16 research outputs found
Meeting Places of Life, Poetry and Theatre: 'The Circus Animals' Desertion'
'The Circus Animals' Desertion' is a poem about the intertwining of life and art: the ageing poet, in his seventies, looks back at work written in his twenties and in early middle age, scrutinising it to see how much of his real life went into it. The poem was published (in journals) in January 1939, the month in which Yeats died, so has the poignancy of last words. But it offers another special fascination; the impression it gives us of being taken behind the scenes, shown the play from the ..
Studies on W.B. Yeats
Dans ce recueil convergent différents regards sur la poésie de W.B. Yeats. Ces pages le situent par rapport à d’autres poètes comme MacNeice. Elles nous promènent aussi des premiers volumes, où l’espace de l’écriture devient l’écriture de l’espace, à Responsabilities, volume qui témoigne d’une intensité qu’Ezra Pound qualifie de « robustesse nouvelle », puis à travers les thèmes sexuels, politiques et esthétiques de Michael Robartes and the Dancer. Nous abordons ensuite les grands poèmes de la maturité avec The Tower. Cet ouvrage envisage également des sujets généraux, comme l’importance de la tradition pour Yeats, sa conception de l’au-delà avec la dette envers l’Inde en particulier, son attitude face à la dégénérescence, sa vision de l’Apocalypse avec le symbole de la spirale. D’autres études se concentrent sur certains grands poèmes tels que « The Circus Animais Desertion », qui tisse ensemble et la vie et l’art, ou « Lapis Lazuli » et la notion de « joie tragique ».In this book, different perspectives on W. B. Yeats' poetry converge. These pages place him in relation to other poets such as MacNeice. They also take us from the first volumes, where the space of writing becomes the writing of space, to Responsabilities, a volume that reflects an intensity that Ezra Pound calls "new robustness", and then through the sexual, political and aesthetic themes of Michael Robartes and the Dancer. We then discuss the great poems of maturity with The Tower. This book also considers general topics, such as the importance of tradition for Yeats, his conception of the afterlife with the debt to India in particular, his attitude towards degeneration, his vision of the Apocalypse with the symbol of the spiral. Other studies focus on some major poems such as "The Circus Animais Desertion", which weaves together life and art, or "Lapis Lazuli" and the notion of "tragic joy"
Brincidofovir is highly efficacious in controlling adenoviremia in pediatric recipients of hematopoietic cell transplant
Cidofovir is preemptively used for controlling adenoviremia and preventing disseminated viral disease in hematopoietic cell transplant (HCT) recipients but does not lead to resolution of viremia without T-cell immune-reconstitution. The lipid-conjugated prodrug of cidofovir, brincidofovir, has improved oral bioavailability and achieves higher intracellular concentrations of active drug. We present retrospective multicenter data comparing the kinetics of viremia and toxicities following preemptive treatment with and brincidofovir in children and adolescents diagnosed with HCT-related adenoviremia. Forty-one episodes (18 = brincidofovir; 23 = cidofovir) of antiviral therapy were observed in 27 patients. The 2 groups had comparable immune-reconstitution and viral burden. Major (≥2 log-reduction in 2 weeks; n = 13) and minor (≥1 to ≤2 log-reduction in 2 weeks; n = 2) virological responses were observed in 15 (83%) brincidofovir episodes compared to only 2 (9%) major virological responses with cidofovir (P < .0001). Brincidofovir mediated major responses in 9 of 11 cidofovir-unresponsive patients and resulted in complete responses (CR) despite significant lymphopenia (Brincidofovir vs cidofovir; CR = 13 (80%) vs 8 (35%); median lymphocyte count = 320/μl vs 910/μl; P < .05). One patient experienced abdominal cramps and diarrhea necessitating interruption of brincidofovir and none developed nephrotoxicity with brincidofovir. Thus, brincidofovir is well-tolerated and highly efficacious in controlling adenoviremia during the lymphopenic phase of HCT