Spectral irradiance of total and spectral energy standards

Spectral irradiance measurements of tungsten and carbon filament lamps for energy standards and accuracy limits used in space simulator

Cardinality versus q-Norm Constraints for Index Tracking

Index tracking aims at replicating a given benchmark with a smaller number of its constituents. Different quantitative models can be set up to determine the optimal index replicating portfolio. In this paper, we propose an alternative based on imposing a constraint on the q-norm, 0 < q < 1, of the replicating portfolios’ asset weights: the q-norm constraint regularises the problem and identifies a sparse model. Both approaches are challenging from an optimisation viewpoint due to either the presence of the cardinality constraint or a non-convex constraint on the q-norm. The problem can become even more complex when non-convex distance measures or other real-world constraints are considered. We employ a hybrid heuristic as a flexible tool to tackle both optimisation problems. The empirical analysis on real-world financial data allows to compare the two index tracking approaches. Moreover, we propose a strategy to determine the optimal number of constituents and the corresponding optimal portfolio asset weights

Aerosol and cloud sensing with the Lidar In-space Technology Experiment (LITE)

The Lidar In-space Technology Experiment (LITE) is a multi-wavelength backscatter lidar developed by NASA Langley Research Center to fly on the Space Shuttle. The LITE instrument is built around a three-wavelength ND:YAG laser and a 1-meter diameter telescope. The laser operates at 10 Hz and produces about 500 mJ per pulse at 1064 nm and 532 nm, and 150 mJ per pulse at 355 nm. The objective of the LITE program is to develop the engineering processes required for space lidar and to demonstrate applications of space-based lidar to remote sensing of the atmosphere. The LITE instrument was designed to study a wide range of cloud and aerosol phenomena. To this end, a comprehensive program of scientific investigations has been planned for the upcoming mission. Simulations of on-orbit performance show the instrument has sufficient sensitivity to detect even thin cirrus on a single-shot basis. Signal averaging provides the capability of measuring the height and structure of the planetary boundary layer, aerosols in the free troposphere, the stratospheric aerosol layer, and density profiles to an altitude of 40 km. The instrument has successfully completed a ground-test phase and is scheduled to fly on the Space Shuttle Discovery for a 9-day mission in September 1994

Vertical Profiles of Aerosol Optical Properties Over Central Illinois and Comparison with Surface and Satellite Measurements

Between June 2006 and September 2009, an instrumented light aircraft measured over 400 vertical profiles of aerosol and trace gas properties over eastern and central Illinois. The primary objectives of this program were to (1) measure the in situ aerosol properties and determine their vertical and temporal variability and (2) relate these aircraft measurements to concurrent surface and satellite measurements. Underflights of the CALIPSO satellite show reasonable agreement in a majority of retrieved profiles between aircraft-measured extinction at 532 nm (adjusted to ambient relative humidity) and CALIPSO-retrieved extinction, and suggest that routine aircraft profiling programs can be used to better understand and validate satellite retrieval algorithms. CALIPSO tended to overestimate the aerosol extinction at this location in some boundary layer flight segments when scattered or broken clouds were present, which could be related to problems with CALIPSO cloud screening methods. The in situ aircraft-collected aerosol data suggest extinction thresholds for the likelihood of aerosol layers being detected by the CALIOP lidar. These statistical data offer guidance as to the likelihood of CALIPSO's ability to retrieve aerosol extinction at various locations around the globe

Optimization Heuristics for Determining Internal Rating Grading Scales

Basel II imposes regulatory capital on banks related to the default risk of their credit portfolio. Banks using an internal rating approach compute the regulatory capital from pooled probabilities of default. These pooled probabilities can be calculated by clustering credit borrowers into different buckets and computing the mean PD for each bucket. The clustering problem can become very complex when Basel II regulations and real-world constraints are taken into account. Search heuristics have already proven remarkable performance in tackling this problem. A Threshold Accepting algorithm is proposed, which exploits the inherent discrete nature of the clustering problem. This algorithm is found to outperform alternative methodologies already proposed in the literature, such as standard k-means and Differential Evolution. Besides considering several clustering objectives for a given number of buckets, we extend the analysis further by introducing new methods to determine the optimal number of buckets in which to cluster banks’ clients

Aryltetralin lignans from Hyptis brachiata inhibiting T lymphocyte proliferation

Increased activation and proliferation of T lymphocytes plays an essential role in the development of chronic inflammation and autoimmune diseases. Currently used immunosuppressive drugs often do not provide long-lasting relief of symptoms and show a gradual loss of efficacy over time, and are accompanied by various side effects. Therefore, novel immunosuppressive lead substances are needed. For this purpose, an in-house library consisting of 600 extracts of plants from Panama was screened for inhibition of human T lymphocyte proliferation. As one of the hits, an ethyl acetate extract from the aerial parts of Hyptis brachiata (Lamiaceae) exhibited strong inhibitory effects. Subsequent investigation resulted in the isolation of seven aryltetralin lignans, five arylnaphthalene lignans, two flavonoids, three triterpenes, and cinnamyl cinnamate. Aryltetralin lignans inhibited T lymphocyte proliferation in a concentration-dependent manner without induction of apoptosis. No relevant inhibition was observed for the arylnaphthalene lignans, flavonoids, and triterpenes. Additional cell cycle arrest investigations revealed that isolated aryltetralin lignans potently inhibited cell division in G2/M phase similarly to podophyllotoxin. Multifluorescence panel analyses of the extract also showed weak suppressive effects on the production of IL-2 and TNF-α. Therefore, preparations made out of H. brachiata could be further explored as an interesting herbal alternative in the treatment of autoimmune diseases

Title: will be set by the publisher Editors: will be set by the publisher EAS Publications Series, Vol.?, 2009 THE BEST SITE ON EARTH?

Abstract. We compare the merits of potential observatory sites on the Antarctic Plateau, in regard to the boundary layer, cloud cover, free atmosphere seeing, aurorae, airglow, and precipitable water vapour. We find that (a) all Antarctic sites are likely compromised for optical work by airglow and aurorae; (b) Dome A is the best existing site in almost all respects; (c) there is an even better site (‘Ridge A’) 150kms SW of Dome A; (d) Dome F is a remarkably good site except for aurorae; (e) Dome C probably has the least cloud cover of any of the sites, and might be able to use a predicted ‘OH hole ’ in the Spring. The Antarctic plateau probably contains the best astronomical sites on Earth, but none of the existing bases were situated with astronomy in mind. In Saunders et al.(2009), we use published data and models, and unpublished meteorological and other information, to try to compare the merits of the potential sites. Here, we summarise only the new findings and conclusions. We include boundary layer thickness, cloud cover, auroral emission, airglow, precipitable water vapour, an