Relative performance of four midge-resistant wheat varietal blends in western Canada

Non-Peer ReviewedOrange wheat blossom midge, Sitodiplosis mosellana (Géhin), causes significant yield losses to spring wheat in western Canada in severe infestations. To mitigate losses, midge-resistant wheat varietal blends, consisting of cultivars carrying the Sm1 midge resistance gene and 10% interspersed midge susceptible refuge, have been made available to farmers. To test their performance relative to conventional midge-susceptible cultivars, four varietal blends were grown during four consecutive years, at eight locations in the provinces of Manitoba Saskatchewan and Alberta, in comparison to four conventional, midge-susceptible cultivars. Midge damage was higher in 2007 and 2010 than in 2008 and 2009. In general, the varietal blends, as a group, yielded more grain than the susceptible cultivars, especially when grown in environments with high midge pressure (5.5 - 35% seed damage). In environments with low midge pressure (0 – 2.6% seed damage), the varietal blend average yield advantage was smaller but still significant, indicating that some of the varietal blends had additional superior attributes, in addition to midge resistance

The effect of incorporating the midge resistance (Sm1) gene in wheat

Non-Peer ReviewedOrange wheat blossom midge, Sitodiplosis mosellana (Géhin), was first detected in Manitoba in 1901, but now is present in all three prairie provinces of western Canada. In severe infestations, this insect may cause significant yield losses to spring wheat. To mitigate losses, midge-resistant wheat varietal blends, consisting of cultivars carrying the Sm1 midge resistance gene and 10% interspersed midge susceptible refuge, are now available to farmers. The refuge prevents this resistance to be overcome by the insect. To test the field performance of these varietal blends, relative to conventional midge-susceptible cultivars, four varietal blends were grown during four consecutive years, at eight locations in the provinces of Manitoba Saskatchewan and Alberta, in comparison to four conventional, midge-susceptible cultivars. Midge damage was higher in 2007 and 2010, than in 2008 and 2009. In general, the varietal blends, as a group, yielded more grain than the susceptible cultivars, especially when grown in environments with high midge pressure (5.5 - 35% seed damage). In environments with low midge pressure (0 – 2.6% seed damage), the varietal blend average yield advantage was smaller but still significant, indicating that some of the varietal blends had additional superior attributes, in addition to midge resistance. Significant differences in midge damage were observed within the resistant and the susceptible groups of the cultivars tested. Midge resistance did not protect wheat against loss of market grade

Cerebrovascular Variants and the Role of the Selfish Brain in Young-Onset Hypertension

Background: Variants in the posterior anatomy of the cerebral circulation are associated with hypertension and lower cerebral blood flow in midlife (age ≈55 years); however, whether these variants are a result of aging or long-term exposure to high blood pressure is unclear. Additionally, the role these variants play in early onset of hypertension (<40 years) and poor cerebral perfusion in this population is unknown. Methods: We retrospectively examined whether specific cerebrovascular variants (vertebral artery hypoplasia and absent/hypoplastic posterior communicating arteries (an incomplete posterior circle of Willis) measured via magnetic resonance angiography) were associated with a diagnosis of hypertension in 220 young adults (<40 years; n=164 primary hypertensive [mean age±SD, 32±6 years] and n=56 [30±6 years] normotensive adults). Whether cerebrovascular variants were associated with lower cerebral blood flow (phase-contrast angiography) was measured in the hypertensive group only (n=146). Results: Binary logistic regression (adjusted for age, sex, and body mass index) showed that vertebral artery hypoplasia with an incomplete posterior circle of Willis was associated with hypertension diagnosis (P<0.001, odds ratio; 11.79 [95% CI, 3.34–41.58]). Vertebral artery hypoplasia plus an incomplete circle of Willis was associated with lower cerebral blood flow in young adults with hypertension (P=0.0172). Conclusions: Vertebral artery hypoplasia plus an incomplete posterior circle of Willis independently predicts hypertension in young adults suggesting that this variant is not acquired with aging into midlife. Importantly this variant combination was associated with lower cerebral perfusion, which may have long-term consequences on cerebrovascular health in young adults with hypertension

Enhanced Nonperturbative Effects in Z Decays to Hadrons

We use soft collinear effective field theory (SCET) to study nonperturbative strong interaction effects in Z decays to hadronic final states that are enhanced in corners of phase space. These occur, for example, in the jet energy distribution for two jet events near E_J=M_Z/2, the thrust distribution near unity and the jet invariant mass distribution near zero. The extent to which such nonperturbative effects for different observables are related is discussed.Comment: 17 pages. Paper reorganized, and more discussion and results include

Life Course Racism and Depressive Symptoms among Young Black Women

The objective of this study is to evaluate the life course effects of racism on depressive symptoms in young Black women and to identify particularly sensitive periods. Guided by life-course theory and using logistic regression, we analyzed baseline data on racism frequency and stress from racism at two time periods (before age 20 and during the 20s) and follow-up data (at approximate 20-month intervals) on depressive symptoms (using a modified 11-item Center for Epidemiologic Studies Depression Scale, CES-D) among 1612 Black women participants aged 23–34 years living in Detroit, MI. Of the 1612 women, 65% reported experiencing some racism at baseline, and 36.5% had high depressive symptoms at follow-up. Those who experienced high frequency of racism before age 20 had an increased risk for high depressive symptoms (RR = 1.26, 95% CI: 1.07, 1.46) compared to participants in the low racism frequency group. We observed similar associations for high vs. low stress from racism (RR = 1.30, 95% CI : 1.06, 1.54) and high vs. low combination of racism frequency and stress (RR = 1.38, 95% CI: 1.13, 1.64). These findings did not hold or were weaker when assessing racism during the 20s. Among women who experienced high racism across the two time periods, the risk of high depressive symptoms was higher than those who experienced low racism during both periods (RR = 1.49, 95% CI: 1.14, 1.86). The slightly stronger associations between racism and depressive symptoms in childhood and adolescence than in young adulthood suggest that early life might be a sensitive period for experiencing racism

