Partial pressure of end-tidal carbon dioxide predicts successful cardiopulmonary resuscitation in the field

Kolar and colleagues contribute an additional and important incentive for rescuers to utilize end-tidal carbon dioxide tensions as a routine monitor to guide management and decision-making during cardiopulmonary resuscitation. They conclude that below-threshold levels of 14 mmHg (1.5 kPa) measured after 20 minutes of cardiopulmonary resuscitation reliably predict that spontaneous circulation cannot be restored

Чернобыль и Фукусима. Анализ крупнейших радиационных аварий

Около 8000 километров и четверть века разделяют катастрофы на АЭС в Чернобыле и Фукусиме. В данной статье проведена сравнительная оценка показателей ущерба, допустимые содержания радиоактивных веществ в продуктах питания от Чернобыльской аварии и аварии «Фукусима-1».About 8000 kilometers and a quarter of a century are divided by the catastrophe at the nuclear power plants in Chernobyl and Fukushima. In this article, a comparative assessment of the damage indicators, the permissible content of radioactive substances in food products from the Chernobyl accident and the accident of "Fukushima-1.

Alpha-methylnorepinephrine, a selective alpha2-adrenergic agonist for cardiac resuscitation

AbstractOBJECTIVESThe purpose of this study was to investigate the effects of a selective alpha2-adrenergic agonist, alpha-methylnorepinephrine (alphaMNE) as an alternative vasopressor agent during cardiopulmonary resuscitation (CPR).BACKGROUNDFor more than 40 years, epinephrine has been the vasopressor agent of choice for CPR. Its beta- and alpha1-adrenergic effects increase myocardial oxygen consumption, magnify global myocardial ischemia and increase the severity of postresuscitation myocardial dysfunction.METHODSVentricular fibrillation (VF) was induced in 20 Sprague-Dawley rats. After 8 min of untreated VF, mechanical ventilation and precordial compression began. AlphaMNE, epinephrine or saline placebo was injected into the right atrium 2 min after the start of precordial compression. As an additional control, one group of animals was pretreated with alpha2-receptor blocker, yohimbine, before injection of alphaMNE. Defibrillation was attempted 4 min later. Left ventricular pressure, dP/dt40, negative dP/dt and cardiac index were measured for an interval of 240 min after resuscitation.RESULTSExcept for saline placebo and yohimbine-treated animals, comparable increases in coronary perfusion pressure were observed after each drug intervention. All animals were successfully resuscitated. Left ventricular diastolic pressure, cardiac index, dP/dt40and negative dP/dt were more optimal after alphaMNE; this was associated with significantly better postresuscitation survival. Pretreatment with yohimbine abolished the beneficial effects of alphaMNE.CONCLUSIONSThe selective alpha2-adrenergic agonist, alphaMNE, was as effective as epinephrine for initial cardiac resuscitation but provided strikingly better postresuscitation myocardial function and survival

Содержание тяжелых металлов в почвах селитебной территории АО "АП Саратовский завод резервуарных металлоконструкций"

В октябре 2017 года исследованы почвы на территории г.Саратова в Ленинском районе. Определение валового содержания ТМ в почве проводилось на рентгенофлуоресцентном спектрометре “Spectroskan МАX - G”. Установлено, что уровень загрязнения исследуемых почв относится к допустимой категории, однако есть образцы, в которых превышение ПДК по свинцу более чем в 5 раз, а по цинку в 3.5 раза.The soil survey was conducted in October 2017 on the territory of Saratov in the Leninsky district. The determination of gross TM content in soil was carried out on the X-ray fluorescence spectrometer "Spectroskan MAX - G". Established that the level of contamination of soils refers to a valid category, but there are specimens in which excessive concentrations of lead more than 5 times, and zinc by 3.5 times