2,980 research outputs found
Entanglement reciprocation using three level atoms in a lambda configuration
We propose a scheme in which entanglement can be transferred from atoms
(discrete variables) to entangled states of cavity fields (continuous
variables). The cavities play the role of a kind of quantum memory for
entanglement, in such a way that it is possible to retrieve it back to the
atoms. In our method, two three level atoms in a lambda configuration,
previously entangled, are set to interact with single mode cavity fields
prepared in coherent states. During the process, one e-bit of entanglement may
be deposited in the cavities in an efficient way. We also show that the stored
entanglement may be transferred back to flying atoms
Reply to Itin, Obukhov and Hehl paper "An Electric Charge has no Screw Sense - A Comment on the Twist-Free Formulation of Electrodynamics by da Rocha & Rodrigues"
In this note we briefly comment a paper by Itin, Obukhov and Hehl criticising
our previous paper. We show that all remarks by our critics are ill conceived
or irrelevant to our approach and moreover we provide some pertinent new
comments to their critical paper, with the aim to clarify even more our view on
the subject.Comment: This paper is a reply to arXiv:0911.5175 [physics.class-ph] which
made some criticisms on our paper "Pair and Impar, Even and Odd Form Fields
and Electromagnetism" arXiv:0811.1713 [math-ph] to appear in Annalen der
Physik. A short version of our reply will also appear in Annalen de Physi
New results for the two neutrino double beta decay in deformed nuclei with angular momentum projected basis
Four nuclei which are proved to be emitters (Ge,
Se, Nd, U), and four suspected, due to the corresponding
Q-values, to have this property (Nd, Sm, Gd,
Th), were treated within a proton-neutron quasiparticle random phase
approximation (pnQRPA) with a projected spherical single particle basis. The
advantage of the present procedure over the ones using a deformed Woods Saxon
or Nilsson single particle basis is that the actual pnQRPA states have a
definite angular momentum while all the others provide states having only K as
a good quantum number. The model Hamiltonian involves a mean field term
yielding the projected single particle states, a pairing interaction for alike
nucleons and a dipole-dipole proton-neutron interaction in both the
particle-hole (ph) and particle-particle (pp) channels. The effect of nuclear
deformation on the single beta strength distribution as well as on the double
beta Gamow-Teller transition amplitude (M) is analyzed. The
results are compared with the existent data and with the results from a
different approach, in terms of the process half life T. The case of
different deformations for mother and daughter nuclei is also presented.Comment: 45 pages, 13 figure
Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs
peer-reviewedBackground:
Carotid body (peripheral oxygen sensor) sensitisation is pivotal in the development of chronic intermittent hypoxia (CIH)-induced hypertension. We sought to determine if exposure to CIH, modelling human sleep apnoea, adversely affects cardiorespiratory control in guinea-pigs, a species with hypoxia-insensitive carotid bodies. We reasoned that CIH-induced disruption of gut microbiota would evoke cardiorespiratory morbidity.
Methods:
Adult male guinea-pigs were exposed to CIH (6.5% O2 at nadir, 6 cycles.hour−1) for 8 h.day−1 for 12 consecutive days.
Findings:
CIH-exposed animals established reduced faecal microbiota species richness, with increased relative abundance of Bacteroidetes and reduced relative abundance of Firmicutes bacteria. Urinary corticosterone and noradrenaline levels were unchanged in CIH-exposed animals, but brainstem noradrenaline concentrations were lower compared with sham. Baseline ventilation was equivalent in CIH-exposed and sham animals; however, respiratory timing variability, sigh frequency and ventilation during hypoxic breathing were all lower in CIH-exposed animals. Baseline arterial blood pressure was unaffected by exposure to CIH, but β-adrenoceptor-dependent tachycardia and blunted bradycardia during phenylephrine-induced pressor responses was evident compared with sham controls.
Interpretation:
Increased carotid body chemo-afferent signalling appears obligatory for the development of CIH-induced hypertension and elevated chemoreflex control of breathing commonly reported in mammals, with hypoxia-sensitive carotid bodies. However, we reveal that exposure to modest CIH alters gut microbiota richness and composition, brainstem neurochemistry, and autonomic control of heart rate, independent of carotid body sensitisation, suggesting modulation of breathing and autonomic homeostasis via the microbiota-gut-brainstem axis. The findings have relevance to human sleep-disordered breathing
Comparative Genomics of Cyanobacterial Symbionts Reveals Distinct, Specialized Metabolism in Tropical Dysideidae Sponges.
