Evidence for Two-Component Jet in Sw J1644+57

The continued observations of Sw J1644+57 in X-ray and radio bands accumulated a rich data set to study the relativistic jet launched in this tidal disruption event. We find that the re-brightening feature in the radio light curve can be naturally explained by the two-component jet model. The possible origin of this structured jet are the Blandford-Znajek and Blandford-Payne mechanisms. We also show that this two-component jet model can interpret the two kinds of quasi-periodic variations in the X-ray light curve: a 200 second quasi-periodic oscillation (QPO) and a 2.7-day quasi-periodic variation. The latter is interpreted by a precessing outer jet launched near the Bardeen-Petterson radius of a warped disk. The $\sim$ 200s QPO could be associated with a second, narrower jet sweeping the observer line-of-sight periodically, which is launched from a spinning black hole in the misaligned direction with respect to the black hole's angular momentum.Comment: 6 pages, 3 figures. In proceedings of "Swift: 10 Years of Discovery" congress (Rome, 2-4 December 2014), PoS(SWIFT 10)17

A real time S1 assay at neutral pH based on graphene oxide quenched fluorescence probe

AbstractAs the extracellular nuclease of Aspergillus, S1 nuclease can split single and double-stranded DNA into oligo- or mononucleotides, while preferentially digests single-stranded nucleic acids. Furthermore, the existence of S1 can be the standard to identify Aspergillus and used to evaluate the severity of Aspergillosis. Herein, a simple and sensitive fluorescent sensing platform for S1 assay was developed based on the S1-induced DNA strand scission and the difference in affinity of graphene oxide (GO) for single-stranded DNA containing different bases. This platform was applied to monitor S1 activity and study the kinetics in real time. Results indicated that the detection limit is 0.5U/mL. The Km and kcat at 45°C, are 1.4±0.12μM and 0.6min−1, respectively. Moreover, by monitoring the effect of chemical drugs on S1 activity, we found that 2mM of erythromycin, sodium penicillin, carbenicillin disodium and ampicillin can inhibit S1 activity about 8%, 60%, 61% and 66%, respectively, while gentamycin sulfate is a stimulator. Overall, the assay platform based on graphene oxide quenched fluorescence probe is successfully constructed to study the enzymatic activity of S1 and used for screening antibiotics