Unusual presentation of cutaneous metastatic malignant melanoma

This report describes an unusual presentation of cutaneous metastases suspected to have occurred through lymphatic spread in a patient with malignant melanoma. Punctate papular skin lesions correlated histologically with small tumor foci in the papillary dermis

Procainamide-induced urticarial vasculitis

Common urticaria may be caused by a multitude of medications. If the lesions are persistent and the histology shows a vasculitic pattern of inflammation, this may not be common hives, but rather, urticarial vasculitis. We report the first two cases of procainamide-induced urticarial vasculitis and suggest that recognition of this clinical syndrome may be helpful to clinicians in deciding which drug to discontinue when faced with a patient with an urticarial cutaneous reaction who is receiving multiple medications. In addition, recognition of this syndrome should prompt further evaluation of these patients for features of systemic lupus erythematosus

Superficial granulomatous pyoderma

Superficial granulomatous pyoderma, recently described as a variant of pyoderma gangrenosum, would be better termed pathergic granulomatous cutaneous ulceration as the seven previously described cases, as well as our own two cases, have significant dermal involvement histologically and heal with scarring. In contrast to pyoderma gangrenosum, lesions of superficial granulomatous pyoderma respond to less toxic anti-inflammatory agents

LICHENOID DRUG ERUPTION SECONDARY TO PROPRANOLOL

Propranolol, a widely prescribed beta-adrenergic receptor blocker, has occasionally been associated with adverse cutaneous reactions. We present a case of ulcerative lichenoid drug eruption of the penis secondary to propranolol therapy. This unusual clinical presentation has not been described previously in the literature

Autoimmune hemolytic anemia in a patient with mycosis fungoides

We report a case of autoimmune hemolytic anemia in a patient with mycosis fungoides. We propose that autoimmune hemolytic anemia may be induced by cutaneous lymphoproliferative diseases. Thus, hemolysis should be considered as a mechanism of anemia in patients with mycosis fungoides