10,704 research outputs found

    Computation of the Halo Mass Function Using Physical Collapse Parameters: Application to Non-Standard Cosmologies

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    In this article we compare the halo mass function predicted by the excursion set theory with a drifting diffusive barrier against the results of N-body simulations for several cosmological models. This includes the standard LCDM case for a large range of halo masses, models with different types of primordial non-Gaussianity, and the Ratra-Peebles quintessence model of Dark Energy. We show that in all those cosmological scenarios, the abundance of dark matter halos can be described by a drifting diffusive barrier, where the two parameters describing the barrier have physical content. In the case of the Gaussian LCDM, the statistics are precise enough to actually predict those parameters at different redshifts from the initial conditions. Furthermore, we found that the stochasticity in the barrier is nonnegligible making the simple deterministic spherical collapse model a bad approximation even at very high halo masses. We also show that using the standard excursion set approach with a barrier inspired by peak patches leads to inconsistent predictions of the halo mass function.Comment: 25 pages, 12 figure

    Best practice report – operation and maintenance requirements

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    Deliverable 3.6.3 from the MERiFIC Project A report prepared as part of the MERiFIC Project "Marine Energy in Far Peripheral and Island Communities"This report is a deliverable of MERiFIC Work Package 3.6: ‘Operation and Maintenance requirements’ and has been produced as a cross border collaboration between IFREMER and the University of Exeter. The report provides an overview of guidelines and recommendations for the management of O&M operations necessary for an optimal exploitation of Marine energy plants, with a focus on the specific areas of South West Cornwall, UK and Iroise sea, Brittany, France. An overview of the onshore infrastructures and ports possibly suitable for management of such O&M operations is also provided. Management of scheduled and unscheduled maintenance operations are discussed in their various aspects including site accessibility. It should be noted that this topic, including weather window assessment for operations is discussed in more details in the additional MERIFIC report D3.6.2: Best Practice for installation proceduresMERiFIC was selected under the European Cross-Border Cooperation Programme INTERREG IV A France (Channel) – England, co-funded by the ERDF

    New insights into acquired temozolomide resistance in glioblastoma?

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    “I wish I’d told them”: a qualitative study examining the unmet psychosexual needs of prostate cancer patients during follow-up after treatment

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    <b>Objective</b> To gain insight into patients' experiences of follow-up care after treatment for prostate cancer and identify unmet psychosexual needs.<p></p> <b>Methods</b> Semi-structured interviews were conducted with a purposive sample of 35 patients aged 59-82 from three UK regions. Partners were included in 18 interviews. Data were analyzed using constant comparison. <p></p> <b>Results</b> (1) Psychosexual problems gained importance over time, (2) men felt they were rarely invited to discuss psychosexual side effects within follow-up appointments and lack of rapport with health care professionals made it difficult to raise problems themselves, (3) problems were sometimes concealed or accepted and professionals' attempts to explore potential difficulties were resisted by some, and (4) older patients were too embarrassed to raise psychosexual concerns as they felt they would be considered 'too old' to be worried about the loss of sexual function.<p></p> <b>Conclusion</b> Men with prostate cancer, even the very elderly, have psychosexual issues for variable times after diagnosis. These are not currently always addressed at the appropriate time for the patient.Practice implications Assessments of psychosexual problems should take place throughout the follow-up period, and not only at the time of initial treatment. Further research examining greater willingness or reluctance to engage with psychosexual interventions may be particularly helpful in designing future intervention

    The role of practice in doctoral degrees. Research in Post-Compulsory Education, 26:3, 257-273, ISSN 1359-6748

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    The role of practice in doctoral degrees connects with how `knowledge’ itself is understood and involves a wider category of knowledge creation inclusive of considerations of practice and also offers more than the application of theoretical knowledge. Concepts of knowledge and what is counted as worthwhile knowledge increasingly incorporate a trandsiciplinary approach, which is more inclusive of professional and artistic knowledge and more practice-based. Often, the aim is to achieve practice-based outcomes that make positive changes to practice. This is the case both for PhDs that have a focus on practice and for professional doctorates. A transdisciplinary lens on the world can open our eyes to multiple realities, and in this sense, academic disciplines that break down knowledge into discrete and bounded areas of knowledge are necessary, but are not always sufficient to support real world developments

    Technical innovation changes standard radiographic protocols in veterinary medicine: is it necessary to obtain two dorsoproximal-palmarodistal oblique views of the equine foot when using computerised radiography systems?

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    Since the 1950s, veterinary practitioners have included two separate dorsoproximal–palmarodistal oblique (DPr–PaDiO) radiographs as part of a standard series of the equine foot. One image is obtained to visualise the distal phalanx and the other to visualise the navicular bone. However, rapid development of computed radiography and digital radiography and their post-processing capabilities could mean that this practice is no longer required. The aim of this study was to determine differences in perceived image quality between DPr–PaDiO radiographs that were acquired with a computerised radiography system with exposures, centring and collimation recommended for the navicular bone versus images acquired for the distal phalanx but were subsequently manipulated post-acquisition to highlight the navicular bone. Thirty images were presented to four clinicians for quality assessment and graded using a 1–3 scale (1=textbook quality, 2=diagnostic quality, 3=non-diagnostic image). No significant difference in diagnostic quality was found between the original navicular bone images and the manipulated distal phalanx images. This finding suggests that a single DPr–PaDiO image of the distal phalanx is sufficient for an equine foot radiographic series, with appropriate post-processing and manipulation. This change in protocol will result in reduced radiographic study time and decreased patient/personnel radiation exposure

    Meteorological factors in Earth-satellite propagation

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    Using the COMSTAR D/4 28.56 GHz beacon as a source, a differential gain experiment was performed by connecting a 5-meter paraboloidal antenna and a 0.6-meter paraboloidal antenna alternately to the same receiver. Substantial differential gain changes were observed during some, but not all, rain events. A site-diversity experiment was implemented which consists of two 28.56 GHz radiometers separated by 9 km. The look-angle corresponds to that of the D/4 beacon, and data were obtained with one radiometer during several weeks of concurrent beacon operation to verify the system calibration. A theoretical study of the effect of scattering from a nonuniform rain distribution along the path is under way to aid in interpreting the results of this experiment. An improved empirical site diversity-gain model was derived from data in the literature relating to 34 diversity experiments. Work on the experiment control and data acquisition system is continuing with a view toward future experiments

    Undersampled Phase Retrieval with Outliers

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    We propose a general framework for reconstructing transform-sparse images from undersampled (squared)-magnitude data corrupted with outliers. This framework is implemented using a multi-layered approach, combining multiple initializations (to address the nonconvexity of the phase retrieval problem), repeated minimization of a convex majorizer (surrogate for a nonconvex objective function), and iterative optimization using the alternating directions method of multipliers. Exploiting the generality of this framework, we investigate using a Laplace measurement noise model better adapted to outliers present in the data than the conventional Gaussian noise model. Using simulations, we explore the sensitivity of the method to both the regularization and penalty parameters. We include 1D Monte Carlo and 2D image reconstruction comparisons with alternative phase retrieval algorithms. The results suggest the proposed method, with the Laplace noise model, both increases the likelihood of correct support recovery and reduces the mean squared error from measurements containing outliers. We also describe exciting extensions made possible by the generality of the proposed framework, including regularization using analysis-form sparsity priors that are incompatible with many existing approaches.Comment: 11 pages, 9 figure
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