1,051 research outputs found
Elastic Decision Transformer
This paper introduces Elastic Decision Transformer (EDT), a significant
advancement over the existing Decision Transformer (DT) and its variants.
Although DT purports to generate an optimal trajectory, empirical evidence
suggests it struggles with trajectory stitching, a process involving the
generation of an optimal or near-optimal trajectory from the best parts of a
set of sub-optimal trajectories. The proposed EDT differentiates itself by
facilitating trajectory stitching during action inference at test time,
achieved by adjusting the history length maintained in DT. Further, the EDT
optimizes the trajectory by retaining a longer history when the previous
trajectory is optimal and a shorter one when it is sub-optimal, enabling it to
"stitch" with a more optimal trajectory. Extensive experimentation demonstrates
EDT's ability to bridge the performance gap between DT-based and Q
Learning-based approaches. In particular, the EDT outperforms Q Learning-based
methods in a multi-task regime on the D4RL locomotion benchmark and Atari
games. Videos are available at: https://kristery.github.io/edt/Comment: https://kristery.github.io/edt
Learning Generalizable Dexterous Manipulation from Human Grasp Affordance
Dexterous manipulation with a multi-finger hand is one of the most
challenging problems in robotics. While recent progress in imitation learning
has largely improved the sample efficiency compared to Reinforcement Learning,
the learned policy can hardly generalize to manipulate novel objects, given
limited expert demonstrations. In this paper, we propose to learn dexterous
manipulation using large-scale demonstrations with diverse 3D objects in a
category, which are generated from a human grasp affordance model. This
generalizes the policy to novel object instances within the same category. To
train the policy, we propose a novel imitation learning objective jointly with
a geometric representation learning objective using our demonstrations. By
experimenting with relocating diverse objects in simulation, we show that our
approach outperforms baselines with a large margin when manipulating novel
objects. We also ablate the importance on 3D object representation learning for
manipulation. We include videos, code, and additional information on the
project website - https://kristery.github.io/ILAD/ .Comment: project page: https://kristery.github.io/ILAD
The role of thrombomodulin lectin-like domain in inflammation
Thrombomodulin (TM) is a cell surface glycoprotein which is widely expressed in a variety of cell types. It is a cofactor for thrombin binding that mediates protein C activation and inhibits thrombin activity. In addition to its anticoagulant activity, recent evidence has revealed that TM, especially its lectin-like domain, has potent anti-inflammatory function through a variety of molecular mechanisms. The lectin-like domain of TM plays an important role in suppressing inflammation independent of the TM anticoagulant activity. This article makes an extensive review of the role of TM in inflammation. The molecular targets of TM lectin-like domain have also been elucidated. Recombinant TM protein, especially the TM lectin-like domain may play a promising role in the management of sepsis, glomerulonephritis and arthritis. These data demonstrated the potential therapeutic role of TM in the treatment of inflammatory diseases
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