Control Strategy of Photovoltaic DC Microgrid Based on Fuzzy EEMD

In order to improve the accuracy of power time series regulation of DC microgrid photovoltaic power generation and its hybrid energy storage system, a set of empirical mode decomposition (EEMD) control strategy based on fuzzy algorithm optimization is proposed in this paper. Through EEMD decomposition of photovoltaic power data, a set of eigenmode component functions is obtained, the EEMD power decomposition method is designed, and the EEMD optimization fuzzy control strategy is established. Finally, the effectiveness and accuracy of the controller are verified by simulation experiments. The results show that compared with the ordinary EEMD power decomposition control method, the proposed method can achieve better control effect under different power fluctuation characteristics, improve the strong randomness and fluctuation of distributed generation fluctuation, and has strong applicability

Transmission of sodium chloride in PDMS membrane during Pervaporation based on polymer relaxation

Polydimethylsiloxane (PDMS) composite membrane is used for treating pharmaceutical wastewater containing NaCl and solvent. In this study, the influence of feed concentrations of NaCl and isobutanol, process temperature and membrane microstructures on salt rejection are evaluated. Microstructures of PDMS membrane before and after separation are characterized by nuclear magnetic resonance (NMR), energy dispersive X-ray spectroscopy (EDS), scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and Positron annihilation life-time spectroscopy (PALS). The PV results show that NaCl will not spontaneously enter PDMS membrane without isobutanol. However, while NaCl feed concentration is 13 wt%, salt rejection of PDMS membrane drops from 100% to 99.09% with increasing feed concentration of isobutanol (up to 7 wt%). On the contrary, a higher temperature increases salt rejection of PDMS membrane and NaCl permeation through PDMS membrane is not through a vapor permeate process. Due to the relaxation of PDMS polymer chain, when PDMS cross-linking ratio is 0.1, the salt rejection increases from 99.87% to 100% with its thickness increasing from 10 ?m to 17.5 ?m. While the cross-linking ratio rises to 0.2, the salt rejection is 100% with the PDMS layer thickness of 10 ?m. The relationship between relaxation of polymer chains and transport of NaCl in PDMS membrane is an excellent guidance and will be beneficial for the treatment of saline organic wastewater

Periostin: a promising target of therapeutical intervention for prostate cancer

<p>Abstract</p> <p>Background</p> <p>In our recent study, Periostin was up-regulated in prostate cancer(PCa) compared with benign prostate hyperplasia (BPH) by proteomics analysis of prostate biopsies. We investigated the effect of sliencing Periostin by RNA interference (RNAi) on the proliferation and migration of PCa LNCap cell line.</p> <p>Methods</p> <p>All the prostate biopsies from PCa, BPH and BPH with local prostatic intraepithelial neoplasm(PIN) were analyzed by iTRAQ(Isobaric tags for relative and absolute quantification) technology. Western blotting and immunohistochemical staining were used to verify Periostin expression in the tissues of PCa. Periostin expression in different PCa cell lines was determined by immunofluorescence staining, western blotting and reverse transcription PCR(RT-PCR). The LNCap cells with Periostin expression were used for transfecting shRNA-Periostin lentiviral particles. The efficancy of transfecting shRNA lentiviral particles was evaluated by immunofluorescence, western blotting and Real-time PCR. The effect of silencing Periostin expression by RNAi on proliferation of LNCap cells was determined by MTT assay and tumor xenografts. The tissue slices from theses xenografts were analyzed by hematoxylin and eosin(HE) staining. The expression of Periostin in the xenografts was deteminned by Immunohistochemical staining and western blotting. The migration of LNCap cells after silencing Periostin gene expression were analyzed in vitro.</p> <p>Results</p> <p>Periostin as the protein of interest was shown 9.12 fold up-regulation in PCa compared with BPH. The overexpression of Periostin in the stroma of PCa was confirmed by western blotting and immunohistochemical staining. Periostin was only expressed in PCa LNCap cell line. Our results indicated that the transfection ratio was more than 90%. As was expected, both the protein level and mRNA level of Periostin in the stably expressing shRNA-Periostin LNCap cells were significantly reduced. The stably expressing shRNA-Periostin LNCap cells growed slowly in vitro and in vivo. The tissues of xenografts as PCa were verificated by HE staining. Additionally, the weak positive Periostin expressed tumor cells could be seen in the tissues of 6 xenografts from the group of down-regulated Periostin LNCap cells which had a significant decrease of the amount of Periostin compared to the other two group. Furthermore, our results demonstrated that sliencing Periostin could inhibit migration of LNCap cells in vitro.</p> <p>Conclusions</p> <p>Our data indicates that Periostin as an up-regulated protein in PCa may be a promising target of therapeutical intervention for PCa in future.</p

