Collaborating with Teaching Faculty on Transparent Assignment Design

In light of a campus-wide curricular change at the University of Nevada, Las Vegas (UNLV), the University Libraries created Faculty Institutes to build capacity for effective teaching and assessment practices campus-wide. The UNLV Libraries Faculty Institutes are multi-day workshops designed and delivered by librarians to help teaching faculty create courses and assignments that are research-rich and closely aligned with the newly launched General Education learning outcomes. This chapter provides the situational factors leading to the overhaul of General Education at UNLV and how librarians leveraged this opportunity to maximize their role as experts in information literacy and instructional design. This chapter also describes how librarians used instructional design principles for creating significant learning experiences1 and transparent assignment design2 to guide the development and delivery of the Faculty Institutes. Finally, we draw on our experiences to suggest that the interdisciplinarity and specialized skills of librarians make us particularly poised to be leaders of curricular transformation at our institutions

The Architecture of Eastern\u27s Old Main

https://thekeep.eiu.edu/eiu_history/1008/thumbnail.jp

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed metastatic sites, might offer new therapeutic approaches for limiting tumour recurrence. The ability to track the evolutionary dynamics of early-stage lung cancer non-invasively in circulating tumour DNA (ctDNA) has not yet been demonstrated. Here we use a tumour-specific phylogenetic approach to profile the ctDNA of the first 100 TRACERx (Tracking Non-Small-Cell Lung Cancer Evolution Through Therapy (Rx)) study participants, including one patient who was also recruited to the PEACE (Posthumous Evaluation of Advanced Cancer Environment) post-mortem study. We identify independent predictors of ctDNA release and analyse the tumour-volume detection limit. Through blinded profiling of postoperative plasma, we observe evidence of adjuvant chemotherapy resistance and identify patients who are very likely to experience recurrence of their lung cancer. Finally, we show that phylogenetic ctDNA profiling tracks the subclonal nature of lung cancer relapse and metastasis, providing a new approach for ctDNA-driven therapeutic studies