1,455 research outputs found
GINZBURG-LANDAU THEORY OF VORTICES IN -WAVE SUPERCONDUCTORS
Ginzburg-Landau theory is used to study the properties of single vortices and
of the Abrikosov vortex lattice in a superconductor. For a single
vortex, the -wave order parameter has the expected four-lobe structure in a
ring around the core and falls off like at large distances. The
topological structure of the -wave order parameter consists of one
counter-rotating unit vortex, centered at the core, surrounded by four
symmetrically placed positive unit vortices. The Abrikosov lattice is shown to
have a triangular structure close to and an oblique structure at lower
temperatures. Comparison is made to recent neutron scattering data.Comment: 4 pages, REVTeX, 3 figures available upon reques
Association of the CCR5 gene with juvenile idiopathic arthritis
The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction. A 32 base-pair insertion/deletion variant (CCR5Δ32) within the gene leads to a frame shift and a nonfunctional receptor. CCR5Δ32 has been investigated for its association with juvenile idiopathic arthritis (JIA), with conflicting results. The aim of this study was to investigate whether CCR5Δ32 is associated with JIA in an UK population. CCR5Δ32 was genotyped in JIA cases (n=1054) and healthy controls (n=3129) and genotype and allele frequencies were compared. A meta-analysis of our study combined with previously published studies was performed. CCR5Δ32 was significantly associated with protection from developing JIA, in this UK data set (P(trend)=0.006, odds ratio (OR) 0.79 95% confidence interval (95% CI): 0.66-0.94). The meta-analysis of all published case-control association studies confirmed the protective association with JIA (P=0.001 OR 0.82 95% CI: 0.73-0.93). CCR5Δ32 is a functional variant determining the number of receptors on the surface of T cells, and it is hypothesized that the level of CCR5 expression could influence the migration of proinflammatory T cells into the synovium and thus susceptibility to JIA
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic arthritis (JIA) susceptibility loci, specifically, PTPN22 and IL2RA. Several novel autoimmune susceptibility loci have recently been identified, and we hypothesise that single-nucleotide polymorphisms (SNPs) within these genes may also be JIA susceptibility loci. Five SNPs within the genes AFF3, IL2/IL21, IL7R, CTLA4 and CD226, previously associated with multiple autoimmune diseases were genotyped, in a large data set of Caucasian JIA patients and controls, and tested for association with JIA. We identified two susceptibility loci for JIA, AFF3 and the IL2/IL21 region and additional weak evidence supporting an association with the CTLA4 and IL7R genes, which warrant further investigation. All results require validation in independent JIA data sets. Further characterisation of the specific causal variants will be required before functional studies can be performed
Management of Trickle Irrigated Orchards for Increased Water Use Efficiency
Trickle irrigation is the most efficient method of irrigating peach orchards in Texas. With a trickle irrigation system, a producer may make full use of a limited or low-volume water supply to apply precise amounts of water to the root zones of individual trees. Improved irrigation scheduling methods offer the potential for further savings in water and energy to pressurize the water since peach trees require less than a fully-watered state for production. This report describes research to determine the crop coefficients for peach trees that would result in an optimum irrigation schedule. One major effort evaluated the physiological response of the peach tree to varying irrigation regimes. This thrust indicated that a crop coefficient as low as 0.53 produced similar physiological responses (leaf water potential, leaf resistance, and transpiration rate) as a crop coefficient of 0.7. The critical period for initiation of stress was during the period before harvest. A large twin weighing lysimeter facility was designed and installed. Preliminary results for mature peach trees showed water use rates at the maximum evapotranspiration rate approached a crop coefficient of 1.0. The research indicates that the peach tree is a luxury consumer of water; improved irrigation scheduling is achievable
Does maximising ball speed in cricket fast bowling necessitate higher ground reaction forces?
This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Sports Sciences on 17th July 2015, available online: http://www.tandfonline.com/10.1080/02640414.2015.1069375.This study aimed to investigate whether high peak ground reaction forces and high average loading rates are necessary to bowl fast. Kinematic and kinetic bowling data were collected for 20 elite male fast bowlers. A moderate non-significant correlation was found between ball speed and peak vertical ground reaction force with faster bowlers tending to have lower peak vertical ground reaction force (r = −0.364, P = 0.114). Faster ball speeds were correlated with both lower average vertical and lower average horizontal loading rates (r = −0.452, P = 0.046 and r = −0.484, P = 0.031, respectively). A larger horizontal (braking) impulse was associated with a faster ball speed (r = 0.574, P = 0.008) and a larger plant angle of the front leg (measured from the vertical) at front foot contact was associated with a larger horizontal impulse (r = 0.706, P = 0.001). These findings suggest that there does not necessarily need to be a trade-off between maximum ball release speed and the forces exerted on fast bowlers (peak ground reaction forces and average loading rates). Furthermore, it appears that one of the key determinants of ball speed is the horizontal impulse generated at the ground over the period from front foot contact until ball release
Conservation genetics of the pond bat (Myotis dasycneme) with special focus on the populations in northwestern Germany and in Jutland, Denmark
Conservation genetics is important in the management of endangered species, helping to understand their connectivity and long‐term viability, thus identifying populations of importance for conservation. The pond bat (Myotis dasycneme) is a rare species classified as “Near Threatened” with a wide but patchy Palearctic distribution. A total of 277 samples representing populations in Denmark, Germany, Latvia, Hungary, and Russia were used in the genetic analyses; 224 samples representing Denmark, Germany, and Russia were analyzed at 10 microsatellite loci; 241 samples representing all areas were analyzed using mitochondrial D‐loop and cytochrome B sequences. A Bayesian clustering approach revealed two poorly resolved clusters, one representing the Danish and German groups and the other the Russian group. However, significantly different pairwise FST and DEST estimates were observed between the Danish and German groups and between the Danish and Russian groups suggesting a recent population structure. These conflicting results might be attributed to the effect of migration or low resolution due to the number of microsatellite markers used. After concatenating the two mitochondrial sequences, analysis detected significant genetic differentiation between all populations, probably due to genetic drift combined with a founder event. The phylogenetic tree suggested a closer relationship between the Russian and Northern European populations compared to the Hungarian population, implying that the latter belongs to an older ancestral population. This was supported by the observed haplotype network and higher nucleotide diversity in this population. The genetic structuring observed in the Danish/German pond bat stresses the need for a cross‐border management between the two countries. Further, the pronounced mtDNA structuring, together with the indicated migration between nearby populations suggest philopatric female behavior but male migration, emphasizes the importance of protecting suitable habitat mosaics to maintain a continuum of patches with dense pond bat populations across the species' distribution range
- …