135 research outputs found
Nerfbusters: Removing Ghostly Artifacts from Casually Captured NeRFs
Casually captured Neural Radiance Fields (NeRFs) suffer from artifacts such
as floaters or flawed geometry when rendered outside the camera trajectory.
Existing evaluation protocols often do not capture these effects, since they
usually only assess image quality at every 8th frame of the training capture.
To push forward progress in novel-view synthesis, we propose a new dataset and
evaluation procedure, where two camera trajectories are recorded of the scene:
one used for training, and the other for evaluation. In this more challenging
in-the-wild setting, we find that existing hand-crafted regularizers do not
remove floaters nor improve scene geometry. Thus, we propose a 3D
diffusion-based method that leverages local 3D priors and a novel density-based
score distillation sampling loss to discourage artifacts during NeRF
optimization. We show that this data-driven prior removes floaters and improves
scene geometry for casual captures.Comment: ICCV 2023, project page: https://ethanweber.me/nerfbuster
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Community Recommendations for Improving Sustainable Scientific Software Practices
Multiple focus groups were conducted to elicit perspectives from members of the Earth science informatics community on the sustainability of scientific software. Recommendations that the participants offered for near-term community actions and activities are described
Laboratory and Field Experimental Study of Underwater Inflatable Co-prime Sonar Array (UICSA)
This paper discusses the design and initial testing of a novel hydrophone array system dubbed the Underwater Inflatable Co-prime Sonar Array (UICSA). The UICSA will be a crucial component of an underwater deployable sensing network that can be rapidly deployed using compact autonomous underwater vehicles (AUVs). The UICSA initially is packed in a compact container to fit the payload space of an AUV. After deployment, the UICSA expands to its predetermined full length to acquire sensing data for source localization. More specifically, the mechanical compression of the UICSA is achieved through a non-rigid array support structure, which consists of flexible inflatable segments between adjoining hydrophones that are folded in order to package the UICSA for deployment. The system exploits compression in hydrophone layouts by utilizing a sparse array configuration, namely the co-prime array since it requires fewer hydrophones than a uniform linear array of the same length to estimate a given number of sources. With two-way compression, the storage, handling, and transportation of the compactly designed UICSA is convenient, particularly for the AUVs with limited payload space. The deployment concept and process are discussed, as well as the various UICSA designs of different support structures are described. A comparison of the various mechanical designs is presented and a novel hybrid-based expansion prototype is documented in detail. Laboratory study results of the UICSA prototype are presented that include water-swollen material tests in a pressurized environment and water tank validation of the inflation process. The UICSA prototype also has been deployed in the Harbor Branch channel to validate the performance, the related field test details and source localization results
Utah State University Youth Conservatory Spring Graduation
An event for all the participants in the Utah State University Youth Conservatory to perform piano pieces that they practiced and mastered in the months prior.
The Utah State University Youth Conservatory accepts youth up to age 18 and provides them private lessons to develop their piano skills.https://digitalcommons.usu.edu/music_programs/1114/thumbnail.jp
Report on the Third Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE3)
This report records and discusses the Third Workshop on Sustainable Software
for Science: Practice and Experiences (WSSSPE3). The report includes a
description of the keynote presentation of the workshop, which served as an
overview of sustainable scientific software. It also summarizes a set of
lightning talks in which speakers highlighted to-the-point lessons and
challenges pertaining to sustaining scientific software. The final and main
contribution of the report is a summary of the discussions, future steps, and
future organization for a set of self-organized working groups on topics
including developing pathways to funding scientific software; constructing
useful common metrics for crediting software stakeholders; identifying
principles for sustainable software engineering design; reaching out to
research software organizations around the world; and building communities for
software sustainability. For each group, we include a point of contact and a
landing page that can be used by those who want to join that group's future
activities. The main challenge left by the workshop is to see if the groups
will execute these activities that they have scheduled, and how the WSSSPE
community can encourage this to happen
Nerfstudio: A Modular Framework for Neural Radiance Field Development
Neural Radiance Fields (NeRF) are a rapidly growing area of research with
wide-ranging applications in computer vision, graphics, robotics, and more. In
order to streamline the development and deployment of NeRF research, we propose
a modular PyTorch framework, Nerfstudio. Our framework includes plug-and-play
components for implementing NeRF-based methods, which make it easy for
researchers and practitioners to incorporate NeRF into their projects.
