Building from the Ground Up: Creating Effective Programs to Mentor Children of Prisoners (The Amachi Model)

Drawing from P/PVs five years of hands-on experience designing and implementing Amachi programs around the country, Building From The Ground Up describes best practices for planning, developing and managing a mentoring-children-of-prisoners program. This guidebook is essential for learning the professional procedures, standards and administrative tools required to have an effective program

A dynamic spatial model of conflict escalation

In both historical and modern conflicts, space plays a critical role in how interactions occur over time. Despite its importance, the spatial distribution of adversaries has often been neglected in mathematical models of conflict. In this paper, we propose an entropy-maximising spatial interaction method for disaggregating the impact of space, employing a general notion of ‘threat’ between two adversaries. This approach addresses a number of limitations that are associated with partial differential equation approaches to spatial disaggregation. We use this method to spatially disaggregate the Richardson model of conflict escalation, and then explore the resulting model with both analytical and numerical treatments. A bifurcation is identified that dramatically influences the resulting spatial distribution of conflict and is shown to persist under a range of model specifications. Implications of this finding for real-world conflicts are discussed

The structure of the RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sites

The multi-protein complex WRAD, formed by WDR5, RbBP5, Ash2L and Dpy30, binds to the MLL SET domain to stabilize the catalytically active conformation required for histone H3K4 methylation. In addition, the WRAD complex contributes to the targeting of the activated complex to specific sites on chromatin. RbBP5 is central to MLL catalytic activation, by making critical contacts with the other members of the complex. Interestingly its only major structural domain, a canonical WD40 repeat -propeller, is not implicated in this function. Here, we present the structure of the RbBP5 -propeller domain revealing a distinct, feature rich surface, dominated by clusters of Arginine residues. Our nuclear magnetic resonance binding data supports the hypothesis that in addition to the role of RbBP5 in catalytic activation, its -propeller domain is a platform for the recruitment of the MLL complexes to chromatin targets through its direct interaction with nucleic acids

The Ursinus Weekly, March 18, 1963

Future of the United Nations topic of speaker Bohmrich in April • Pre-medicals see childbirth films • Stayer & Campbell representatives to all-state band • Chemistry profs to gather at UC for convention • UC students invited to attend banquet of local businessmen • Pettit appears at Controversy chat • Sharon Robbins named editor-in-chief of Weekly; Hunter, Peek, Garner selected as staff editors • Campus Chest drive extended for week • Navy information team to visit campus soon • Gordon lectures on archaeology in Forum program • Junior Prom slated for April 5 • Social Security agent to interview students • Carlton Dingman plans to attend University of Sweden next year • Young Republicans see film on parties • Montgomery County science fair to be held at UC later this month • Helfferich plans to attend Navy orientation cruise • Editorial: This is it! • Progress on freshman term papers in various stages in Rimby\u27s dorm • Letters to the editor • Student-faculty show Saturday termed success of high quality • Freedom to learn topic of PSEA film • Intramural wrestling tournament produces 5 champions from 5 teams • Baseball prospects are encouraging • Trackmen optimistic about Spring season • IM basketball title game tomorrow pits Maples against Leber-South • Netwomen finish season with loss to West Chesterhttps://digitalcommons.ursinus.edu/weekly/1291/thumbnail.jp