages, 4 figures. The title has been changed. This review, submitted to Frontiers of Physics, is based on a contribution by S.J.B. at the Conference {\it Workshop on Physics at a Future High Intensity Collider @ 2-7 GeV in China} Hefei, China January 14-16, 201

Spatial organization and evolutional period of the epidemic model using cellular automata

We investigate epidemic models with spatial structure based on the cellular automata method. The construction of the cellular automata is from the study by Weimar and Boon about the reaction-diffusion equations [Phys. Rev. E 49, 1749 (1994)]. Our results show that the spatial epidemic models exhibit the spontaneous formation of irregular spiral waves at large scales within the domain of chaos. Moreover, the irregular spiral waves grow stably. The system also shows a spatial period-2 structure at one dimension outside the domain of chaos. It is interesting that the spatial period-2 structure will break and transform into a spatial synchronous configuration in the domain of chaos. Our results confirm that populations embed and disperse more stably in space than they do in nonspatial counterparts.Comment: 6 papges,5 figures. published in Physics Review

Eliminating the Renormalization Scale Ambiguity for Top-Pair Production Using the Principle of Maximum Conformality

It is conventional to choose a typical momentum transfer of the process as the renormalization scale and take an arbitrary range to estimate the uncertainty in the QCD prediction. However, predictions using this procedure depend on the renormalization scheme, leave a non-convergent renormalon perturbative series, and moreover, one obtains incorrect results when applied to QED processes. In contrast, if one fixes the renormalization scale using the Principle of Maximum Conformality (PMC), all non-conformal $\{\beta_i\}$-terms in the perturbative expansion series are summed into the running coupling, and one obtains a unique, scale-fixed, scheme-independent prediction at any finite order. The PMC scale $\mu^{\rm PMC}_R$ and the resulting finite-order PMC prediction are both to high accuracy independent of the choice of initial renormalization scale $\mu^{\rm init}_R$, consistent with renormalization group invariance. As an application, we apply the PMC procedure to obtain NNLO predictions for the $t\bar{t}$-pair production at the Tevatron and LHC colliders. The PMC prediction for the total cross-section $\sigma_{t\bar{t}}$ agrees well with the present Tevatron and LHC data. We also verify that the initial scale-independence of the PMC prediction is satisfied to high accuracy at the NNLO level: the total cross-section remains almost unchanged even when taking very disparate initial scales $\mu^{\rm init}_R$ equal to $m_t$, $20\,m_t$, $\sqrt{s}$. Moreover, after PMC scale setting, we obtain $A_{FB}^{t\bar{t}} \simeq 12.5$, $A_{FB}^{p\bar{p}} \simeq 8.28$ and $A_{FB}^{t\bar{t}}(M_{t\bar{t}}>450 \;{\rm GeV}) \simeq 35.0$. These predictions have a $1\,\sigma$-deviation from the present CDF and D0 measurements; the large discrepancy of the top quark forward-backward asymmetry between the Standard Model estimate and the data are thus greatly reduced.Comment: 4 pages. Detailed derivations for the top-quark pair total cross-sections and forward-backward asymmetry can be found in Refs.[arXiv:1204.1405; arXiv:1205.1232]. To match the published version. To be published in Phys.Rev.Let