4,096 research outputs found
BIOMECHANICAL ANALYSIS OF THE GRAB AND TRACK SWIMMING STARTS
The aim of this study was to compare the grab and track competitive swimming starts. Twelve male college competitive swimmers (six used the grab start and six the track start) participated in this study. Data were collected from two video cameras (60Hz) above water. The video data were digitized and analysis was performed with the Kwon3D Motion Analysis system. No significant differences existed between the two groups for flight time and distance, time to 12m, takeoff velocity and angle, entry velocity and angle and the center of mass at highest position above water. The track start had the centre of mass on the block more towards the rear and a shorter block time (
Effects of Magnetic Fields on the Diskoseismic Modes of Accreting Black Holes
The origin of the rapid quasi-periodic variabilities observed in a number of
accreting black hole X-ray binaries is not understood. It has been suggested
that these variabilities are associated with diskoseismic oscillation modes of
the black hole accretion disk. In particular, in a disk with no magnetic field,
the so-called g-modes (inertial oscillations) can be self-trapped at the inner
region of the disk due to general relativistic effects. Real accretion disks,
however, are expected to be turbulent and contain appreciable magnetic fields.
We show in this paper that even a weak magnetic field (with the magnetic energy
much less than the thermal energy) can modify or "destroy" the self-trapping
zone of disk g-modes, rendering their existence questionable in realistic black
hole accretion disks. The so-called corrugation modes (c-modes) are also
strongly affected when the poloidal field approaches equal-partition. On the
other hand, acoustic oscillations (p-modes), which do not have vertical
structure, are not affected qualitatively by the magnetic field, and therefore
may survive in a turbulent, magnetic disk.Comment: 21 pages, 5 figures, accepted for publication in Ap
Molecular evolution of measles viruses circulated in Taiwan 1992-2008
Genetic analyses of viral samples from 74 laboratory confirmed measles cases occurring in Taiwan during 1992-2008 identified six viral genotypes D3, D5, D9, G2, H1 and H2. The most frequently detected genotype, H1, was associated with outbreaks in 1994 and 2002, and was the likely indigenous genotype in 1992. In response to the outbreaks, two catch-up campaigns were launched and a routine second dose of measles, mumps, and rubella vaccine at entry to elementary school was introduced. The vaccination campaigns successfully reduced the number of measles cases in Taiwan, and many of the more recent cases can be traced to importations, primarily from other Asian countries. A number of measles genotypes which were associated with outbreaks in other Asian countries were detected among the more recent cases. The more recent genotype H1 viruses had sequences that were identical to those currently circulating in China or associated with international importation of virus
Charge-Trapping Devices Using Multilayered Dielectrics for Nonvolatile Memory Applications
Charge-trapping devices using multilayered dielectrics were studied for nonvolatile memory applications. The device structure is Al/Y2O3/Ta2O5/SiO2/Si (MYTOS). The MYTOS field effect transistors were fabricated using Ta2O5 as the charge storage layer and Y2O3 as the blocking layer. The electrical characteristics of memory window, program/erase characteristics, and data retention were examined. The memory window is about 1.6 V. Using a pulse voltage of 6 V, a threshold voltage shift of ~1 V can be achieved within 10 ns. The MYTOS transistors can retain a memory window of 0.81 V for 10 years
Incompressible Quantum Liquids and New Conservation Laws
In this letter we investigate a class of Hamiltonians which, in addition to
the usual center-of-mass (CM) momentum conservation, also have center-of-mass
position conservation. We find that regardless of the particle statistics, the
energy spectrum is at least q-fold degenerate when the filling factor is ,
where and are coprime integers. Interestingly the simplest Hamiltonian
respecting this type of symmetry encapsulates two prominent examples of novel
states of matter, namely the fractional quantum Hall liquid and the quantum
dimer liquid. We discuss the relevance of this class of Hamiltonian to the
search for featureless Mott insulators.Comment: updated version, to be published by PR
Evaluation of Lentiviral-Mediated Expression of Sodium Iodide Symporter in Anaplastic Thyroid Cancer and the Efficacy of In Vivo Imaging and Therapy
Anaplastic thyroid carcinoma (ATC) is one of the most deadly cancers. With intensive multimodalities of treatment, the survival remains low. ATC is not sensitive to 131I therapy due to loss of sodium iodide symporter (NIS) gene expression. We have previously generated a stable human NIS-expressing ATC cell line, ARO, and the ability of iodide accumulation was restored. To make NIS-mediated gene therapy more applicable, this study aimed to establish a lentiviral system for transferring hNIS gene to cells and to evaluate the efficacy of in vitro and in vivo radioiodide accumulation for imaging and therapy. Lentivirus containing hNIS cDNA were produced to transduce ARO cells which do not concentrate iodide. Gene expression, cell function, radioiodide imaging and treatment were evaluated in vitro and in vivo. Results showed that the transduced cells were restored to express hNIS and accumulated higher amount of radioiodide than parental cells. Therapeutic dose of 131I effectively inhibited the tumor growth derived from transduced cells as compared to saline-treated mice. Our results suggest that the lentiviral system efficiently transferred and expressed hNIS gene in ATC cells. The transduced cells showed a promising result of tumor imaging and therapy
Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes
<p>Abstract</p> <p>Background</p> <p>Meta-analysis has demonstrated an exponential relationship between 2-hr postchallenge hyperglycemia and coronary artery disease (CAD). Pulsatile hyperglycemia can acutely increase proinflammatory cytokines by oxidative stress. We hypothesized that postchallenge proinflammatory and nitrosative responses after 75 g oral glucose tolerance tests (75 g-OGTT) might be associated with CAD in patients without previously recognized type 2 diabetes mellitus (T2DM).</p> <p>Methods</p> <p>Serial changes of plasma glucose (PG), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and nitrotyrosine levels were analyzed during 75 g-OGTT in 120 patients (81 male; age 62 ± 11 years) before coronary angiography. Patients were classified as normal (NGT; 42%), impaired (IGT; 34%) and diabetic (T2DM; 24%) glucose tolerance by 75 g-OGTT.</p> <p>Results</p> <p>Postchallenge hyperglycemia elicited TNF-α, IL-6 and nitrotyrosine levels time-dependently, and 2-hr median levels of TNF-α (7.1 versus 6.4 pg/ml; <it>P </it>< 0.05) and nitrotyrosine (1.01 versus 0.83 <it>μ</it>mol/l; <it>P </it>< 0.05), but not IL-6 or PG, were significantly higher in patients with CAD in either IGT or T2DM groups. After adjusting risk factors and glucose tolerance status, 2-hr nitrotyrosine in highest quartiles (OR: 3.1, <it>P </it>< 0.05) remained an independent predictor of CAD by logistic regression analysis.</p> <p>Conclusions</p> <p>These results highlight postchallenge proinflammatory and nitrosative responses by 75 g-OGTT, rather than hyperglycemia <it>per se</it>, are associated with CAD in patients without previous recognized diabetes.</p
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