Integrated ultra-thin-film gas sensors

The fabrication and performance of an ultra-thin-film integrated gas sensor for detecting impurities in semiconductor process gases are described. Detector reponses are based on gas-induced resistance changes in an ultra-thin Ti-P film mounted on a thin dielectric window supported by a silicon rim. The window temperature can be shifted several hundred degrees Celsius in less than one second. Gas-induced resistance changes are composed of thermal and Chemical components. The gas concentration and its thermal conductivity determine the thermal contribution, whereas the chemical interactions between the gas and the sensor surface create a superimposed change of resistance, which can be observed when the detector is operated at constant temperature. Pretreament of the as-deposited Ti-Pt thin films under controlled environmental conditions allows tailoring of the electrical, sensing, and microstructural characteristics of the films. One such pretreatment scheme allows the creation of films that, when operated at 150 [deg]C, respond chemically to O2 from 1000 torr down to the 10-7 torr level without any evidence of hysteresis or long-term drift over hundreds of cycles of temperature and gas. There is no chemical response to CF4, which allows detection of sub-ppm levels of O2 in CF4. Temperature-programmed desorption (TPD) of O2 is shown to be a control requirement for dynamic sensing.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/31592/1/0000521.pd

Charming penguin contributions to charmless B decays into two pseudoscalar mesons

We present estimates of the charming penguin contribution to B => K pi, pi pi,K eta, K eta' decays due to intermediate charmed meson states. We find that this contribution is indeed significant for B => K pi decays, and its inclusion, together with the tree and penguin terms, produces large branching ratios in agreement with data, though the analysis is affected by large theoretical uncertainties. On the other hand, for B => pi pi, K eta, K eta' decays, the effect of the charming penguin contribution is more modest. We also compute CP asymmetries for B => K pi, pi pi decays and we obtain rather large results.Comment: 12 pages, 4 figures, LaTeX2e with epsfig. Minor changes in the text, this version will appear in Phys. Rev.

Observing the First Stars and Black Holes

The high sensitivity of JWST will open a new window on the end of the cosmological dark ages. Small stellar clusters, with a stellar mass of several 10^6 M_sun, and low-mass black holes (BHs), with a mass of several 10^5 M_sun should be directly detectable out to redshift z=10, and individual supernovae (SNe) and gamma ray burst (GRB) afterglows are bright enough to be visible beyond this redshift. Dense primordial gas, in the process of collapsing from large scales to form protogalaxies, may also be possible to image through diffuse recombination line emission, possibly even before stars or BHs are formed. In this article, I discuss the key physical processes that are expected to have determined the sizes of the first star-clusters and black holes, and the prospect of studying these objects by direct detections with JWST and with other instruments. The direct light emitted by the very first stellar clusters and intermediate-mass black holes at z>10 will likely fall below JWST's detection threshold. However, JWST could reveal a decline at the faint-end of the high-redshift luminosity function, and thereby shed light on radiative and other feedback effects that operate at these early epochs. JWST will also have the sensitivity to detect individual SNe from beyond z=10. In a dedicated survey lasting for several weeks, thousands of SNe could be detected at z>6, with a redshift distribution extending to the formation of the very first stars at z>15. Using these SNe as tracers may be the only method to map out the earliest stages of the cosmic star-formation history. Finally, we point out that studying the earliest objects at high redshift will also offer a new window on the primordial power spectrum, on 100 times smaller scales than probed by current large-scale structure data.Comment: Invited contribution to "Astrophysics in the Next Decade: JWST and Concurrent Facilities", Astrophysics & Space Science Library, Eds. H. Thronson, A. Tielens, M. Stiavelli, Springer: Dordrecht (2008

Intrauterine devices and endometrial cancer risk : a pooled analysis of the Epidemiology of Endometrial Cancer Consortium

Intrauterine devices (IUDs), long-acting and reversible contraceptives, induce a number of immunological and biochemical changes in the uterine environment that could affect endometrial cancer (EC) risk. We addressed this relationship through a pooled analysis of data collected in the Epidemiology of Endometrial Cancer Consortium. We combined individual-level data from 4 cohort and 14 case-control studies, in total 8,801 EC cases and 15,357 controls. Using multivariable logistic regression, we estimated pooled odds ratios (pooled-ORs) and 95% confidence intervals (CIs) for EC risk associated with ever use, type of device, ages at first and last use, duration of use and time since last use, stratified by study and adjusted for confounders. Ever use of IUDs was inversely related to EC risk (pooled-OR = 0.81, 95% CI = 0.74-0.90). Compared with never use, reduced risk of EC was observed for inert IUDs (pooled-OR = 0.69, 95% CI = 0.58-0.82), older age at first use (≥35 years pooled-OR = 0.53, 95% CI = 0.43-0.67), older age at last use (≥45 years pooled-OR = 0.60, 95% CI = 0.50-0.72), longer duration of use (≥10 years pooled-OR = 0.61, 95% CI = 0.52-0.71) and recent use (within 1 year of study entry pooled-OR = 0.39, 95% CI = 0.30-0.49). Future studies are needed to assess the respective roles of detection biases and biologic effects related to foreign body responses in the endometrium, heavier bleeding (and increased clearance of carcinogenic cells) and localized hormonal changes