496 research outputs found
A New SLNR-based Linear Precoding for Downlink Multi-User Multi-Stream MIMO Systems
Signal-to-leakage-and-noise ratio (SLNR) is a promising criterion for linear
precoder design in multi-user (MU) multiple-input multiple-output (MIMO)
systems. It decouples the precoder design problem and makes closed-form
solution available. In this letter, we present a new linear precoding scheme by
slightly relaxing the SLNR maximization for MU-MIMO systems with multiple data
streams per user. The precoding matrices are obtained by a general form of
simultaneous diagonalization of two Hermitian matrices. The new scheme reduces
the gap between the per-stream effective channel gains, an inherent limitation
in the original SLNR precoding scheme. Simulation results demonstrate that the
proposed precoding achieves considerable gains in error performance over the
original one for multi-stream transmission while maintaining almost the same
achievable sum-rate.Comment: 8 pages, 1 figur
A novel traveling-wave-based method improved by unsupervised learning for fault location of power cables via sheath current monitoring
In order to improve the practice in maintenance of power cables, this paper proposes a novel traveling-wave-based fault location method improved by unsupervised learning. The improvement mainly lies in the identification of the arrival time of the traveling wave. The proposed approach consists of four steps: (1) The traveling wave associated with the sheath currents of the cables are grouped in a matrix; (2) the use of dimensionality reduction by t-SNE (t-distributed Stochastic Neighbor Embedding) to reconstruct the matrix features in a low dimension; (3) application of the DBSCAN (density-based spatial clustering of applications with noise) clustering to cluster the sample points by the closeness of the sample distribution; (4) the arrival time of the traveling wave can be identified by searching for the maximum slope point of the non-noise cluster with the fewest samples. Simulations and calculations have been carried out for both HV (high voltage) and MV (medium voltage) cables. Results indicate that the arrival time of the traveling wave can be identified for both HV cables and MV cables with/without noise, and the method is suitable with few random time errors of the recorded data. A lab-based experiment was carried out to validate the proposed method and helped to prove the effectiveness of the clustering and the fault location
T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity.
BACKGROUND: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examined whether T-cad deficiency increases vascular vulnerability in T2DM.
METHODS: Vascular segments were isolated from WT or T-cad knockout mice. Endothelial function, total NO accumulation, and the expression of T-cad related proteins were determined.
RESULTS: Ach and acidified NaNO2 induced similar vasorelaxation in WT groups. T-cad KO mice exhibited normal response to acidified NaNO2, but manifested markedly reduced response to Ach. NO accumulation was also decreased in T-cad KO group. T-cad expression was reduced in WT mice fed 8 weeks of high fat diet (HFD). Furthermore, exacerbated reduction of vasorelaxation was observed in T-cad KO mice fed 8 weeks of HFD.
CONCLUSIONS: In the current study, we provide the first in vivo evidence that T-cadherin deficiency causes endothelial dysfunction in T2DM vascular segments, suggesting the involvement of T-cad deficiency in T2DM pathogenesis
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