210 research outputs found

    Reflection on the reflective ethics of charity

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    This article is a reflection on the NSU Winter Symposium of March 2020, entitled ‘Feminism and Hospitality: Religious and Critical Perspectives in dialogue with a Secular Age’. It contends with moral judgments which regard charity as an act of alienation from the other and as a reiteration of hierarchies of power. Instead of this conceptualisation, I propose an ethics of charity in terms of an ethics of the reflective agency of otherness. This ethics of charity entails acts of aid for an other which stem from the recognition of the agency pertaining to both parties. It will be shown how this recognition of agency, and the reciprocity it entails, is critical for the success of the charitable endeavour in two ways: first, for the manifestation of the act itself of aiding and providing for another; second, for the assertion of the other’s own agency through the reciprocal act of charity

    Paradox of Stubbornness: The Epistemology of Stereotypes Regarding Women

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    The discrepancy between individual women and the stereotypes attributed to the group as a ‎whole has become progressively greater and more explicit over the course of history. The stereotypes remain the same age-old ‎allegations whilst the ‎developments in the occupations of women and the traits they have opportunity to express have increased the distance between women and those ascribed traits. Stereotypes’ abstention from revision in light of contrary evidence constitutes an epistemic paradox for it entails conflict between the stereotypical knowledge and empirical evidence, as well as between the stereotypical knowledge and other empirical knowledges. This paradox of stubbornness also raises the question as to the epistemic source of stereotypes. For, people at young ages encounter evidence which should have formed a more complex knowledge regarding women rather than the pervasive stereotypical knowledge. It is this extremity of absurdness of stereotypes regarding women that is utile to understanding stereotypes as a whole. The epistemic paradox that is engrained in all stereotypes is exposed uncompromisingly by this group. The paradox cannot be dismissed with excuses of having a small basis of evidence, such as may be said regarding other social groups with which one may have had minimal or no contact. Thus, stereotypes of women provide a limit case to understanding the epistemology of this paradoxical form of knowledge. The traits and epistemic phenomena which render stereotypes epistemically puzzling and intriguing is the relationship between knowledges. Stereotypical knowledge regarding women as a group conflict with one’s experience-founded knowledges of particular women, deeming the corporate body of knowledge incoherent. Quine’s theory of knowledge, with its holistic empirical approach endorsing conceptual schemes, provides fertile ground for this analysis. The novelty in his account is his establishment of the criteria of coherency, which shifts the focal point of epistemic inquiry away from the adequacy of individual knowledges with empirical evidence to the intra-knowledge relationships themselves. In his empiricism, Quine rather examines the interactions between knowledges and the overarching coherence of the body of knowledge as a holistic unit. Quine creates place in his account for mechanism which provide for the epistemic incongruences of stubbornness and conflict found between stereotypical knowledges and empirical evidence. These very mechanisms are what this paper requests to examine. Quine, ultimately, formulates knowledge as a collectively held fabric consisting of relations and of posits – socially constructed mechanisms which are empirically-irreducible and implemented pragmatically for the organisation of empirical evidence. According to Quine, the fabric formation is a conceptual scheme sourced in social heritage. People are bestowed with an eclectic framework of ‎knowledge to pragmatically merge between an inherited, collective conceptual scheme and the personally experienced empirical evidence. This paper will delve into Quine’s fabric of knowledge, its relations, and inner-mechanisms. The finding of stereotypes to be an age-old posit entrenched pragmatically – thus stubbornly – in the collective conceptual scheme, will explain the epistemic paradoxes they entail and offer insight to their revision in light of empiric reality and its women

    Yield and clinical efficacy of funduscopic examinations performed in the pediatric emergency room

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    Abstract Consultations by ophthalmologists to rule out papilledema are frequently requested by emergency room (ER) physicians. The clinical setting and optimal timing for examination are not well established, and the impact on patient management is unclear. We evaluated the yield of emergency funduscopic examinations, aiming at establishing the optimal timing and efficacy of the consultation. The medical records of all children aged 0-18 years referred for funduscopic examinations from the ER between June 2010 and May 2011 were reviewed. Of 19,772 ER visits, 1,920 (9.7 %) were seen by an ophthalmologist and 479 (2.4 %) to rule out papilledema. Headache (44.5 %) and head trauma (18.4 %) were the most common indications. Sixty percent of the 479 patients had been symptomatic for <24 h, all having normal eye exams. Only 6/479, with diverse etiologies, depicted papilledema. Among these six children, visual complaints associating with headache were statistically significant to suggest the presence of papilledema (p =0.014). Seventy-one of the 479 children underwent neuroimaging studies despite normal funduscopic examinations. A single tumor case (medulloblastoma), symptomatic for weeks, had normal funduscopy. Conclusion: The vast majority of ER consultations to rule out papilledema show normal findings, particularly among children with signs and symptoms lasting for <24 h. The yield of funduscopy may be higher if visual disturbances are reported. If neuroimaging studies are considered, emergency room ophthalmological consultation is probably not warranted, except for young infants with neurological signs and symptoms in whom retinal hemorrhages suggestive of physical abuse must be ruled out

