561 research outputs found
Mate familiarity and social learning in a monogamous lizard
Social learning is thought to be advantageous as it allows an animal to gather information quickly without engaging in costly trial-and-error learning. However, animals should be selective about when and whom they learn from. Familiarity is predicted to positively inluence an animal’s reliance on social learning; yet, few studies have empirically tested this theory. We used a lizard (Liopholis whitii) that forms long-term monogamous pair bonds to examine the efects of partner familiarity on social learning in two novel foraging tasks, an association and reversal task. We allowed female lizards to observe trained conspeciics that were either familiar (social mate) or unfamiliar execute these tasks and compared these two groups with control females that did not receive social information. Lizards preferentially relied on trial-and-error learning in the association task. In the reversal task, lizards that were demonstrated by familiar partners learnt in fewer trials compared to control lizards and made more correct choices. Our results provide some evidence for context-dependent learning with lizards diferentiating between when they utilize social learning, and, to a limited degree, whom they learnt from. Understanding the role of the social context in which learning occurs provides important insight into the beneits of social learning and sociality more generally
Premature death among primary care patients with a history of self-harm
PURPOSE Self-harm is a public health problem that requires a better understanding of mortality risk. We undertook a study to examine premature mortality in a nationally representative cohort of primary care patients who had harmed themselves.
METHODS During 2001–2013, a total of 385 general practices in England contributed data to the Clinical Practice Research Datalink with linkage to Office for National Statistics mortality records. We identified 30,017 persons aged 15 to 64 years with a recorded episode of self-harm. We estimated the relative risks of all-cause and cause-specific natural and unnatural mortality using a comparison cohort of 600,258 individuals matched on age, sex, and general practice.
RESULTS We found an elevated risk of dying prematurely from any cause among the self-harm cohort, especially in the first year of follow-up (adjusted hazard ratio for that year, 3.6; 95% CI, 3.1–4.2). In particular, suicide risk was especially high during the first year (adjusted hazard ratio, 54.4; 95% CI, 34.3–86.3); although it declined sharply, it remained much higher than that in the comparison cohort. Large elevations of risk throughout the follow-up period were also observed for accidental, alcohol-related, and drug poisoning deaths. At 10 years of follow-up, cumulative incidence values were 6.5% (95% CI, 6.0%–7.1%) for all-cause mortality and 1.3% (95% CI, 1.2%–1.5%) for suicide.
CONCLUSIONS Primary care patients who have harmed themselves are at greatly increased risk of dying prematurely by natural and unnatural causes, and especially within a year of a first episode. These individuals visit clinicians at a relatively high frequency, which presents a clear opportunity for preventive action. Primary care patients with myriad comorbidities, including self-harming behavior, mental disorder, addictions, and physical illnesses, will require concerted, multipronged, multidisciplinary collaborative care approaches
Evaluating case studies of community-oriented integrated care.
This paper summarises a ten-year conversation within London Journal of Primary Care about the nature of community-oriented integrated care (COIC) and how to develop and evaluate it. COIC means integration of efforts for combined disease-treatment and health-enhancement at local, community level. COIC is similar to the World Health Organisation concept of a Community-Based Coordinating Hub - both require a local geographic area where different organisations align their activities for whole system integration and develop local communities for health. COIC is a necessary part of an integrated system for health and care because it enables multiple insights into 'wicked problems', and multiple services to integrate their activities for people with complex conditions, at the same time helping everyone to collaborate for the health of the local population. The conversation concludes seven aspects of COIC that warrant further attention
State enrolment and energy-carbon transitions: syndromic experimentation and atomisation in England
This article analyses how national governments seek to enrol different subjects and objects in energy-carbon restructuring. It takes analysis beyond consideration of particular subjectivities and governmentalities to consider an expanded range of objects and subjects of governing at a distance. Developing an analytical model of ‘modes of enrolment’ focusing on power modalities, forms of policy integration and policy targets, the article explores five broad modes of enrolment employed in England. The article shows how policy across all modes of enrolment in England has increasingly tended towards disordered, syndromic experimentation and government by-project rather than any systematic programme of government
Finding the niche: A review of market assessment methodologies for rural electrification with small scale wind power