Dynamic Navigation Method with Multisubstations Based on Doppler Shift

The mobile terminals must be compensated for the Doppler effect in their moving communication. This special characteristic of mobile communication can be developed in some new applications. This paper proposes methods to realize mobile navigation calculation via Doppler shifts. It gives the theory of relationship between the motion parameters, like directions and speed, and frequency shifts caused by multibase stations. The simulation illustrates how to compute the movement parameters of numerical calculation and what should be care for the problem near angle 90 degree. It also gives an application with Google map and dynamical locating position and direction on a mobile phone by public wireless network. Given the simulation analysis and navigation test, the results show that this method has a good effect

Learning Two-Stream CNN for Multi-Modal Age-related Macular Degeneration Categorization

This paper tackles automated categorization of Age-related Macular Degeneration (AMD), a common macular disease among people over 50. Previous research efforts mainly focus on AMD categorization with a single-modal input, let it be a color fundus image or an OCT image. By contrast, we consider AMD categorization given a multi-modal input, a direction that is clinically meaningful yet mostly unexplored. Contrary to the prior art that takes a traditional approach of feature extraction plus classifier training that cannot be jointly optimized, we opt for end-to-end multi-modal Convolutional Neural Networks (MM-CNN). Our MM-CNN is instantiated by a two-stream CNN, with spatially-invariant fusion to combine information from the fundus and OCT streams. In order to visually interpret the contribution of the individual modalities to the final prediction, we extend the class activation mapping (CAM) technique to the multi-modal scenario. For effective training of MM-CNN, we develop two data augmentation methods. One is GAN-based fundus / OCT image synthesis, with our novel use of CAMs as conditional input of a high-resolution image-to-image translation GAN. The other method is Loose Pairing, which pairs a fundus image and an OCT image on the basis of their classes instead of eye identities. Experiments on a clinical dataset consisting of 1,099 color fundus images and 1,290 OCT images acquired from 1,099 distinct eyes verify the effectiveness of the proposed solution for multi-modal AMD categorization

Periostin identified as a potential biomarker of prostate cancer by iTRAQ-proteomics analysis of prostate biopsy

<p>Abstract</p> <p>Background</p> <p>Proteomics may help us better understand the changes of multiple proteins involved in oncogenesis and progression of prostate cancer(PCa) and identify more diagnostic and prognostic biomarkers. The aim of this study was to screen biomarkers of PCa by the proteomics analysis using isobaric tags for relative and absolute quantification(iTRAQ).</p> <p>Methods</p> <p>The patients undergoing prostate biopsies were classified into 3 groups according to pathological results: benign prostate hyperplasia (BPH, n = 20), PCa(n = 20) and BPH with local prostatic intraepithelial neoplasm(PIN, n = 10). Then, all the specimens from these patients were analyzed by iTRAQ and two-dimensional liquid chromatography-tandem mass spectrometry (2DLC-MS/MS). The Gene Ontology(GO) function and the transcription regulation networks of the differentially expressed were analyzed by MetaCore software. Western blotting and Immunohistochemical staining were used to analyze the interesting proteins.</p> <p>Result</p> <p>A total of 760 proteins were identified from 13787 distinct peptides, including two common proteins that enjoy clinical application: prostate specific antigen (PSA) and prostatic acid phosphatase(PAP). Proteins that expressed differentially between PCa and BPH group were further analyzed. Compared with BPH, 20 proteins were significantly differentially up-regulated (>1.5-fold) while 26 were significantly down-regulated in PCa(<0.66-fold). In term of GO database, the differentially expressed proteins were divided into 3 categories: cellular component(CC), molecular function (MF) and biological process(BP). The top 5 transcription regulation networks of the differentially expressed proteins were initiated through activation of SP1, p53, YY1, androgen receptor(AR) and c-Myc The overexpression of periostin in PCa was verified by western blotting and immunohistochemical staining.</p> <p>Conclusion</p> <p>Our study indicates that the iTRAQ technology is a new strategy for global proteomics analysis of the tissues of PCa. A significant up-regulation of periostin in PCa compared to BPH may provide clues for not only a promising biomarker for the prognosis of PCa but also a potential target for therapeutical intervention.</p