Marine sponges are recognized as valuable sources of bioactive metabolites and renowned as petri dishes of the sea, providing specialized niches for many symbiotic microorganisms. Sponges of the family Dysideidae are well documented to be chemically talented, often containing high levels of polyhalogenated compounds, terpenoids, peptides, and other classes of bioactive small molecules. This group of tropical sponges hosts a high abundance of an uncultured filamentous cyanobacterium, Hormoscilla spongeliae Here, we report the comparative genomic analyses of two phylogenetically distinct Hormoscilla populations, which reveal shared deficiencies in essential pathways, hinting at possible reasons for their uncultivable status, as well as differing biosynthetic machinery for the production of specialized metabolites. One symbiont population contains clustered genes for expanded polybrominated diphenylether (PBDE) biosynthesis, while the other instead harbors a unique gene cluster for the biosynthesis of the dysinosin nonribosomal peptides. The hybrid sequencing and assembly approach utilized here allows, for the first time, a comprehensive look into the genomes of these elusive sponge symbionts.IMPORTANCE Natural products provide the inspiration for most clinical drugs. With the rise in antibiotic resistance, it is imperative to discover new sources of chemical diversity. Bacteria living in symbiosis with marine invertebrates have emerged as an untapped source of natural chemistry. While symbiotic bacteria are often recalcitrant to growth in the lab, advances in metagenomic sequencing and assembly now make it possible to access their genetic blueprint. A cell enrichment procedure, combined with a hybrid sequencing and assembly approach, enabled detailed genomic analysis of uncultivated cyanobacterial symbiont populations in two chemically rich tropical marine sponges. These population genomes reveal a wealth of secondary metabolism potential as well as possible reasons for historical difficulties in their cultivation
Role of Sterile Neutrino Warm Dark Matter in Rhenium and Tritium Beta Decays
Sterile neutrinos with mass in the range of one to a few keV are important as
extensions of the Standard Model of particle physics and are serious dark
matter (DM) candidates. This DM mass scale (warm DM) is in agreement with both
cosmological and galactic observations. We study the role of a keV sterile
neutrino through its mixing with a light active neutrino in Rhenium 187 and
Tritium beta decays. We pinpoint the energy spectrum of the beta particle, 0 <
T_e < (Q_{beta} - m_s), as the region where a sterile neutrino could be
detected and where its mass m_s could be measured. This energy region is at
least 1 keV away rom the region suitable to measure the mass of the light
active neutrino, located near the endpoint Q_{beta} . The emission of a keV
sterile neutrino in a beta decay could show up as a small kink in the spectrum
of the emitted beta particle. With this in view, we perform a careful
calculation of the Rhenium and Tritium beta spectra and estimate the size of
this perturbation by means of the dimensionless ratio R of the sterile neutrino
to the active neutrino contributions. We comment on the possibility of
searching for sterile neutrino signatures in two experiments which are
currently running at present, MARE and KATRIN, focused on the Rhenium 187 and
Tritium beta decays respectively.Comment: 16 pages, 10 figures. Version to appear in Nucl. Phys. B. Results and
conclusions unchange
Effective Lagrangian Approach to pion photoproduction from the nucleon
We present a pion photoproduction model on the free nucleon based on an
Effective Lagrangian Approach (ELA) which includes the nucleon resonances
(, N(1440), N(1520), N(1535), , N(1650), and
), in addition to Born and vector meson exchange terms. The
model incorporates a new theoretical treatment of spin-3/2 resonances, first
introduced by Pascalutsa, avoiding pathologies present in previous models.
Other main features of the model are chiral symmetry, gauge invariance, and
crossing symmetry. We use the model combined with modern optimization
techniques to assess the parameters of the nucleon resonances on the basis of
world data on electromagnetic multipoles. We present results for
electromagnetic multipoles, differential cross sections, asymmetries, and total
cross sections for all one pion photoproduction processes on free nucleons. We
find overall agreement with data from threshold up to 1 GeV in laboratory
frame.Comment: Misprints corrected. 60 pages. 33 figures.5 tables. Accepted for
publication in Annals of Physics (NY
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Integration of Social, Cultural, and Biomedical Strategies into an Existing Couple-Based Behavioral HIV/STI Prevention Intervention: Voices of Latino Male Couples
Introduction
Successful HIV prevention and treatment requires evidence-based approaches that combine biomedical strategies with behavioral interventions that are socially and culturally appropriate for the population or community being prioritized. Although there has been a push for a combination approach, how best to integrate different strategies into existing behavioral HIV prevention interventions remains unclear. The need to develop effective combination approaches is of particular importance for men who have sex with men (MSM), who face a disproportionately high risk of HIV acquisition.
Materials and Methods
We collaborated with Latino male couples and providers to adapt Connect ‘n Unite, an evidence-based intervention for Black male couples, for Latino male couples. We conducted a series of three focus groups, each with two cohorts of couples, and one focus group with providers. A purposive stratified sample of 20 couples (N = 40, divided into two cohorts) and 10 providers provided insights into how to adapt and integrate social, cultural, and biomedical approaches in a couples-based HIV/AIDS behavioral intervention.