The mass roll out of solar PV across the Global South has enabled electricity access for millions of people. In the right context, Small Wind Turbines (SWTs) can be complementary, offering the potential to generate at times of low solar resource (night, monsoon season, winter, etc.) and increasing the proportion of the total energy system that can be manufactured locally. However, many contextual factors critically affect the viability of the technology, such as the extreme variability in the wind resource itself and the local availability of technical support. Therefore, performing a detailed market analysis in each new context is much more important. The Wind Empowerment Market Assessment Methodology (WEMAM) is a multi-scalar, transdisciplinary methodology for identifying the niche contexts where small wind can make a valuable contribution to rural electrification. This paper aims to inform the development of WEMAM with a critical review of existing market assessment methodologies. By breaking down WEMAM into its component parts, reflecting upon its practical applications to date and drawing upon insights from the literature, opportunities where it could continue to evolve are highlighted. Key opportunities include shifting the focus towards development outcomes; creating community archetypes; localised studies in high potential regions; scenario modelling and MCDA ranking of proposed interventions; participatory market mapping; and applying socio-technical transitions theory to understand how the small wind niche can break through into the mainstream
Improving Many-Objective Evolutionary Algorithms by Means of Edge-Rotated Cones
Given a point in -dimensional objective space, any -ball of a
point can be partitioned into the incomparable, the dominated and dominating
region. The ratio between the size of the incomparable region, and the
dominated (and dominating) region decreases proportionally to ,
i.e., the volume of the Pareto dominating orthant as compared to all other
volumes. Due to this reason, it gets increasingly unlikely that dominating
points can be found by random, isotropic mutations. As a remedy to stagnation
of search in many objective optimization, in this paper, we suggest to enhance
the Pareto dominance order by involving an obtuse convex dominance cone in the
convergence phase of an evolutionary optimization algorithm. We propose
edge-rotated cones as generalizations of Pareto dominance cones for which the
opening angle can be controlled by a single parameter only. The approach is
integrated in several state-of-the-art multi-objective evolutionary algorithms
(MOEAs) and tested on benchmark problems with four, five, six and eight
objectives. Computational experiments demonstrate the ability of these
edge-rotated cones to improve the performance of MOEAs on many-objective
optimization problems
Pain assessment for people with dementia: a systematic review of systematic reviews of pain assessment tools.
BACKGROUND: There is evidence of under-detection and poor management of pain in patients with dementia, in both long-term and acute care. Accurate assessment of pain in people with dementia is challenging and pain assessment tools have received considerable attention over the years, with an increasing number of tools made available. Systematic reviews on the evidence of their validity and utility mostly compare different sets of tools. This review of systematic reviews analyses and summarises evidence concerning the psychometric properties and clinical utility of pain assessment tools in adults with dementia or cognitive impairment. METHODS: We searched for systematic reviews of pain assessment tools providing evidence of reliability, validity and clinical utility. Two reviewers independently assessed each review and extracted data from them, with a third reviewer mediating when consensus was not reached. Analysis of the data was carried out collaboratively. The reviews were synthesised using a narrative synthesis approach. RESULTS: We retrieved 441 potentially eligible reviews, 23 met the criteria for inclusion and 8 provided data for extraction. Each review evaluated between 8 and 13 tools, in aggregate providing evidence on a total of 28 tools. The quality of the reviews varied and the reporting often lacked sufficient methodological detail for quality assessment. The 28 tools appear to have been studied in a variety of settings and with varied types of patients. The reviews identified several methodological limitations across the original studies. The lack of a 'gold standard' significantly hinders the evaluation of tools' validity. Most importantly, the samples were small providing limited evidence for use of any of the tools across settings or populations. CONCLUSIONS: There are a considerable number of pain assessment tools available for use with the elderly cognitive impaired population. However there is limited evidence about their reliability, validity and clinical utility. On the basis of this review no one tool can be recommended given the existing evidence
Identification of Radiopure Titanium for the LZ Dark Matter Experiment and Future Rare Event Searches
The LUX-ZEPLIN (LZ) experiment will search for dark matter particle
interactions with a detector containing a total of 10 tonnes of liquid xenon
within a double-vessel cryostat. The large mass and proximity of the cryostat
to the active detector volume demand the use of material with extremely low
intrinsic radioactivity. We report on the radioassay campaign conducted to
identify suitable metals, the determination of factors limiting radiopure
production, and the selection of titanium for construction of the LZ cryostat
and other detector components. This titanium has been measured with activities
of U~1.6~mBq/kg, U~0.09~mBq/kg,
Th~~mBq/kg, Th~~mBq/kg, K~0.54~mBq/kg, and Co~0.02~mBq/kg (68\% CL).
Such low intrinsic activities, which are some of the lowest ever reported for
titanium, enable its use for future dark matter and other rare event searches.
Monte Carlo simulations have been performed to assess the expected background
contribution from the LZ cryostat with this radioactivity. In 1,000 days of
WIMP search exposure of a 5.6-tonne fiducial mass, the cryostat will contribute
only a mean background of (stat)(sys) counts.Comment: 13 pages, 3 figures, accepted for publication in Astroparticle
Physic
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