8,649 research outputs found

    Microwave attenuation and brightness temperature due to the gaseous atmosphere: A comparison of JPL and CCIR values

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    A sophisticated but flexible radiative transfer program designed to assure internal consistency was used to produce brightness temperature (sky noise temperature in a given direction) and gaseous attenuation curves. The curves, derived from atmospheric models, were compared and a new set was derived for a specified frequency range

    ISO spectroscopy of circumstellar dust in 14 Herbig Ae/Be systems: towards an understanding of dust processing

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    We present Infrared Space Observatory (ISO) spectra of fourteen isolated Herbig Ae/Be (HAEBE) stars, to study the characteristics of their circumstellar dust. These spectra show large star-to-star differences, in the emission features of both carbon-rich and oxygen-rich dust grains. The IR spectra were combined with photometric data ranging from the UV through the optical into the sub-mm region. We defined two key groups, based upon the spectral shape of the infrared region. The derived results can be summarized as follows: (1) the continuum of the IR to sub-mm region of all stars can be reconstructed by the sum of a power-law and a cool component, which can be represented by a black body. Possible locations for these components are an optically thick, geometrically thin disc (power-law component) and an optically thin flared region (black body); (2) all stars have a substantial amount of cold dust around them, independent of the amount of mid-IR excess they show; (3) also the near-IR excess is unrelated to the mid-IR excess, indicating different composition/location of the emitting material; (4) remarkably, some sources lack the silicate bands; (5) apart from amorphous silicates, we find evidence for crystalline silicates in several stars, some of which are new detections; (6) PAH bands are present in at least 50% of our sample, and their appearance is slightly different from PAHs in the ISM; (7) PAH bands are, with one exception, not present in sources which only show a power-law continuum in the IR; their presence is unrelated to the presence of the silicate bands; (8) the dust in HAEBE stars shows strong evidence for coagulation; this dust processing is unrelated to any of the central star properties (such as age, spectral type and activity).Comment: 15 pages, accepted by A&

    Sequential star formation in IRAS 06084-0611 (GGD 12-15): From intermediate-mass to high-mass stars

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    Context. The formation and early evolution of high- and intermediate-mass stars towards the main sequence involves the interplay of stars in a clustered and highly complex environment. To obtain a full census of this interaction, the Formation and Early evolution of Massive Stars (FEMS) collaboration studies a well-selected sample of 10 high-mass star-forming regions. Aims. In this study we examine the stellar content of the high-mass star-forming region centered on IRAS 06084-0611 in the Monoceros R2 cloud. Methods. Using the near-infrared H- and K-band spectra from the VLT/SINFONI instrument on the ESO Very Large Telescope (VLT)and photometric near-infrared NTT/SOFI, 2MASS and Spitzer/IRAC data, we were able to determine the spectral types for the most luminous stars in the cluster. Results. Two very young and reddened massive stars have been detected by SINFONI: a massive Young Stellar Object (YSO) con- sistent with an early-B spectral type and a Herbig Be star. Furthermore, stars of spectral type G and K are detected while still in the Pre-Main Sequence (PMS) phase. We derive additional properties such as temperatures, extinctions, radii and masses. We present a Hertzsprung-Russell diagram and find most objects having intermediate masses between \sim1.5-2.5 M\odot. For these stars we derive a median cluster age of \sim4 Myr. Conclusions. Using Spitzer/IRAC data we confirm earlier studies that the younger class 0/I objects are centrally located while the class II objects are spread out over a larger area, with rough scale size radii of \sim0.5 pc and \sim1.25 pc respectively. Moreover, the presence of a massive YSO, an ultracompact H ii region and highly reddened objects in the center of the cluster suggest a much younger age of < 1 Myr. A possible scenario for this observation would be sequential star formation along the line of sight; from a cluster of intermediate-mass to high-mass stars.Comment: 14 pages, 10 figures, 2 tables. Astronomy and Astrophysic

    STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection.

