917 research outputs found

    Securities Law Duties of Bond Counsel

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    Laparoscopic Cholecystectomy: Incidental Carcinoma of the Gallbladder with Abdominal Wall and Axillary Node Metastasis

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    A case report is presented of intra-mural gallbladder carcinoma discovered incidentally after laparoscopic cholecystectomy who subsequently developed abdominal wall recurrence at the epigastric exit port, and axillary lymph node metastases. Possible preventative steps for tumour dissemination and a management plan if incidental carcinoma is diagnosed is discussed. The use of a non-porous retrieval bag, early recognition of the carcinoma and excision of the exit wound are advocated

    A phase II trial of aclacinomycin-A in advanced squamous cell carcinoma of the head and neck

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    Sixteen patients with advanced squamous cell carcinoma of the head and neck were entered into a phase II trial of Aclacinomycin-A (ACM), 100 mg/M 2 administered by brief infusion every three weeks. All patients had received prior radiation therapy and prior non-anthracycline containing chemotherapy. No clinically significant disease regression was observed in fourteen patients having adequate trials. The major toxicity was myelosuppression; leukopenia occurred in 93% of patients. Gastro-intestinal toxicity was mild and included two patients with transient liver function test abnormalities. No antitumor activity was observed in this patient population which was heavily pre-treated and had a median Karnofsky performance status of only 60%. The results of other phase II trials of ACM-A have been similarly disappointing suggesting that it is not a clinically useful agent in the treatment of solid tumors.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45289/1/10637_2004_Article_BF00170763.pd

    Ammonia Emission, Manure Nutrients and Egg Production of Laying Hens Fed Distiller Dried Grain Diets

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    A USDA Natural Resources Conservation Service, Conservation Innovation Grant project coordinated by the United Egg Producers (UEP) conducted concurrent demonstrations in Iowa and Pennsylvania (PA) at commercial laying hen facilities. The goal was to document manure nutrient and gas emission improvements through the use of dried distiller’s grain with solubles (DDGS) diets and/or other dietary modifications while maintaining or improving hen productivity. Results of the PA trial are presented here. Diets containing 10% corn DDGS with (D+P) or without (D) the probiotic Provalen™ were compared to a corn-soybean based control diet (CON). The isocaloric, amino acid balanced diets were fed to three groups of 39,800 Lohmann hens in one house. Hens were 20-65 wk of age with each diet provided to 2 of 6 rows of stacked cages with manure belts (six decks high). Feed intake, water consumption, hen body weight (BW), egg production (EP,) egg case weight, mortality, feed cost (FC), and egg income (EI) were provided weekly by the cooperating egg company. Replicated monthly data, including egg weight (EW), albumen height (AH), Haugh units (HU), yolk color (YC), shell strength (SS) and shell thickness (ST), were determined from eggs collected from six 4-cage sections of hens on each diet. Replicated monthly samples of hen manure (fresh and from storage) were analyzed for moisture and major nutrients. Ammonia (NH3) gas measurements utilized a non-steady state flux chamber method coupled with photoacoustic infrared gas analyzer. There was no clear trend in the magnitude of NH3 emissions relative to the diets within the hen house as measured on the manure belt. At 32 and 36 wks of age, NH3 emissions were significantly (P \u3c 0.10) higher in D while D+P and CON were lower and similar. At 48 and 52 wks, NH3 emissions from D were similar to D+P and significantly lower than CON. Emission rate from belt manure averaged 0.42 ±0.025 g bird-1 d-1 for all treatments and dates. There was no significant impact of diet on BW, EW, HU, SS, or ST (P =0.10 to 0.66), however, CON hens had lower EP, AH, and YC compared to D and D+P hens (P=0.05). Fresh manure total phosphorus (P2O5) was higher for CON samples (P \u3c 0.05) while other major agronomic nutrients and moisture were not significantly different among treatments. Stored CON manure samples had increased moisture and NH4-N compared to those of D and D+P treatments (P \u3c 0.10). Weekly EI minus FC averaged 6,146,6,146, 6,215, and $6,209 for the CON, D, and D+P diets, respectively
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