Trust and Formal Control in interorganizational Relationships

There is a tendency to see trust and control by formal agreements as substitutes. According to transaction cost economics trust is unreliable, and some form of control is needed to reduce hazards of opportunism. According to others, high trust allows for a limited extent of formal control. Formal control signals distrust and thereby evokes reciprocal distrust and formal control. This paper studies all combinations of high/low trust and high/low formal control in four longitudinal case studies. We find that trust and formal control are at least as much complements as they are substitutes. We find that like trust contracts can be both the basis and the outcome of relations.governance;inter-organizational relations;trust;contract

The National Systems of Innovation Approach and Innovation by SMEs

The National Systems of Innovation (NSI) approach is a young but successful approach to help to understand how innovation and interactive learning evolve in national economies and how they propel economic prosperity and international competitiveness. The NSI approach has been embraced by policy makers all around the world, because this approach offers them the potential to derive more appropriate leads for innovation policy. In the Netherlands too, the drafting of innovation policy is increasingly based on the NSI concept. The main aim of this study is to add to the understanding of the NSI approach. The research questions addressed in this study include: What are the main concepts, value added and shortcom-ings of the approach? And: How does the NSI approach offer policy makers the potential to derive more appropriate leads for innovation policy towards SMEs?

The effects of trust on performance of high-tech business relationships

We investigate the effects of trust propensity, cognition based trust and affect based trust on relationship performance in terms of openness, conflicts and success. Data from a field study of 391 Dutch firms in high tech industries support the research model. Trust that derives from affection is key and outweighs cognition based trust and trust propensity. Openness increases success that in turn fosters the development of affect based trust. The results provide preliminary but convincing evidence for the value of relational capital in durable business relationships that strive for the development of new technological knowledge.

Contractual Alliance Governance: Impact of Different Contract Functions on Alliance Performance

Recent research on alliance governance has emphasized that contracts can have both a control and coordination function. In this paper, we test the impact of these different contract functions on alliance performance. Conducting structural equation analyses on a sample of 270 Dutch technology alliances, we disentangle the relationship between different contract functions, partner cooperation and alliance success. Our data show that different contract roles have a different impact on partner cooperation within the alliance. In addition, we find strong indications that the presence/absence of prior trustful collaboration and the number of alliance partners moderate the relationship between contract functions and partner cooperation. Finally, our data provide evidence that contract functions indirectly influence alliance success via partner cooperation

Learning towards system innovation.Evaluating a systemic instrument.

In this paper we develop an analytical framework for studying learning processes in the context of efforts to bring about system innovation by building new networks of actors who are willing to work on a change towards sustainable development. We then use it to evaluate two specific intervention programmes carried out by a self-proclaimed ‘system instrument’. The framework integrates elements from the Innovation Systems approach with a social learning perspective. The integrated model proposes essentially that these kinds of systemic instruments can serve to enhance conditions for social learning and that such processes may result in learning effects that contribute to system innovation by combatting system imperfections. The empirical findings confirm the assumption that differences in learning can be explained by the existence or absence of conditions for learning. Similarly, the existence or creation of conducive conditions could be linked to the nature and quality of the interventions of the systemic instrument. We conclude that the investigated part of the hypothesised model has not been refuted and seems to have explanatory power. At the same time we propose that further research is needed among others on the relation between learning, challenging system imperfections and system innovation.social learning, system innovation, systemic instruments, system imperfections, innovation systems

Trust and Formal Control in interorganizational Relationships

There is a tendency to see trust and control by formal agreements as substitutes. According to transaction cost economics trust is unreliable, and some form of control is needed to reduce hazards of opportunism. According to others, high trust allows for a limited extent of formal control. Formal control signals distrust and thereby evokes reciprocal distrust and formal control. This paper studies all combinations of high/low trust and high/low formal control in four longitudinal case studies. We find that trust and formal control are at least as much complements as they are substitutes. We find that like trust contracts can be both the basis and the outcome of relations

Paradoxical down-regulation of p16INK4a mRNA with advancing age in Acute Myeloid Leukemia

Aging is generally considered to be the consequence of stem cell attrition caused by the activity of tumor suppressor pathways that censor potentially malignant clones by eliciting apoptosis or senescence. An important effector of aging is the cyclindependent kinase inhibitor p16INK4a, which is also a known suppressor of cancer. The expression of p16INK4a is very low or absent in young organisms but increases with advancing age. We recently showed that, unlike healthy cells, acute myeloid leukemia (AML) derived blasts show a down-regulation of p16INK4a mRNA with increasing age. Based on this observation we hypothesize that suppression of defense mechanisms which protect older cells against cellular and DNA damage might facilitate oncogenesis in older individuals