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    UnlabelledSTING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces a STING-dependent type I IFN response in infected cells, yet the IFN-inducing ligand remains unknown. In this report, we provide evidence that Chlamydia synthesizes cyclic di-AMP (c-di-AMP), a nucleic acid metabolite not previously identified in Gram-negative bacteria, and that this metabolite is a prominent ligand for STING-mediated activation of IFN responses during infection. We used primary mouse lung fibroblasts and HEK293T cells to compare IFN-β responses to Chlamydia infection, c-di-AMP, and other type I IFN-inducing stimuli. Chlamydia infection and c-di-AMP treatment induced type I IFN responses in cells expressing STING but not in cells expressing STING variants that cannot sense cyclic dinucleotides but still respond to cytoplasmic DNA. The failure to induce a type I IFN response to Chlamydia and c-di-AMP correlated with the inability of STING to relocalize from the endoplasmic reticulum to cytoplasmic punctate signaling complexes required for IFN activation. We conclude that Chlamydia induces STING-mediated IFN responses through the detection of c-di-AMP in the host cell cytosol and propose that c-di-AMP is the ligand predominantly responsible for inducing such a response in Chlamydia-infected cells.ImportanceThis study shows that the Gram-negative obligate pathogen Chlamydia trachomatis, a major cause of pelvic inflammatory disease and infertility, synthesizes cyclic di-AMP (c-di-AMP), a nucleic acid metabolite that thus far has been described only in Gram-positive bacteria. We further provide evidence that the host cell employs an endoplasmic reticulum (ER)-localized cytoplasmic sensor, STING (stimulator of interferon [IFN] genes), to detect c-di-AMP synthesized by Chlamydia and induce a protective IFN response. This detection occurs even though Chlamydia is confined to a membrane-bound vacuole. This raises the possibility that the ER, an organelle that innervates the entire cytoplasm, is equipped with pattern recognition receptors that can directly survey membrane-bound pathogen-containing vacuoles for leaking microbe-specific metabolites to mount type I IFN responses required to control microbial infections

    What Does Written Reflection Reveal About Novice Teachers’ Knowledge, Beliefs, and Skills Related to Literacy Assessment?

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    Assessment of literacy learning has been a long-standing focus for future teachers in elementary education. Teacher educators use ongoing written reflection to promote learning before, during, and after coursework and field experiences. In this study, the researchers examined the effects of ongoing written reflection on two groups of novice teachers’ knowledge, beliefs, and skills about literacy assessment in a semester-long graduate-level literacy assessment course with embedded fieldwork. First, the researchers conducted qualitative and descriptive analyses to examine what novice teachers reflected about in their ongoing written reflections. Second, they conducted comparative analyses to examine the extent to which the two groups differed in what they reflected about. Qualitative and descriptive analysis of written reflections revealed four prominent categories in which novice teachers reflected: (a) content knowledge related to literacy assessment, (b) beliefs about literacy assessment, (c) empathy and perspective-taking in the literacy assessment and instruction process, and (d) instructional planning and decision making. Comparative analyses revealed significant differences between the two groups of novice teachers in all four categories

    The association between child and adolescent emotional disorder and poor attendance at school: a systematic review protocol.

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    This is the final version of the article. Available from BioMed Central via the DOI in this record.BACKGROUND: Anxiety and depression are common in young people and are associated with a range of adverse outcomes. Research has suggested a relationship between emotional disorder and poor school attendance, and thus poor attendance may serve as a red flag for children at risk of emotional disorder. This systematic review aims to investigate the association between child and adolescent emotional disorder and poor attendance at school. METHODS: We will search electronic databases from a variety of disciplines including medicine, psychology, education and social sciences, as well as sources of grey literature, to identify any quantitative studies that investigate the relationship between emotional disorder and school attendance. Emotional disorder may refer to diagnoses of mood or anxiety disorders using standardised diagnostic measures, or measures of depression, anxiety or "internalising symptoms" using a continuous scale. Definitions for school non-attendance vary, and we aim to include any relevant terminology, including attendance, non-attendance, school refusal, school phobia, absenteeism and truancy. Two independent reviewers will screen identified papers and extract data from included studies. We will assess the risk of bias of included studies using the Newcastle-Ottawa Scale. Random effects meta-analysis will be used to pool quantitative findings when studies use the same measure of association, otherwise a narrative synthesis approach will be used. DISCUSSION: This systematic review will provide a detailed synthesis of evidence regarding the relationship between childhood emotional disorder and poor attendance at school. Understanding this relationship has the potential to assist in the development of strategies to improve the identification of and intervention for this vulnerable group. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016052961.This research is being carried out as part of a PhD studentship funded by the University of Exeter Medical School
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