A Mobile App to Aid Smoking Cessation: Preliminary Evaluation of SmokeFree28

Background: Little is known about the effectiveness of mobile apps in aiding smoking cessation or their validity for automated collection of data on smoking cessation outcomes. Objective: We conducted a preliminary evaluation of SF28 (SF28 is the name of the app, short for SmokeFree28)—an app aimed at helping smokers to be smoke-free for 28 days. / Methods: Data on sociodemographic characteristics, smoking history, number of logins, and abstinence at each login were uploaded to a server from SF28 between August 2012 and August 2013. Users were included if they were aged 16 years or over, smoked cigarettes at the time of registration, had set a quit date, and used the app at least once on or after their quit date. Their characteristics were compared with data from a representative sample of smokers trying to stop smoking in England. The percentage of users recording 28 days of abstinence was compared with a value of 15% estimated for unaided quitting. Correlations were assessed between recorded abstinence for 28 days and well-established abstinence predictors. / Results: A total of 1170 users met the inclusion criteria. Compared with smokers trying to quit in England, they had higher consumption, and were younger, more likely to be female, and had a non-manual rather than manual occupation. In total, 18.9% (95% CI 16.7-21.1) were recorded as being abstinent from smoking for 28 days or longer. The mean number of logins was 8.5 (SD 9.0). The proportion recording abstinence for 28 days or longer was higher in users who were older, in a non-manual occupation, and in those using a smoking cessation medication. / Conclusions: The recorded 28-day abstinence rates from the mobile app, SF28, suggest that it may help some smokers to stop smoking. Further evaluation by means of a randomized trial appears to be warranted

ICT implementation and school leadership: Case studies of ICT integration in teaching and learning

The Hong Kong Special Administrative Region (SAR) government launched a five-year ICT strategy in schools in late 1998. This paper reports the findings of the analysis on models of change in 18 schools striving to integrate the use of ICT in teaching and learning across the school curriculum. The study shows that the strategy adopted by a school in instituting such change and the resulting variation of pedagogical practices using ICT is strongly dependent on the school leaders’ vision and understanding of the role and impact of ICT in the curriculum, their goals and objectives for ICT integration, as well as the history, culture and background of the school and its general vision and mission.published_or_final_versio

Protection offered by root-surface restorative materials against biofilm challenge

The prevalence of root-surface caries is increasing. We hypothesized that some restorative materials are protective against cariogenic challenge on root surfaces. Our goal was to study the effects of different restorative materials on root surfaces incubated with an oral biofilm generated in an artificial mouth. A biofilm of Streptococcus mutans, Streptococcus sobrinus, Lactobacillus rhamnosus, and Actinomyces naeslundii was co-cultured for 21 days on 24 glass-ionomer cement, resin-modified glassionomer cement, or resin-composite-restored root surfaces. These surfaces were then examined with Fourier transform infrared spectroscopy and scanning electron energy-dispersive spectroscopy. Only glass-ionomer restorations showed a significant increase in log calcium-to-phosphorus ratio (P < 0.01), and a significantly lower log amide I-to-hydrogen phosphate ratio on the root surface after incubation in the artificial mouth. Glass-ionomer restoratives conferred a preventive effect on the root surfaces against initial cariogenic challenge with a mixed-species oral biofilm without therapeutic intervention.published_or_final_versio

Assessment of the health impacts and economic burden arising from proposed new air quality objectives in a high pollution environment

We conducted a health impact assessment of the government’s proposed new air quality objectives (AQO) in Hong Kong, a high pollution environment. We based this on the World Health Organization (WHO) 2005 Air Quality Guidelines (AQG) and used a lognormal probability density function to model possible changes in annual mean pollutant levels resulting from the new AQO. All of the proposed short-term AQO were based on WHO interim targets (IT) or AQG, but allowed additional exceedances of these single limit values. Compliance with these short-term AQO may reduce (18-30%) the current annual mean concentrations but the distribution proportions exceeding the annual or annualized AQG remain high (83-100%). For SO2, the proposed 24-hr AQO of 125 µg m-3, with 3 days exceedances, cannot ensure reduction of the current annual mean but may legally permit an increase of the pollutant concentration distribution. If the proposed legal limits of AQO are fully exploited by polluters, we estimated the annual number of avoidable deaths at 1860, and avoidable health care events at 5.2 million doctor visits and 92745 hospital bed-days with a total annual community cost of US$2.6 billion. The proposed AQO may only reduce the current air pollution health impacts by 17% but could achieve 41% reduction if additional exceedances were not permitted. An epidemiologic approach should be adopted to assess external costs arising from modifications of WHOAQG and support accountability in air quality management. This analysis of the WHOAQG in a high pollution setting demonstrates problems arising from the absence of annual limits for some pollutants and the discordance between the short-term and annual AQG, suggesting that revisions based on a lognormal probability model should be considered.published_or_final_versio

An Unanswered Question about Heavy Metals in Chinese Herbal Medicinal Preparations: Environmental Contamination or Medicinal Elements?

Plenary Session 1: Translational/Population Studiespublished_or_final_versio

Utilization of glucose, blood pressure, and lipid lowering medications among people with type II diabetes in the United States, 1999-2010

postprin

Editorial: Advanced methods for public transport system management

published_or_final_versionSpringer Open Choice, 01 Dec 201

Effect of crystallinity on electrostatic charging in DPI formulations

Poster Presentation: no. 13PS41Introduction: Many physicochemical, mechanical and environmental factors can influence charging of dry powder inhaler (DPI) formulations - crystallinity is one of these factors. Due to differences in crystal packing and surface energies, there may be differences in charge transfer behaviours between amorphous and crystalline materials. Although the effect of crystallinity on electrostatic charging in DPI formulations has been investigated previously by other researchers, the reported data were inconclusive since the samples not only differed in crystallinity, but also in particle morphology and size distributions. Therefore, these variables are controlled in the present study to determine the role of crystallinity in electrostatic charging of DPI formulations. The objective of this study was to characterize inherent charges generated by amorphous and crystalline micron-sized salbutamol sulfate (SS) powders .....published_or_final_versio

Impact of COVID-19 pandemic on serum vitamin D level among infants and toddlers: An interrupted time series analysis and before-and-after comparison

Background: During the coronavirus disease 2019 (COVID-19) pandemic, the implementation of social distancing and home confinement measures may elevate the risk of vitamin D deficiency particularly for infants. This study aimed to quantify changes in vitamin D level among infants and toddlers in Hong Kong after the COVID-19 outbreak. Methods: We recruited 303 infants and toddlers aged 2–24 months by stratified random sampling from 1 June 2019 to November 30, 2020. Regression models were used to estimate the effect of time on infants’ serum 25-hydroxyvitamin D (25(OH)D) level overall and by age groups before and after the outbreak. Interrupted time series (ITS) analysis was performed to examine the sustained effect of COVID-19 on their serum 25(OH)D level. Results: The ITS results showed no immediate reduction in serum 25(OH)D level among infants, but a decreasing trend was observed in the subsequent months post-outbreak at a monthly decline rate of −6.32 nmol/L. When analyzed by age group, the magnitude of post-outbreak reduction in 25(OH)D was stronger among younger infants (aged 2–6 months). Conclusion: Guidelines and recommendations should be given to pregnant women and mothers to ensure sufficient vitamin D level in their infants during the COVID-19 period

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