Prostate lymphoscintigraphy and radio-guided surgery for sentinel lymph node identification in prostate cancer - Technique and results of the first 350 cases

Introduction: Having in mind the promising results of lymphoscintigraphy and intraoperative gamma probe application for the detection of sentinel lymph nodes (SLN) in malignant melanoma, breast and penis cancer, we tried to identify the SLN in prostate cancer by applying a comparable technique. Materials and Method. 350 patients with prostate cancer were examined after providing informed consent. The day before pelvic lymphadenectomy technetium-99m nanocolloid was transrectally injected into the prostate under ultrasound guidance. A single central application was done per prostate lobe in most cases. Activity attained 90400 MBq, and the total injected volume was about 2-3 ml. Hereafter, lymphoscintigraphy was carried out. Those lymph nodes having been identified as SLN by means of gamma probe detection and lymphoscintigraphy were removed intraoperatively. Later, most of the cases had different types of pelvic lymphadenectomy. SLN received serial sections and immunohistochemistry, non-SLN step sections. Results: 335 patients showed at least 1 SLN in lymphoscintigraphy. 24.7% had lymph node metastases. In 2 patients, metastases in non-SLN were found without at least one SLN being affected (false-negative patient). Conclusion:Our experience suggests that the SLN identification is not only feasible in breast cancer and malignant melanoma, but also in prostate cancer with a comparable technique. Copyright (C) 2003 S. Karger AG, Basel

Ion beam assisted deposition induced composition changes in titanium nitride

Ion beam assisted deposition induced composition changes in titanium nitride / H. Wengenmair ... - In: Physica status solidi. A. 155. 1996. S. 181-18

Influence of additional UV-light illumination on preparation of TiN by ion beam assisted deposition

Influence of additional UV-light illumination on preparation of TiN by ion beam assisted deposition / H. Wengenmair ... - In: Nuclear instruments and methods in physics research. B. 120. 1996. S. 286-28

Biaxial alignment of TiN films prepared by ion beam assisted deposition

Biaxial alignment of TiN films prepared by ion beam assisted deposition / H. Wengenmair ... - In: Applied physics letters. 68. 1996. S. 2360-236

Mechanical characterisation of titanium nitride films formed by low-energy ion beam assisted deposition

Mechanical characterisation of titanium nitride films formed by low-energy ion beam assisted deposition / H. Wengenmair ... - In: Surface and coatings technology. 84. 1996. S. 439-44

Titanium nitride formation by low energy Ar ion bombardment and UV-light irradiation during deposition

AbstractTitanium nitride films were produced by a newly developed photon and ion beam assisted deposition system (PHIBAD system). With an electron beam evaporator titanium was deposited on silicon substrates in a controlled nitrogen environment. The growing δ-TiN films were bombarded with argon ions and illuminated with UV-light. The results demonstrate that the impurity content, the nitrogen to titanium ratio of the films, the microstructure and the crystal alignment are changed using UV-light irradiation during ion assisted deposition.</jats:p