First asymmetric synthesis of the natural enantiomer of the indolizidino[8,7-b]indole alkaloid harmicine

We report a novel, facile and asymmetric approach for the synthesis of the indole alkaloid harmicine via a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step, and verify the relative stereochemistry of the key synthetic intermediate in this approach through X-ray crystallography

A formal asymmetric synthesis of both enantiomers of the Erythrina Alkaloid 3-Demethoxyerythratidinone

A formal asymmetric synthesis of both enantiomers of the Erythrina alkaloid 3- demethoxyerythratidinone is reported through the application of a highly functionalised lactam template as an N-acyliminium precursor

A new asymmetric synthesis of the anti-tumour alkaloid (R)-(+)-crispine A

We report a novel, facile and asymmetric approach for the synthesis of the anti-tumour alkaloid (+)-crispine A via a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step