Results
The majority (N = 37) of the couple participants had no prior knowledge of the following new biomedical strategies: non-occupational post-exposure prophylaxis (nPEP); pre-exposure prophylaxis (PrEP); and HIV self-testing kits. After they were introduced to these biomedical interventions, all participants expressed a need for information and empowerment through knowledge and awareness of these interventions. In particular, participants suggested that we provide PrEP and HIV self-testing kits by the middle or end of the intervention. Providers suggested a need to address behavioral, social and structural issues, such as language barriers; and the promotion of client-centered approaches to increase access to, adaptation of, and adherence to biomedical strategies. Corroborating what couple participants suggested, providers agreed that biomedical strategies should be offered after providing information about these tools. Regarding culturally sensitive and responsive approaches, participants identified stigma and discrimination associated with HIV and sexual identity as barriers to care, language barriers and documentation status as further barriers to care, the couple-based approach as ideal to health promotion, and the need to include family topics in the intervention.
Discussion
We successfully adapted an evidence-based behavioral HIV prevention intervention for Latino male couples. The adapted intervention, called Conectando Latinos en Pareja, integrates social, cultural, behavioral and biomedical strategies to address the HIV epidemic among Latino MSM. The study highlights the promise regarding the feasibility of implementing a combination approach to HIV prevention in this populatio
Assessing and augmenting SCADA cyber security: a survey of techniques
SCADA systems monitor and control critical infrastructures of national importance such as power generation and distribution, water supply, transportation networks, and manufacturing facilities. The pervasiveness, miniaturisations and declining costs of internet connectivity have transformed these systems from strictly isolated to highly interconnected networks. The connectivity provides immense benefits such as reliability, scalability and remote connectivity, but at the same time exposes an otherwise isolated and secure system, to global cyber security threats. This inevitable transformation to highly connected systems thus necessitates effective security safeguards to be in place as any compromise or downtime of SCADA systems can have severe economic, safety and security ramifications. One way to ensure vital asset protection is to adopt a viewpoint similar to an attacker to determine weaknesses and loopholes in defences. Such mind sets help to identify and fix potential breaches before their exploitation. This paper surveys tools and techniques to uncover SCADA system vulnerabilities. A comprehensive review of the selected approaches is provided along with their applicability
A Recombinant Potato virus Y Infectious Clone Tagged with the Rosea1 Visual Marker (PVY-Ros1) Facilitates the Analysis of Viral Infectivity and Allows the Production of Large Amounts of Anthocyanins in Plants
"This Document is Protected by copyright and was first published by Frontiers. All rights reserved. It is reproduced with permission."[EN] Potato virus Y (PVY) is a major threat to the cultivation of potato and other solanaceous plants. By inserting a cDNA coding for the Antirrhinum majus Rosea1 transcription factor into a PVY infectious clone, we created a biotechnological tool (PVY-Ros1) that allows infection by this relevant plant virus to be tracked by the naked eye with no need for complex instrumentation. Rosea1 is an MYB-type transcription factor whose expression activates the biosynthesis of anthocyanin pigments in a dose-specific and cell-autonomous manner. Our experiments showed that the mechanical inoculation of solanaceous plants with PVY-Ros1 induced the formation of red infection foci in inoculated tissue and solid dark red pigmentation in systemically infected tissue, which allows disease progression to be easily monitored. By using silver nanoparticles, a nanomaterial with exciting antimicrobial properties, we proved the benefits of PVY-Ros1 to analyze novel antiviral treatments in plants. PVY-Ros1 was also helpful for visually monitoring the virus transmission process by an aphid vector. Most importantly, the anthocyanin analysis of infected tobacco tissues demonstrated that PVY-Ros1 is an excellent biotechnological tool for molecular farming because it induces the accumulation of larger amounts of anthocyanins, antioxidant compounds of nutritional, pharmaceutical and industrial interest, than those that naturally accumulate in some fruits and vegetables well known for their high anthocyanin content. Hence these results support the notion that the virus-mediated expression of regulatory factors and enzymes in plants facilitates easy quick plant metabolism engineering.This research was supported by grants BIO2014-54269-R and AGL2013-49919-EXP to J-AD and AGL2013-42537-R to J-JL-M from the Ministerio de Economia y Competitividad (MINECO, co-financed FEDER funds), Spain. MM was supported by the Erasmus Mundus Scholarship-ACTION 2 WELCOME program of the European Commission. Research in CRAG is supported in part by CERCA (Generalitat de Catalunya) and by "Severo Ochoa Programme for Centres of Excellence in R&D" 2016-2019 (SEV-2015-0533).Cordero, T.; Mohamed, M.; Lopez Moya, J.; Daros Arnau, JA. (2017). A Recombinant Potato virus Y Infectious Clone Tagged with the Rosea1 Visual Marker (PVY-Ros1) Facilitates the Analysis of Viral Infectivity and Allows the Production of Large Amounts of Anthocyanins in Plants. 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