Long Run Health Impacts of Income Shocks: Wine and Phylloxera in 19th Century France

This paper provides estimates of the long-term effects on height and health of a large income shock experienced in early childhood. Phylloxera, an insect that attacks the roots of grape vines, destroyed 40% of French vineyards between 1863 and 1890, causing major income losses among wine growing families. Because the insects spread slowly from the southern coast of France to the rest of the country, Phylloxera affected different regions in different years. We exploit the regional variation in the timing of this shock to identify its effects. We examine the effects on the adult height, health, and life expectancy of children born in the years and regions affected by the Phylloxera. The shock decreased long run height, but it did not affect other dimensions of health, including life expectancy. We find that, at age 20, those born in affected regions were about 1.8 millimeters shorter than others. This estimate implies that children of wine-growing families born when the vines were affected in their regions were 0.6 to 0.9 centimeters shorter than others by age 20. This is a significant effect since average heights grew by only 2 centimeters in the entire 19th century. However, we find no other effect on health, including infant mortality, life expectancy, and morbidity by age 20.

Essays in labor and health economics

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Economics, September 2007."September 2006."Includes bibliographical references.This dissertation consists of three essays in empirical labor and health economics. The first chapter examines how the amount of time devoted to a leisure activity varies in response to temporary changes in the price of that activity. Specifically, I estimate the effect of changes in expected winnings in an online poker game on the probability that players quit playing. I find that expected winnings have a large negative effect on the probability that a player quits playing poker. A one dollar increase in expected winnings decreases the probability that a player quits playing altogether by 0.5 percentage points, compared to the mean of 1.1 percentage points. This corresponds to a price elasticity of demand for poker of -0.14. The second chapter develops and tests a model of how college students choose their field of study. The model combines features from learning and human capital models and captures several stylized facts from the empirical literature on choice of college major. I test the model's predictions using High School and Beyond data. I find three results that generally agree with the model's predictions. First, students with higher levels of ability choose majors with higher average earnings. Second, students who receive low grades in college are more likely to change their field of study. Third, students who switch majors in college subsequently earn less than students who do not change majors, but this difference is primarily due to major-switchers obtaining degrees in low-paying fields. The third chapter, coauthored with Abhijit Banerjee, Esther Duflo and Gilles Postel-Vinay, provides estimates of the long-term effects on height and health of a large income shock experienced in early childhood.(cont.) Phylloxera, an insect that attacks the roots of grape vines, destroyed 40% of French vineyards between 1863 and 1890, causing major income losses among wine growing families. We exploit the regional variation in the timing of this shock to identify its effects. We find that, at age 20, those born in affected regions were about 1.8 millimeters shorter than others. This estimate implies that children of wine-growing families born when the vines were affected in their regions were 0.6 to 0.9 centimeters shorter than others by age 20. This is a significant effect since average heights grew by only 2 centimeters in the entire 19th century.by Timothy M. Watts.Ph.D

Cadaveric Spinal Surgery Simulation: A Comparison of Cadaver Types

Study Design: Single-blinded study. Objective: To assess the suitability of three types of cadaver for simulating pedicle screw insertion and establish if there is an ideal. Methods: Three types of cadaver-Thiel-embalmed, Crosado-embalmed, and formaldehyde-embalmed-were draped and the spines exposed. Experienced surgeons were asked to place pedicle screws in each cadaver and give written questionnaire feedback using a modified Likert scale. Soft tissue and bony properties were assessed, along with the role of simulation in spinal surgery training. Results: The Thiel cadaver rated highest for soft tissue feel and appearance with a median score of 6 for both (range 2 to 7). The Crosado cadaver rated highest for bony feel, with a median score of 6 (range 2 to 7). The formaldehyde cadaver rated lowest for all categories with median scores of 2, 2.5, and 3.5, respectively. All surgeons felt pedicle screw insertion should be learned in a simulated setting using human cadavers. Conclusion: Thiel and Crosado cadavers both offered lifelike simulation of pedicle screw insertion, with each having advantages depending on whether the focus is on soft tissue approach or technical aspects of bony screw insertion. Both cadaver types offer the advantage of long life span, unlike fresh frozen tissue, which means cadavers can be used multiple times, thus reducing the costs

Structural Classification of Metal Complexes with Three-Coordinate Centres

Attempts to describe the geometry about three-coordinate silver(I) complexes have proven difficult because interatomic angles generally vary wildly and there is no adequate or readily available classification system found in the literature. A search of the Cambridge Structural Database shows that complexes formed between any metal centre and three non-metal donors (18001 examples) usually adopt geometries that are quite different than ideal ‘textbook’ extremes of either trigonal planar (∼4% with α = β = γ = 120 ± 2°), T-shaped (∼0.05% with α = 180 ± 2°, β = γ = 90 ± 2°), or trigonal pyramidal (∼0.3% with α = β = γ = 110 ± 2°). Moreover, there are multiple variations of “Y-type” and “other” shapes that require elaboration. Thus, to assist in future structural descriptions, we developed a classification system that spans all known and yet-to-be-discovered three-coordinate geometries. A spreadsheet has also been constructed that utilizes the “shape-space” approach to extract the structural description from a user input of three angles about a tri-coordinate centre and the number of atoms in a plane. The structures of two silver(I) complexes of new N-donor ligands p-NH2C6H4C6H4CH(pz = pyrazol-1-yl)2, L1, and 2-ferrocenyl-4,5-di(2-pyridyl)imidazole, L2, illustrate the utility of this classification system

Adrenergic agonists induce heterologous sensitization of adenylate cyclase in NS20Y-D2L cells

AbstractAdenylate cyclase activity in NS20Y cells expressing D2L dopamine receptors was examined following chronic treatment with norepinephrine and epinephrine. Initial acute experiments revealed that both norepinephrine and epinephrine inhibited forskolin-stimulated cyclic AMP accumulation via D2 receptors. Furthermore, chronic (18 h) activation of D2 dopamine receptors by norepinephrine or epinephrine induced a marked increase (>10-fold) in subsequent forskolin-stimulated cyclic AMP accumulation. This heterologous sensitization of adenylate cyclase activity was blocked by D2 dopamine receptor antagonists and by pertussis toxin pretreatment. In contrast, concurrent activation of Gαs or adenylate cyclase did not appear to alter noradrenergic agonist-induced sensitization

Mining and Analyzing the Italian Parliament: Party Structure and Evolution

The roll calls of the Italian Parliament in the XVI legislature are studied by employing multidimensional scaling, hierarchical clustering, and network analysis. In order to detect changes in voting behavior, the roll calls have been divided in seven periods of six months each. All the methods employed pointed out an increasing fragmentation of the political parties endorsing the previous government that culminated in its downfall. By using the concept of modularity at different resolution levels, we identify the community structure of Parliament and its evolution in each of the considered time periods. The analysis performed revealed as a valuable tool in detecting trends and drifts of Parliamentarians. It showed its effectiveness at identifying political parties and at providing insights on the temporal evolution of groups and their cohesiveness, without having at disposal any knowledge about political membership of Representatives.Comment: 27 pages, 14 figure