8 research outputs found
Differential vasorelaxant effects of KR-30075, a new cyclic AMP-phosphodiesterase inhibitor, on guinea-pig pulmonary, bovine coronary and renal arteries
Calcium and Vitamin D Supplementation. Myths and Realities with Regard to Cardiovascular Risk
New insights on low vitamin D plasma concentration as a potential cardiovascular risk factor
The role of Vitamin D hormone in human health and disease is still debated. Recently, growing attention has been paid to its putative role in cardiovascular system homeostasis with several studies that suggested a correlation between low vitamin D levels and increased cardiovascular risk. Several mechanisms are involved in the development of cardiovascular diseases: systemic inflammation, endothelial dysfunction, arterial hypertension and insulin resistance. In the present paper, we have revised the current literature supporting a role for vitamin D in the development of these pathogenetic processes. Finally, we have evaluated the current evidence linking vitamin D to atherosclerosis and its natural consequence, cardiovascular diseases