Trauma-Informed Training for Educators

The occurrence of childhood trauma in the school setting is an ongoing and pervasive issue. Students impacted by trauma frequently display challenging and problematic behavior, and educators lack the trauma-informed care needed to help them heal. These students often go untreated, and their trauma continues to impact them and those around them. This project aims to review the current literature on childhood trauma and how educators can better support students affected by trauma. The trauma-informed training associated with this project will offer tools, curricula, and resources that educators can implement on their campuses

Junior Recital:Kristin White, Mezzo-Soprano

Kemp Recital Hall Saturday Afternoon November 22, 1997 4:00p.m

Senior Recital:Kristin Lynn White, Soprano

Kemp Recital Hall Friday Evening April 21, 2000 8:30 p.m

Graduate Recital:Kristin Lynn White, Soprano

Kemp Recital Hall Sunday Noon April 27, 2008 12:00p.m

Construction of an in vitro bistable circuit from synthetic transcriptional switches

Information processing using biochemical circuits is essential for survival and reproduction of natural organisms. As stripped-down analogs of genetic regulatory networks in cells, we engineered artificial transcriptional networks consisting of synthetic DNA switches, regulated by RNA signals acting as transcription repressors, and two enzymes, bacteriophage T7 RNA polymerase and Escherichia coli ribonuclease H. The synthetic switch design is modular with programmable connectivity and allows dynamic control of RNA signals through enzyme-mediated production and degradation. The switches support sharp and adjustable thresholds using a competitive hybridization mechanism, allowing arbitrary analog or digital circuits to be created in principle. As an example, we constructed an in vitro bistable memory by wiring together two synthetic switches and performed a systematic quantitative characterization. Good agreement between experimental data and a simple mathematical model was obtained for switch input/output functions, phase plane trajectories, and the bifurcation diagram for bistability. Construction of larger synthetic circuits provides a unique opportunity for evaluating model inference, prediction, and design of complex biochemical systems and could be used to control nanoscale devices and artificial cells

Adult Patrons' Use of Public Libraries to Find Health Information

The need for health information is universal, but with limited time to spend with health care professionals and the increasing amount of health information available online, people often have trouble finding quality health information that they can understand. Public libraries are perhaps a solution to this problem, as they provide access to resources and help with searching for information. This study seeks to understand how people use public libraries for finding health information. Patrons from three libraries were surveyed about their reasons for choosing the public library to find health information, the types of resources they used while there, and their satisfaction level with the information they found. Reference librarians were interviewed about the services they provide and the types of resources available to users. Findings indicate that most users come to the public library to use medical books available there and that many prefer print sources over online sources

Results of a reevaluation of cardiovascular outcomes in the RECORD trial

Background The US Food and Drug Administration (FDA) required a reevaluation of cardiovascular (CV) outcomes in the RECORD trial. This provided an opportunity to assess the implications of event adjudication by 2 groups and quantify the differences as well as to use new FDA end point definitions in development.<p></p> Methods Original data were used to systematically identify all potential deaths, myocardial infarctions (MIs), and strokes. Site investigators were approached for additional source documents and information about participants lost to follow-up. Suspected events were adjudicated using standard procedures, and the results were compared with the original trial outcomes.<p></p> Results Follow-up for mortality was 25,833 person-years, including an additional 328 person-years identified during the reevaluation effort. A total of 184 CV or unknown-cause deaths (88 rosiglitazone, 96 metformin/sulfonylurea), 128 participants with an MI (68 rosiglitazone, 60 metformin/sulfonylurea), and 113 participants with a stroke (50 rosiglitazone, 63 metformin/sulfonylurea) were included. The hazard ratio (HR) for rosiglitazone versus metformin/sulfonylurea for the end point of CV (or unknown cause) death, MI, or stroke was 0.95 (95% CI 0.78-1.17) compared with 0.93 (95% CI 0.74-1.15) for the original RECORD results. Treatment comparisons for MI (HR 1.13, 95% CI 0.80-1.59) and mortality (HR 0.86, 95% CI 0.68-1.08) were also the same compared with the original RECORD results. Sensitivity analyses were also consistent with the original RECORD results. Analyses using the FDA definitions showed similar results.<p></p> Conclusions Only a modest number of additional person-years of follow-up were ascertained from this reevaluation of CV end points in RECORD. Observed HRs and CIs from these analyses using the original RECORD or new FDA end point definitions showed similar treatment effects of rosiglitazone compared with the original RECORD results.<p></p&gt