70 research outputs found
Galilean and Dynamical Invariance of Entanglement in Particle Scattering
Particle systems admit a variety of tensor product structures (TPSs)
depending on the algebra of observables chosen for analysis. Global symmetry
transformations and dynamical transformations may be resolved into local
unitary operators with respect to certain TPSs and not with respect to others.
Symmetry-invariant and dynamical-invariant TPSs are defined and various notions
of entanglement are considered for scattering states.Comment: 4 pages, no figures; v.3 has typos corrected, a new reference, and a
revised conclusio
Complex Energies and Beginnings of Time Suggest a Theory of Scattering and Decay
Many useful concepts for a quantum theory of scattering and decay (like
Lippmann-Schwinger kets, purely outgoing boundary conditions, exponentially
decaying Gamow vectors, causality) are not well defined in the mathematical
frame set by the conventional (Hilbert space) axioms of quantum mechanics.
Using the Lippmann-Schwinger equations as the takeoff point and aiming for a
theory that unites resonances and decay, we conjecture a new axiom for quantum
mechanics that distinguishes mathematically between prepared states and
detected observables. Suggested by the two signs of the
Lippmann-Schwinger equations, this axiom replaces the one Hilbert space of
conventional quantum mechanics by two Hardy spaces. The new Hardy space theory
automatically provides Gamow kets with exponential time evolution derived from
the complex poles of the -matrix. It solves the causality problem since it
results in a semigroup evolution. But this semigroup brings into quantum
physics a new concept of the semigroup time , a beginning of time. Its
interpretation and observations are discussed in the last section.Comment: 27 pages, 3 figure
Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts
BACKGROUND: Osteosarcoma (OSA) is the most common primary bone tumor of dogs and carries a poor prognosis despite aggressive treatment. An improved understanding of the biology of OSA is critically needed to allow for development of novel diagnostic, prognostic, and therapeutic tools. The surface-exposed proteome (SEP) of a cancerous cell includes a multifarious array of proteins critical to cellular processes such as proliferation, migration, adhesion, and inter-cellular communication. The specific aim of this study was to define a SEP profile of two validated canine OSA cell lines and a normal canine osteoblast cell line utilizing a biotinylation/streptavidin system to selectively label, purify, and identify surface-exposed proteins by mass spectrometry (MS) analysis. Additionally, we sought to validate a subset of our MS-based observations via quantitative real-time PCR, Western blot and semi-quantitative immunocytochemistry. Our hypothesis was that MS would detect differences in the SEP composition between the OSA and the normal osteoblast cells. RESULTS: Shotgun MS identified 133 putative surface proteins when output from all samples were combined, with good consistency between biological replicates. Eleven of the MS-detected proteins underwent analysis of gene expression by PCR, all of which were actively transcribed, but varied in expression level. Western blot of whole cell lysates from all three cell lines was effective for Thrombospondin-1, CYR61 and CD44, and indicated that all three proteins were present in each cell line. Semi-quantitative immunofluorescence indicated that CD44 was expressed at much higher levels on the surface of the OSA than the normal osteoblast cell lines. CONCLUSIONS: The results of the present study identified numerous differences, and similarities, in the SEP of canine OSA cell lines and normal canine osteoblasts. The PCR, Western blot, and immunocytochemistry results, for the subset of proteins evaluated, were generally supportive of the mass spectrometry data. These methods may be applied to other cell lines, or other biological materials, to highlight unique and previously unrecognized differences between samples. While this study yielded data that may prove useful for OSA researchers and clinicians, further refinements of the described techniques are expected to yield greater accuracy and produce a more thorough SEP analysis
The rigged Hilbert space approach to the Lippmann-Schwinger equation. Part II: The analytic continuation of the Lippmann-Schwinger bras and kets
The analytic continuation of the Lippmann-Schwinger bras and kets is obtained
and characterized. It is shown that the natural mathematical setting for the
analytic continuation of the solutions of the Lippmann-Schwinger equation is
the rigged Hilbert space rather than just the Hilbert space. It is also argued
that this analytic continuation entails the imposition of a time asymmetric
boundary condition upon the group time evolution, resulting into a semigroup
time evolution. Physically, the semigroup time evolution is simply a (retarded
or advanced) propagator.Comment: 32 pages, 3 figure
Non-Linear Canonical Transformations in Classical and Quantum Mechanics
-Mechanics is a consistent physical theory which describes both classical
and quantum mechanics simultaneously through the representation theory of the
Heisenberg group. In this paper we describe how non-linear canonical
transformations affect -mechanical observables and states. Using this we
show how canonical transformations change a quantum mechanical system. We seek
an operator on the set of -mechanical observables which corresponds to the
classical canonical transformation. In order to do this we derive a set of
integral equations which when solved will give us the coherent state expansion
of this operator. The motivation for these integral equations comes from the
work of Moshinsky and a variety of collaborators. We consider a number of
examples and discuss the use of these equations for non-bijective
transformations.Comment: The paper has been improved in light of a referee's report. The paper
will appear in the Journal of Mathematical Physics. 24 pages, no figure
On the inconsistency of the Bohm-Gadella theory with quantum mechanics
The Bohm-Gadella theory, sometimes referred to as the Time Asymmetric Quantum
Theory of Scattering and Decay, is based on the Hardy axiom. The Hardy axiom
asserts that the solutions of the Lippmann-Schwinger equation are functionals
over spaces of Hardy functions. The preparation-registration arrow of time
provides the physical justification for the Hardy axiom. In this paper, it is
shown that the Hardy axiom is incorrect, because the solutions of the
Lippmann-Schwinger equation do not act on spaces of Hardy functions. It is also
shown that the derivation of the preparation-registration arrow of time is
flawed. Thus, Hardy functions neither appear when we solve the
Lippmann-Schwinger equation nor they should appear. It is also shown that the
Bohm-Gadella theory does not rest on the same physical principles as quantum
mechanics, and that it does not solve any problem that quantum mechanics cannot
solve. The Bohm-Gadella theory must therefore be abandoned.Comment: 16 page
Symmetry Representations in the Rigged Hilbert Space Formulation of Quantum Mechanics
We discuss some basic properties of Lie group representations in rigged
Hilbert spaces. In particular, we show that a differentiable representation in
a rigged Hilbert space may be obtained as the projective limit of a family of
continuous representations in a nested scale of Hilbert spaces. We also
construct a couple of examples illustrative of the key features of group
representations in rigged Hilbert spaces. Finally, we establish a simple
criterion for the integrability of an operator Lie algebra in a rigged Hilbert
space
Understanding entangled spins in QED
The stability of two entangled spins dressed by electrons is studied by
calculating the scattering phase shifts. The interaction between electrons is
interpreted by fully relativistic QED and the screening effect is described
phenomenologically in the Debye exponential form . Our results
show that if the (Einstein-Podolsky-Rosen-) EPR-type states are kept stable
under the interaction of QED, the spatial wave function must be
parity-dependent. The spin-singlet state and the polarized state along the z-axis\QTR{bf}{\}give rise to two
different kinds of phase shifts\QTR{bf}{.} Interestingly, the interaction
between electrons in the spin-singlet pair is found to be attractive. Such an
attraction could be very useful when we extract the entangled spins from
superconductors. A mechanism to filter the entangled spins is also discussed.Comment: 6 pages, 3 figures. changes adde
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