ホメオボックスタンパク質 NKX6.1 による interleukin-6 の発現上昇を介したBasal-like乳癌細胞の増殖制御機構

京都大学0048新制・課程博士博士(医学)甲第19930号医博第4150号新制||医||1017(附属図書館)33016京都大学大学院医学研究科医学専攻(主査)教授 野田 亮, 教授 小川 誠司, 教授 高田 穣学位規則第4条第1項該当Doctor of Medical ScienceKyoto UniversityDFA

Mapping California Rice Using Optical and SAR Data Fusion with Phenological Features in Google Earth Engine

California, known for its diverse agriculture, is also a major producer of rice, especially in its northern regions in Sacramento River Valley. Traditional methods, predominantly reliant on optical-based satellite imagery, encounter limitations due to atmospheric interference and sensor resolution. The ability of Synthetic Aperture Radar (SAR) to penetrate atmospheric distortions and exhibit high sensitivity to vegetation structure presents a distinct advantage over optical-based methods. Utilizing Optical and SAR data fusion, this study advances the enhanced pixel-based phenological feature composite (Eppf) method using SVM classification algorithm, which can track phenological changes and patterns, providing valuable insights for agricultural planning and management. We demonstrate that Radar Vegetation Index (RVI) derived from SAR data, offers an improved alternative for identifying and mapping rice fields with enhanced accuracy. Subsequent research will focus on enhancing the suggested approach and investigating its relevance and adaptability to different types of crops

ARF-Plus: Controlling Perceptual Factors in Artistic Radiance Fields for 3D Scene Stylization

The radiance fields style transfer is an emerging field that has recently gained popularity as a means of 3D scene stylization, thanks to the outstanding performance of neural radiance fields in 3D reconstruction and view synthesis. We highlight a research gap in radiance fields style transfer, the lack of sufficient perceptual controllability, motivated by the existing concept in the 2D image style transfer. In this paper, we present ARF-Plus, a 3D neural style transfer framework offering manageable control over perceptual factors, to systematically explore the perceptual controllability in 3D scene stylization. Four distinct types of controls - color preservation control, (style pattern) scale control, spatial (selective stylization area) control, and depth enhancement control - are proposed and integrated into this framework. Results from real-world datasets, both quantitative and qualitative, show that the four types of controls in our ARF-Plus framework successfully accomplish their corresponding perceptual controls when stylizing 3D scenes. These techniques work well for individual style inputs as well as for the simultaneous application of multiple styles within a scene. This unlocks a realm of limitless possibilities, allowing customized modifications of stylization effects and flexible merging of the strengths of different styles, ultimately enabling the creation of novel and eye-catching stylistic effects on 3D scenes

Forecasting Vegetation Health in the MENA Region by Predicting Vegetation Indicators with Machine Learning Models

Machine learning (ML) techniques can be applied to predict and monitor drought conditions due to climate change. Predicting future vegetation health indicators (such as EVI, NDVI, and LAI) is one approach to forecast drought events for hotspots (e.g. Middle East and North Africa (MENA) regions). Recently, ML models were implemented to predict EVI values using parameters such as land types, time series, historical vegetation indices, land surface temperature, soil moisture, evapotranspiration etc. In this work, we collected the MODIS atmospherically corrected surface spectral reflectance imagery with multiple vegetation related indices for modeling and evaluation of drought conditions in the MENA region. These models are built by a total of 4556 and 519 normalized samples for training and testing purposes, respectively and with 51820 samples used for model evaluation. Models such as multilinear regression, penalized regression models, support vector regression (SVR), neural network, instance-based learning K-nearest neighbor (KNN) and partial least squares were implemented to predict future values of EVI. The models show effective performance in predicting EVI values (R2\u3e 0.95) in the testing and (R2\u3e 0.93) in the evaluation process

Evaluating Future Water Availability in Texas through the Lens of a Data-Driven Approach Leveraged with CMIP6 General Circulation Models

Climate change is escalating the frequency and intensity of extreme precipitation events, significantly influencing the spatial and temporal distributions of water resources. This is particularly evident in Texas, a rapidly growing state with a pronounced west-east gradient in water supply. This study utilizes Coupled Model Intercomparison Project Phase 6 (CMIP6) data and data-driven methodology to improve projections of Texas\u27s future water resources, focusing on actual evapotranspiration (AET) and water availability through enhanced Multi-Model Ensembles. The results reveal that the data-driven model significantly outperforms the CMIP5 and CMIP6 models across all skill metrics, underscoring the potential of data-driven methodologies in advancing climate science. Furthermore, the study provides an in-depth analysis of the projected changes in net water availability (NWA) and estimated water demand for different regions in Texas over the next six decades from 2015 to 2074, which reveal fluctuating patterns of water stress, with the regions (nine out of sixteen water planning regions in Texas, especially for the most populated regions) poised for heightened challenges in reconciling water demand and availability. While increasing trends are found in precipitation, AET, and NWA for the northern region of Texas based on SSP2–4.5, decreasing trends are found over the southern region for all three parameters based on SSP5–8.5. These findings underscore the importance of factoring both spatial and temporal variations in water availability and demand for effective water management strategies and the need for adaptive water management strategies for the changing water availability scenarios