    Video Capsule Retention in a Zenker Diverticulum

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    We report the case of a video capsule endoscope lodged within a Zenker diverticulum. The system that was equipped with a real-time viewer showed an unchanging image unlike esophageal or gastric mucosa, suggesting that the capsule was elsewhere. The presence of cervical discomfort suggested video capsule retention in a Zenker diverticulum. The capsule was removed endoscopically and reinserted using a hood-assisted endoscope and the procedure was completed

    The CHOLEGAS study: multicentric randomized, blinded, controlled trial of gastrectomy plus prophylactic cholecystectomy versus gastrectomy only, in adults submitted to Gastric cancer surgery with curative intent

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    <p>Abstract</p> <p>Background</p> <p>The incidence of gallstones and gallbladder sludge is known to be higher in patients after gastrectomy than in general population. This higher incidence is probably related to surgical dissection of the vagus nerve branches and the anatomical gastrointestinal reconstruction. Therefore, some surgeons perform routine concomitant cholecystectomy during standard surgery for gastric malignancies. However, not all the patients who are diagnosed to have cholelithiasis after gastric cancer surgery will develop symptoms or require additional surgical treatments and a standard laparoscopic cholecystectomy is feasible even in those patients who underwent previous gastric surgery. At the present, no randomized study has been published and the decision of gallbladder management is left to each surgeon preference.</p> <p>Design</p> <p>The study is a randomized controlled investigation. The study will be performed in the General and Oncologic Surgery, Department of Oncology – Azienda Ospedaliero-Universitaria Careggi – Florence – Italy, a large teaching institution, with the participation of all surgeons who accept to be involved in, together with other Italian Surgical Centers, on behalf of the GIRCG (Italian Research Group for Gastric Cancer).</p> <p>The patients will be randomized into two groups: in the first group the patient will be submitted to prophylactic cholecystectomy during standard surgery for curable gastric cancer (subtotal or total gastrectomy), while in the second group he/she will be submitted to standard gastric surgery only.</p> <p>Trial Registration</p> <p>ClinicalTrials.gov ID. NCT00757640</p

    Topiramate Monotherapy in Infantile Spasm

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    Infantile spasm is an age-related refractory epilepsy. Topiramate is a new anticonvulsant with multiple mechanisms of action, and it may be effective for treating pediatric epilepsies. To evaluate the efficacy and tolerability of first-line topiramate treatment for infantile spasm, 20 patients received topiramate monotherapy during this study. They were treated with an initial dose of 1 mg/kg/day, with a progressive titration of 1 mg/kg a week until their spasms were controlled and a maximum dose of 12 mg/kg/day was achieved. The evaluation of the treatment efficacy was based on the spasm frequency data that was obtained by the scalp and video-EEG, and by the parental count of spasm. Thirty percent of the subjects became spasm-free during the study. Six of 20 subjects (30%) had cessation of spasm and disappearance of hypsarrhythmia as seen via the video EEG; four (50%) of eight idiopathic patients had a response, whereas two (17%) of 12 patients with symptomatic infantile spasm responded. Seventy of the patients, including the spasm-free patients, had a reduction in their seizure frequency of more than 50%, and 10% of the patients had a reduction in their seizure frequency of less than 50%. The clusters of spasm frequency decreased from 10.6 ± 8.5 to 3.5 ± 1.4 clusters/day. Topiramate is effective and tolerated in those patients suffering from infantile spasm. Our results suggest that this drug should be considered as a new first-line drug for treating infantile spasm

    Role of Brain Inflammation in Epileptogenesis

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    Inflammation is known to participate in the mediation of a growing number of acute and chronic neurological disorders. Even so, the involvement of inflammation in the pathogenesis of epilepsy and seizure-induced brain damage has only recently been appreciated. Inflammatory processes, including activation of microglia and astrocytes and production of proinflammatory cytokines and related molecules, have been described in human epilepsy patients as well as in experimental models of epilepsy. For many decades, a functional role for brain inflammation has been implied by the effective use of anti-inflammatory treatments, such as steroids, in treating intractable pediatric epilepsy of diverse causes. Conversely, common pediatric infectious or autoimmune diseases are often accompanied by seizures during the course of illness. In addition, genetic susceptibility to inflammation correlated with an increased risk of epilepsy. Mounting evidence thus supports the hypothesis that inflammation may contribute to epileptogenesis and cause neuronal injury in epilepsy. We provide an overview of the current knowledge that implicates brain inflammation as a common predisposing factor in epilepsy, particularly childhood epilepsy
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