7,080 research outputs found

    The timing of disability insurance application: a choice-based semiparametric hazard model

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    We use a choice-based subsample of Social Security Disability Insurance applicants from the 1978 Social Security Survey of Disability and Work to test the importance of policy variables on the timing of application for disability insurance benefits following the onset of a work limiting health condition. We correct for choice-based sampling by extending the Manski-Lerman (1977) correction to the likelihood function of our continuous time hazard model defined with semiparametric unmeasured heterogeneity and find that this correction significantly affects the results. We find that economic variables-the size of the disability benefit, expected wage earnings and accommodation-matter.Insurance ; Social security

    Isobar of an ideal Bose gas within the grand canonical ensemble

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    We investigate the isobar of an ideal Bose gas confined in a cubic box within the grand canonical ensemble, for a large yet finite number of particles, N. After solving the equation of the spinodal curve, we derive precise formulae for the supercooling and the superheating temperatures which reveal an N^{-1/3} or N^{-1/4} power correction to the known Bose-Einstein condensation temperature in the thermodynamic limit. Numerical computations confirm the accuracy of our analytical approximation, and further show that the isobar zigzags on the temperature-volume plane if N is greater than or equal to 14393. In particular, for the Avogadro's number of particles, the volume expands discretely about 10^5 times. Our results quantitatively agree with a previous study on the canonical ensemble within 0.1% error.Comment: 6 pages, 2 figures; Reference added. Accepted for publication in Phys. Rev.

    Isolation, phenotype, and allostimulatory activity of mouse liver dendritic cells

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    Donor liver-derived dendritic cells (DC) have recently been identified within various lymphoid and nonlymphoid tissues of organ allograft recipients, including nonimmunosuppressed mice transplanted with and permanently accepting major histocompatibility complex (MHC)-disparate hepatic allografts. These findings have raised questions about the basis of the tolerogenicity of the liver—and, in particular, about the properties of liver-derived DC. To study further the structure, immunophenotype and allostimu-latory activity of leukocytes resident in normal mouse (B10.BR; H-2k, I-Ek) liver, a procedure was developed to maximize the yield of viable, nonparenchymal cells (NPC) obtained following collagenase digestion of perfused liver fragments and density centrifugation (Per-coll). These cells comprised populations expressing lymphoid and myeloid cell surface antigens. As compared with spleen cells, they proved good allostimula-tors of naive (BIO; H-2b, I-E") splenic T cells when tested in primary mixed leukocyte reactions (MLR). After overnight (18-hr) incubation of the NPC, enrichment for transiently adherent, low-density (LD) cells on metrizamide gradients permitted the recovery of low numbers of cells (approx. 2-5 × 105 per liver), many of which displayed distinct DC morphology. Flow cytometric analysis revealed that these cells were CD3-, CD4-, CD8-, and B220-, but strongly expressed CD45 (leukocyte-common antigen), and mild-to-moderate levels of CD lib, heat-stable antigen, and CD44. The cells also expressed moderate intensity of NLDC 145 but not 33D1, DC restricted markers which have been shown to be differentially expressed on mouse DC isolated from various organs. This DC-enriched population was more strongly MHC class II(I-Ek)+ than NPC, as determined by immunocytochemistry and flow cytometry and exhibited much more potent allo-stimulatory activity for naive T cells. These findings demonstrate that freshly isolated murine liver NPC, and perhaps their counterparts in situ, exhibit allo-stimulatory activity that is enhanced in the nonadherent, low-density (DC-enriched) fraction after overnight culture. They further suggest that the © 1994 by Williams and Wilkins

    A Novel On-chip Three-dimensional Micromachined Calorimeter with Fully Enclosed and Suspended Thin-film Chamber for Thermal Characterization of Liquid Samples

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    A microfabricated calorimeter (μ-calorimeter) with an enclosed reaction chamber is presented. The 3D micromachined reaction chamber is capable of analyzing liquid samples with volume of 200 nl. The thin film low-stress silicon nitride membrane is used to reduce thermal mass of the calorimeter and increase the sensitivity of system. The μ-calorimeter has been designed to perform DC and AC calorimetry, thermal wave analysis, and differential scanning calorimetry. The μ-calorimeter fabricated with an integrated heater and a temperature sensor on opposite sides of the reaction chamber allows to perform thermal diffusivity and specific heat measurements on liquid samples with same device. Measurement results for diffusivity and heat capacitance using time delay method and thermal wave analysis are presented

    Thermal fluctuation field for current-induced domain wall motion

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    Current-induced domain wall motion in magnetic nanowires is affected by thermal fluctuation. In order to account for this effect, the Landau-Lifshitz-Gilbert equation includes a thermal fluctuation field and literature often utilizes the fluctuation-dissipation theorem to characterize statistical properties of the thermal fluctuation field. However, the theorem is not applicable to the system under finite current since it is not in equilibrium. To examine the effect of finite current on the thermal fluctuation, we adopt the influence functional formalism developed by Feynman and Vernon, which is known to be a useful tool to analyze effects of dissipation and thermal fluctuation. For this purpose, we construct a quantum mechanical effective Hamiltonian describing current-induced domain wall motion by generalizing the Caldeira-Leggett description of quantum dissipation. We find that even for the current-induced domain wall motion, the statistical properties of the thermal noise is still described by the fluctuation-dissipation theorem if the current density is sufficiently lower than the intrinsic critical current density and thus the domain wall tilting angle is sufficiently lower than pi/4. The relation between our result and a recent result, which also addresses the thermal fluctuation, is discussed. We also find interesting physical meanings of the Gilbert damping alpha and the nonadiabaticy parameter beta; while alpha characterizes the coupling strength between the magnetization dynamics (the domain wall motion in this paper) and the thermal reservoir (or environment), beta characterizes the coupling strength between the spin current and the thermal reservoir.Comment: 16 page, no figur

    Excitation spectroscopy of vortex lattices in a rotating Bose-Einstein condensate

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    Excitation spectroscopy of vortex lattices in rotating Bose-Einstein condensates is described. We numerically obtain the Bogoliubov-deGenne quasiparticle excitations for a broad range of energies and analyze them in the context of the complex dynamics of the system. Our work is carried out in a regime in which standard hydrodynamic assumptions do not hold, and includes features not readily contained within existing treatments.Comment: 4 pages, 4 figures. Submitted for publicatio
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