1,081 research outputs found
Novel Nonreciprocal Acoustic Effects in Antiferromagnets
The possible occurrence of nonreciprocal acoustic effects in antiferromagnets
in the absence of an external magnetic field is investigated using both (i) a
microscopic formulation of the magnetoelastic interaction between spins and
phonons and (ii) symmetry arguments. We predict for certain antiferromagnets
the existence of two new nonreciprocal (non-time invariant) effects:
A boundary-condition induced nonreciprocal effect and the occurrence of
transversal phonon modes propagating in opposite directions having different
velocities. Estimates are given and possible materials for these effects to be
observed are suggested.Comment: Euro. Phys. Lett. (in press
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Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels.
BRCA1/2 mutations are significant risk factors for hereditary breast and ovarian cancer (HBOC), its mutation frequency in HBOC of Chinese ethnicity is around 9%, in which nearly half are recurrent mutations. In Hong Kong and China, genetic testing and counseling are not as common as in the West. To reduce the barrier of testing, a multiplex SNaPshot genotyping panel that targeted 25 Chinese BRCA1/2 mutation hotspots was developed, and its feasibility was evaluated in a local cohort of 441 breast and 155 ovarian cancer patients. For those who tested negative, they were then subjected to full-gene testing with next-generation sequencing (NGS). BRCA mutation prevalence in this cohort was 8.05% and the yield of the recurrent panel was 3.52%, identifying over 40% of the mutation carriers. Moreover, from 79 Chinese breast cancer cases recruited overseas, 2 recurrent mutations and one novel BRCA2 mutation were detected by the panel and NGS respectively. The developed genotyping panel showed to be an easy-to-perform and more affordable testing tool that can provide important contributions to improve the healthcare of Chinese women with cancer as well as family members that harbor high risk mutations for HBOC
FACT - Threshold prediction for higher duty cycle and improved scheduling
The First G-APD Cherenkov telescope (FACT) is the first telescope using
silicon photon detectors (G-APD aka. SiPM). The use of Silicon devices promise
a higher photon detection efficiency, more robustness and higher precision than
photo-multiplier tubes. Being operated during different light-conditions, the
threshold settings of a Cherenkov telescope have to be adapted to feature the
lowest possible threshold but also an efficient suppression of triggers from
night-sky background photons. Usually this threshold is set either by
experience or a mini-ratescan. Since the measured current through the sensors
is directly correlated with the noise level, the current can be used to set the
best threshold at any time. Due to the correlation between the physical
threshold and the final energy threshold, the current can also be used as a
measure for the energy threshold of any observation. This presentation
introduces a method which uses the properties of the moon and the source
position to predict the currents and the corresponding energy threshold for
every upcoming observation allowing to adapt the observation schedule
accordingly
FACT - Long-term Monitoring of Bright TeV-Blazars
Since October 2011, the First G-APD Cherenkov Telescope (FACT) is operated
successfully on the Canary Island of La Palma. Apart from the proof of
principle for the use of G-APDs in Cherenkov telescopes, the major goal of the
project is the dedicated long-term monitoring of a small sample of bright TeV
blazars. The unique properties of G-APDs permit stable observations also during
strong moon light. Thus a superior sampling density is provided on time scales
at which the blazar variability amplitudes are expected to be largest, as
exemplified by the spectacular variations of Mrk 501 observed in June 2012.
While still in commissioning, FACT monitored bright blazars like Mrk 421 and
Mrk 501 during the past 1.5 years so far. Preliminary results including the Mrk
501 flare from June 2012 will be presented.Comment: 4 pages, 4 figures, presented at the 33rd ICRC (2013
FACT - How stable are the silicon photon detectors?
The First G-APD Cherenkov telescope (FACT) is the first telescope using
silicon photon detectors (G-APD aka. SiPM). The use of Silicon devices promise
a higher photon detection efficiency, more robustness and higher precision than
photo-multiplier tubes. Since the properties of G-APDs depend on auxiliary
parameters like temperature, a feedback system adapting the applied voltage
accordingly is mandatory.
In this presentation, the feedback system, developed and in operation for
FACT, is presented. Using the extraction of a single photon-equivalent (pe)
spectrum as a reference, it can be proven that the sensors can be operated with
very high precision. The extraction of the single-pe, its spectrum up to
10\,pe, its properties and their precision, as well as their long-term behavior
during operation are discussed. As a by product a single pulse template is
obtained. It is shown that with the presented method, an additional external
calibration device can be omitted. The presented method is essential for the
application of G-APDs in future projects in Cherenkov astronomy and is supposed
to result in a more stable and precise operation than possible with
photo-multiplier tubes
FACT - Long-term stability and observations during strong Moon light
The First G-APD Cherenkov Telescope (FACT) is the first Cherenkov telescope
equipped with a camera made of silicon photon detectors (G-APD aka. SiPM).
Since October 2011, it is regularly taking data on the Canary Island of La
Palma. G-APDs are ideal detectors for Cherenkov telescopes as they are robust
and stable. Furthermore, the insensitivity of G-APDs towards strong ambient
light allows to conduct observations during bright Moon and twilight. This gain
in observation time is essential for the long-term monitoring of bright TeV
blazars. During the commissioning phase, hundreds of hours of data (including
data from the the Crab Nebula) were taken in order to understand the
performance and sensitivity of the instrument. The data cover a wide range of
observation conditions including different weather conditions, different zenith
angles and different light conditions (ranging from dark night to direct full
Moon). We use a new parmetrisation of the Moon light background to enhance our
scheduling and to monitor the atmosphere. With the data from 1.5 years, the
long-term stability and the performance of the camera during Moon light is
studied and compared to that achieved with photomultiplier tubes so far.Comment: 3 pages, 3 figures, FACT Contribution to the 33rd International
Cosmic Ray Conference (ICRC), Rio de Janeir
Specific heat amplitude ratios for anisotropic Lifshitz critical behaviors
We determine the specific heat amplitude ratio near a -axial Lifshitz
point and show its universal character. Using a recent renormalization group
picture along with new field-theoretical -expansion techniques,
we established this amplitude ratio at one-loop order. We estimate the
numerical value of this amplitude ratio for and . The result is in
very good agreement with its experimental measurement on the magnetic material
. It is shown that in the limit it trivially reduces to the
Ising-like amplitude ratio.Comment: 8 pages, RevTex, accepted as a Brief Report in Physical Review
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