Economic Implications of Tobacco Use for the State of Nebraska Government

We examine smoking-related expenditures for the state Medicaid program and for lost productivity among state government employees. The predicted number of new diagnoses of smoking-related illnesses among government employees ranged from 109 cases of kidney disease to 856 cases of arthritis and related diseases. We estimate over 6,000 lost workdays due to sick leave among currently smoking vs. non-smoking employees. Smoking-related illness is estimated to increase state budgetary expenditures on Medicaid by approximately $114.9 million annually.https://digitalcommons.unmc.edu/coph_policy_reports/1025/thumbnail.jp

Functional and Morphological Studies of Mitochondria Exposed to Undecagold Clusters: Biologic Surfaces Labeling with Gold Clusters

This study reports morphological and functional alterations observed in respiring isolated mitochondria when they are exposed to nonpenetrating, positive electrostatically charged synthetic undecagold clusters. Modification of the undecagold clusters positive charges change or prevent the functional effects and the binding to the outside surface of the mitochondria. The mitochondrial functional alterations are dependent on the oxidative phosphorylation capacity of the isolated organelles. The results of these experiments indicate that artificial undecagold may be useful to explore the molecular mechanisms of biological energy transducers which require electric charges separation, ionic fluxes, and electric surface properties

The use of simulation to prepare and improve responses to infectious disease outbreaks like COVID-19: practical tips and resources from Norway, Denmark, and the UK.

In this paper, we describe the potential of simulation to improve hospital responses to the COVID-19 crisis. We provide tools which can be used to analyse the current needs of the situation, explain how simulation can help to improve responses to the crisis, what the key issues are with integrating simulation into organisations, and what to focus on when conducting simulations. We provide an overview of helpful resources and a collection of scenarios and support for centre-based and in situ simulations

Boosting and Taming Wave Breakup in Second Harmonic Generation

Modulation instability is a universal phenomenon that can be found in a wide variety of nonlinear systems where, in the presence of a noise seed, peaks of random intensities can be generated. Several dynamical systems admit exact solutions in the form of breathers or solitons on a finite background. The vast majority of soliton studies has been restricted so far to one-dimensional systems. In contrast, the occurrences of localized structures in fully spatiotemporal systems has been only sporadically explored. In this work, we experimentally study the conditions for the wave-breaking of spatially extended optical beams in the process of second harmonic generation. Whenever the pump energy of the picosecond-long fundamental beam reaches a critical level, the beam shape at the second harmonic in a KTP crystal breaks into small filaments. These filaments exhibit extreme local intensity peaks, and their statistical distribution can be modified by the input energy of the fundamental beam. Moreover, by analyzing similar wave-breaking dynamics in a PPLN crystal in the presence of a higher nonlinear quadratic response, we observe that the spatial beam breaking may even gradually vanish as the laser intensity grows larger, leading to a spatial reshaping into a smooth and wider beam, accompanied by a substantial broadening of its temporal spectrum