Discovery of a faint optical jet in 3C 120

We report the detection of an optical jet in the nearby Seyfert 1 radio galaxy 3C 120. The optical jet coincides with the well-known radio jet and emits continuum radiation (B,V',I) with a radio-to-optical spectral index of 0.65. There are no clear optical counterparts to the radio knots, although the optical condensation A of the galaxy, which includes the bright 4" radio knot, is found to be 12 % polarized with the electric field vectors perpendicular to the jet. These findings indicate that 3C 120 contains the 6th known extragalactic optical synchrotron jet, quite similar in its properties to the jet of PKS 0521-36. The outer parts of the jet is the faintest known optical jet and was discovered as the result of a dedicated effort to detect it. It is therefore possible that more optical jets can be discovered in systematic searches by combining deep imaging in the optical or near-IR with careful galaxy subtraction methods

The Structure and Motions of the 3C~120 Radio Jet on Scales of 0.6 to 300 Parsecs

Results are presented from long term VLBI monitoring of the parsec-scale radio jet in 3C120, primarily at 5 and 1.7 GHz. Numerous superluminal features are followed, some over large fractional distances from the core. The speeds of the features are not all the same, but vary by less than a factor of 2. The superluminal features extend to core distances of over 0.2 arcseconds and the region of slowing has not been found. The 1.7 GHz images show evidence for stationary features in addition to the superluminal features. The structure of the jet in the vicinity of the most likely stationary feature is suggestive of a helical pattern seen in projection. The deprojected wavelength of the pattern is very long relative to the jet radius, unlike the situation in sources such as M87. If the 3C120 jet does contain a slowly-moving, helical structure, then theory suggests that the jet resides in a relatively cool medium, not in a relativistically hot cocoon or lobe.Comment: 35 pages with 8 postscript figures. Accepted for publication in the Astrophysical Journa

OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis

SummaryBackgroundJoint space width (JSW) evaluated in millimeters on plain X-rays is the currently optimal recognized technique to evaluate osteoarthritis (OA) structural progression. Data obtained can be presented at the group level (e.g., mean±standard deviation of the changes). Such presentation makes difficult the interpretation of the clinical relevance of the reported results. Therefore, a presentation at the individual level (e.g., % progressors) seems more attractive but requires to determining a cut-off. Several methodologies have been proposed to define cut-offs in JSW: arbitrary chosen cut-off, cut-off based on the validity to predict a relevant end-point such as the requirement of total articular replacement or cut-off based on the measurement error such as smallest detectable difference (SDD).ObjectivesThe objective of this OARSI–OMERACT initiative was to define a cut-off evaluated in millimeters on plain X-rays above which a change in JSW could be considered as relevant in patients with hip and knee OA.MethodsThe first step consisted in a systematic literature research performed using Medline database up to July 2007 to obtain all manuscripts published between 1990 and 2007 reporting a cut-off value in JSW evaluated in millimeters at either the knee or hip level. The second step consisted in a consensus based on the best knowledge of the 11 experts with the support of the available evidence.ResultsAmong the 506 articles selected by the search, 47 articles reported cut-off of JSW in millimeters. There was a broad heterogeneity in cut-off values, whatever the methodologies or the OA localization considered (e.g., from 0.12 to 0.84mm and from 0.22 to 0.78mm for Knee (seven studies) and hip (seven studies), respectively when considering the data obtained based on the reliability). Based on the data extracted in the literature, the expert committee proposed a definition of relevant change in JSW based on plain X-rays, on an absolute change of JSW in millimeters and on the measurement error e.g., calculation of the SDD using the Bland and Altman technique. The results of the analysis of JSW should be expressed in terms of a dichotomous variable (e.g., progressors yes/no): a patient with a change in JSW during the study over such SDD will fulfill the definition of “progressor”. Moreover, the pilot study aimed at evaluating the measurement error should be designed to reflect the different characteristics of the primary study in which the analysis of the radiological findings will be based on (patient's characteristics, centers characteristics, readers).ConclusionThis initiative based on both an Evidence Based Medicine (Systematic Literature Research) and Expert Opinion approach resulted in a proposal of definition of relevant radiological progression in OA to be used as end-point in clinical trials and also recommendations on the conduct of the reliability study allowing such definition