Additionally, the modular design enables support for extensive real-time
visualization tools, streamlined pipelines for importing captured in-the-wild
data, and tools for exporting to video, point cloud and mesh representations.
The modularity of Nerfstudio enables the development of Nerfacto, our method
that combines components from recent papers to achieve a balance between speed
and quality, while also remaining flexible to future modifications. To promote
community-driven development, all associated code and data are made publicly
available with open-source licensing at https://nerf.studio.Comment: Project page at https://nerf.studi
ROS1 genomic rearrangements are rare actionable drivers in microsatellite stable colorectal cancer
c-Ros oncogene 1, receptor tyrosine kinase (ROS1) genomic rearrangements have been reported previously in rare cases of colorectal cancer (CRC), yet little is known about the frequency, molecular characteristics, and therapeutic vulnerabilities of ROS1-driven CRC. We analyzed a clinical dataset of 40 589 patients with CRC for ROS1 genomic rearrangements and their associated genomic characteristics (Foundation Medicine, Inc [FMI]). We moreover report the disease course and treatment response of an index patient with ROS1-rearranged metastatic CRC. ROS1 genomic rearrangements were identified in 34 (0.08%) CRC samples. GOPC-ROS1 was the most common ROS1 fusion identified (11 samples), followed by TTC28-ROS1 (3 samples). Four novel 5' gene partners of ROS1 were identified (MCM9, SRPK1, EPHA6, P4HA1). Contrary to previous reports on fusion-positive CRC, ROS1-rearrangements were found exclusively in microsatellite stable (MSS) CRCs. KRAS mutations were significantly less abundant in ROS1-rearranged vs ROS1 wild type cases. The index patient presented with chemotherapy-refractory metastatic right-sided colon cancer harboring GOPC-ROS1. Molecularly targeted treatment with crizotinib induced a rapid and sustained partial response. After 15 months on crizotinib disseminated tumor progression occurred and KRAS Q61H emerged in tissue and liquid biopsies. ROS1 rearrangements define a small, yet therapeutically actionable molecular subgroup of MSS CRC. In summary, the high prevalence of GOPC-ROS1 and noncanonical ROS1 fusions pose diagnostic challenges. We advocate NGS-based comprehensive molecular profiling of MSS CRCs that are wild type for RAS and BRAF and patient enrollment in precision trials.
Keywords: ROS1 rearrangement; acquired resistance; colorectal cancer; crizotinib; molecular subgroups; precision treatmen
ROS1 genomic rearrangements are rare actionable drivers in microsatellite stable colorectal cancer.
c-Ros oncogene 1, receptor tyrosine kinase (ROS1) genomic rearrangements have been reported previously in rare cases of colorectal cancer (CRC), yet little is known about the frequency, molecular characteristics, and therapeutic vulnerabilities of ROS1-driven CRC. We analyzed a clinical dataset of 40 589 patients with CRC for ROS1 genomic rearrangements and their associated genomic characteristics (Foundation Medicine, Inc [FMI]). We moreover report the disease course and treatment response of an index patient with ROS1-rearranged metastatic CRC. ROS1 genomic rearrangements were identified in 34 (0.08%) CRC samples. GOPC-ROS1 was the most common ROS1 fusion identified (11 samples), followed by TTC28-ROS1 (3 samples). Four novel 5' gene partners of ROS1 were identified (MCM9, SRPK1, EPHA6, P4HA1). Contrary to previous reports on fusion-positive CRC, ROS1-rearrangements were found exclusively in microsatellite stable (MSS) CRCs. KRAS mutations were significantly less abundant in ROS1-rearranged vs ROS1 wild type cases. The index patient presented with chemotherapy-refractory metastatic right-sided colon cancer harboring GOPC-ROS1. Molecularly targeted treatment with crizotinib induced a rapid and sustained partial response. After 15 months on crizotinib disseminated tumor progression occurred and KRAS Q61H emerged in tissue and liquid biopsies. ROS1 rearrangements define a small, yet therapeutically actionable molecular subgroup of MSS CRC. In summary, the high prevalence of GOPC-ROS1 and noncanonical ROS1 fusions pose diagnostic challenges. We advocate NGS-based comprehensive molecular profiling of MSS CRCs that are wild type for RAS and BRAF and patient enrollment in precision trials
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