27 research outputs found
Object-Oriented Scale-Adaptive Filtering for human detection from stereo images
No full text2004 IEEE Conference on Cybernetics and Intelligent Systems135-14
Indium gallium nitride on silicon heterojunction Schottky barrier solar cell characteristics
No full textMetabolomic Analysis of the Urine from Rats with Collagen-Induced Arthritis with the Effective Part of Caulophyllum robustum Maxim
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Joining of Broken Multiwalled Carbon Nanotubes Using an Electron Beam-Induced Deposition (EBID) Technique
No full textSynthesis of novel intumescent flame retardant containing phosphorus, nitrogen and boron and its application in polyethylene
No full textMulticomponent Approach to the Synthesis of Oxidized Amides through Nitrile Hydrozirconation
No full textAntagomir-1290 suppresses CD133+ cells in non-small cell lung cancer by targeting fyn-related Src family tyrosine kinase
No full textCancer stem-like cells (CSLCs) are involved in cancer initiation, development, and metastasis, and microRNAs (miRNAs) play pivotal roles in regulating CSLCs. miRNA-based therapeutic strategy associated with CSLCs might promise potential new therapeutic approaches. In the present study, we found that miR-1290 was increased in CD133+ cells. Antagomir-1290 significantly suppressed tumor volume and weight initiated by CD133+ cells in vivo. Furthermore, antagomir-1290 significantly inhibited the proliferation, clonogenicity, invasion, and migration of CD133+ cells by targeting fyn-related Src family tyrosine kinase. These findings provide insights into the clinical prospect of miR-1290-based therapies for non-small cell lung cancer
