21 research outputs found
Differential equations and conformal structures
We provide five examples of conformal geometries which are naturally
associated with ordinary differential equations (ODEs). The first example
describes a one-to-one correspondence between the Wuenschmann class of 3rd
order ODEs considered modulo contact transformations of variables and (local)
3-dimensional conformal Lorentzian geometries. The second example shows that
every point equivalent class of 3rd order ODEs satisfying the Wuenschmann and
the Cartan conditions define a 3-dimensional Lorentzian Einstein-Weyl geometry.
The third example associates to each point equivalence class of 3rd order ODEs
a 6-dimensional conformal geometry of neutral signature. The fourth example
exhibits the one-to-one correspondence between point equivalent classes of 2nd
order ODEs and 4-dimensional conformal Fefferman-like metrics of neutral
signature. The fifth example shows the correspondence between undetermined ODEs
of the Monge type and conformal geometries of signature . The Cartan
normal conformal connection for these geometries is reducible to the Cartan
connection with values in the Lie algebra of the noncompact form of the
exceptional group . All the examples are deeply rooted in Elie Cartan's
works on exterior differential systems.Comment: Some typos in formulae concerning (3,2)-signature conformal metrics
of Section 5.3 were correcte
Characterization of a Peptide Domain within the GB Virus C NS5A Phosphoprotein that Inhibits HIV Replication
BACKGROUND:GBV-C infection is associated with prolonged survival in HIV-infected people and GBV-C inhibits HIV replication in co-infection models. Expression of the GBV-C nonstructural phosphoprotein 5A (NS5A) decreases surface levels of the HIV co-receptor CXCR4, induces the release of SDF-1 and inhibits HIV replication in Jurkat CD4+ T cell lines. METHODOLOGY/PRINCIPAL FINDINGS:Jurkat cell lines stably expressing NS5A protein and peptides were generated and HIV replication in these cell lines assessed. HIV replication was significantly inhibited in all cell lines expressing NS5A amino acids 152-165. Substitution of an either alanine or glycine for the serine at position 158 (S158A or S158G) resulted in a significant decrease in the HIV inhibitory effect. In contrast, substituting a phosphomimetic amino acid (glutamic acid; S158E) inhibited HIV as well as the parent peptide. HIV inhibition was associated with lower levels of surface expression of the HIV co-receptor CXCR4 and increased release of the CXCR4 ligand, SDF-1 compared to control cells. Incubation of CD4+ T cell lines with synthetic peptides containing amino acids 152-167 or the S158E mutant peptide prior to HIV infection resulted in HIV replication inhibition compared to control peptides. CONCLUSIONS/SIGNIFICANCE:Expression of GBV-C NS5A amino acids 152-165 are sufficient to inhibit HIV replication in vitro, and the serine at position 158 appears important for this effect through either phosphorylation or structural changes in this peptide. The addition of synthetic peptides containing 152-167 or the S158E substitution to Jurkat cells resulted in HIV replication inhibition in vitro. These data suggest that GBV-C peptides or a peptide mimetic may offer a novel, cellular-based approach to antiretroviral therapy
Männlichkeitskonstruktionen jüdischer Häftlinge in NS-Konzentrationslagern
Inside the Nazi concentration camps Jewish prisoners experienced extreme forms of exclusion, humiliation and violence. Disqualified as the “countertype” of the “Aryan” man, they were denied not only their participation in the “national community” but also their male dignity. This paper looks at various attempts of Jewish prisoners to preserve and assert their gendered identities in the face of terror by analysing three different manifestations of masculinity to be found in autobiographical sources: the ideal of the revolutionary fighter for the class struggle, the ideal of the emancipated “Bildungsbürger” and patriarch, and finally the ideal of the soldier internalised through Jewish men’s active participation in the German wars
Jüdische politische Häftlinge im frühen KZ Dachau: Widerstand, Verfolgung und antisemitisches Feindbild
No description supplie
"NatĂĽrlich weiĂź ich, wer mich ins KZ gebracht hat und warum..." - Die Inhaftierung von Juden im Konzentrationslager Osthofen 1933/34
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Explosivepidemie Worbis 1972 Beitrag zur Epidemiologie der E-Ruhr
Informationszentrum Sozialwissenschaften, Berlin, B 2211- GL 98 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman
Untersuchungen zur Kompostierbarkeit von Reststoffen der Papierindustrie und Altpapier unter besonderer Beruecksichtigung von Schadstoffbilanzierungen
Available from TIB Hannover: RN 7868(104) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman