Corrections to the Nuclear Axial Vector Coupling in a Nuclear Medium

We examine further corrections to the time component of the axial vector coupling constant in a nuclear medium. The dominant correction is that of exchange currents. The corrections we examine make the remaining discrepancy worse.Comment: 6 pages, 2 figure

Isofrequency pairing of geodesic orbits in Kerr geometry

Abstract ? Bound geodesic orbits around a Kerr black hole can be parametrized by three constants of the motion: the (specific) orbital energy, angular momentum, and Carter constant. Generically, each orbit also has associated with it three frequencies, related to the radial, longitudinal, and (mean) azimuthal motions. Here, we note the curious fact that these two ways of characterizing bound geodesics are not in a one-to-one correspondence. While the former uniquely specifies an orbit up to initial conditions, the latter does not: there is a (strong-field) region of the parameter space in which pairs of physically distinct orbits can have the same three frequencies. In each such isofrequency pair, the two orbits exhibit the same rate of periastron precession and the same rate of Lense-Thirring precession of the orbital plane, and (in a certain sense) they remain “synchronized” in phase.<br/

Determination of the proper operating range for the CAFCA IIB fuel cycle model

Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2007.Includes bibliographical references (p. 26).The fuel cycle simulation tool, CAFCA II was previously modified to produce the most recent version, CAFCA IIB. The code tracks the mass distribution of transuranics in the fuel cycle in one model and also projects costs for various fuel cycle schemes. The mass distribution model also shows the schedule for deployment of recycling plants. All of these models are dependent on user inputs, some of which specify advanced technology type and capacity, plant lifetime and recycling facility capacity. The behavior of CAFCA IIB resulting from the most recent modifications are investigated through extensive modeling of various nuclear fuel cycles. By re-modeling nuclear fuel cycle schemes in CAFCA IIB that were modeled in CAFCA II, the two results can be compared and conclusions can be drawn as to an discrepancies between the two. Specifically, the results representing TRU mass balance accumulation in the system, spent fuel separation plant construction and fertile free fuel spent fuel reprocessing plant construction are compared. Thus, these new runs will substantiate the accuracy of past work and expand the number of reactor options that have been evaluated by CAFCA IIB. Additionally, the new data help pinpoint the operating range for CAFCA IIB in which the code is accurate. Overall, none of the results from the same conditions in CAFCA II and CAFCA IIB matched up perfectly. Therefore, in an effort to further evaluate the effectiveness of CAFCA IIB, the plant lifetime input is tested in order to determine system sensitivities to that factor. This is done by modeling of nuclear fuel cycles while varying that single input, and comparing the results to the base or control case. Results suggest that different combinations of the various parameters are ideal for each different strategy of reactor type.by Jamie Warburton.S.B

Arbuscular mycorrhizal fungi as mediators of ecosystem responses to nitrogen deposition: A trait-based predictive framework

Anthropogenic nitrogen (N) deposition is exposing plants and their arbuscular mycorrhizal fungi (AMFs) to elevated N availability, often leading to shifts in communities of AMF. However, physiological trade-offs among AMF taxa in their response to N enrichment vs the ability to acquire other soil nutrients could have negative effects on plant and ecosystem productivity. It follows that information on the functional traits of AMF taxa can be used to generate predictions of their potential role in mediating ecosystem responses to N enrichment. Arbuscular mycorrhizal fungi taxa that produce extensive networks of external hyphae should forage for N and phosphorus (P) more effectively, but these services incur greater carbon (C) costs to the plant. If N enrichment ameliorates plant nutrient limitation, then plants may reduce C available for AMF, which in turn could eliminate AMF taxa with large extensive external hyphae from the soil community. As a result, the remaining AMF taxa may confer less P benefit to their host plants. Using a synthesis of data from the literature, we found that the ability of a taxon to persist in the face of increasing soil N availability was particularly high in isolates from the genus Glomus, but especially low among the Gigasporaceae. Across AMF genera, our data support the prediction that AMF with a tolerance for high soil N may confer a lower P benefit to their host plant. Relationships between high N tolerance and production of external hyphae were mixed. Synthesis. If the relationship between N tolerance and plant P benefit is widespread, then shifts in arbuscular mycorrhizal fungi communities associated with N deposition could have negative consequences for the ability of plants to acquire P and possibly other nutrients via a mycorrhizal pathway. Based on this relationship, we predict that arbuscular mycorrhizal fungi responses could constrain net primary productivity in P-limited ecosystems exposed to N enrichment. This prediction could be tested in future empirical and modelling studies

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation.

The human genome is structurally organized in three-dimensional space to facilitate functional partitioning of transcription. We learned that the latent episome of the human Epstein-Barr virus (EBV) preferentially associates with gene-poor chromosomes and avoids gene-rich chromosomes. Kaposi's sarcoma-associated herpesvirus behaves similarly, but human papillomavirus does not. Contacts on the EBV side localize to OriP, the latent origin of replication. This genetic element and the EBNA1 protein that binds there are sufficient to reconstitute chromosome association preferences of the entire episome. Contacts on the human side localize to gene-poor and AT-rich regions of chromatin distant from transcription start sites. Upon reactivation from latency, however, the episome moves away from repressive heterochromatin and toward active euchromatin. Our work adds three-dimensional relocalization to the molecular events that occur during reactivation. Involvement of myriad interchromosomal associations also suggests a role for this type of long-range association in gene regulation.IMPORTANCE The human genome is structurally organized in three-dimensional space, and this structure functionally affects transcriptional activity. We set out to investigate whether a double-stranded DNA virus, Epstein-Barr virus (EBV), uses mechanisms similar to those of the human genome to regulate transcription. We found that the EBV genome associates with repressive compartments of the nucleus during latency and with active compartments during reactivation. This study advances our knowledge of the EBV life cycle, adding three-dimensional relocalization as a novel component to the molecular events that occur during reactivation. Furthermore, the data add to our understanding of nuclear compartments, showing that disperse interchromosomal interactions may be important for regulating transcription

Exchange Current Corrections to Neutrino--Nucleus Scattering

Relativistic exchange current corrections to neutrino--nucleus cross sections are presented assuming non--vanishing strange quark form factors for the constituent nucleons. For charged current processes the exchange current corrections can lower the impulse approximation results by 10\% while these corrections are found to be sensitive to both the nuclear density and the strange quark axial form factor of the nucleon for neutral current processes. Implications on the LSND experiment to determine this form factor are discussed.Comment: 11 pages, 2 figures, revtex 3.0, full postscript version of the file and figures available at http://www.nikhefk.nikhef.nl/projects/Theory/preprints/preprints.html To appear in Phys. Rev. Lett

Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation.

Congenital pulmonary airway malformation (CPAM) is the most common congenital lesion detected in the neonatal lung, which may lead to respiratory distress, infection, and pneumothorax. CPAM is thought to result from abnormal branching morphogenesis during fetal lung development, arising from different locations within the developing respiratory tract. However, the pathogenic mechanisms are unknown, and previous studies have focused on abnormalities in airway epithelial cells. We have analyzed 13 excised lung specimens from infants (age &lt; 1 year) with a confirmed diagnosis of type 2 CPAM, which is supposed to be derived from abnormal growth of intrapulmonary distal airways. By examining the mesenchymal components including smooth muscle cells, laminin, and elastin in airway and cystic walls using immunofluorescence staining, we found that the thickness and area of the smooth muscle layer underlining the airway cysts in these CPAM tissue sections were significantly decreased compared with those in bronchiolar walls of normal controls. Extracellular elastin fibers were also visually reduced or absent in airway cystic walls. In particular, a layer of elastin fibers seen in normal lung between airway epithelia and underlying smooth muscle cells was missing in type 2 CPAM samples. Thus, our data demonstrate for the first time that airway cystic lesions in type 2 CPAM occur not only in airway epithelial cells, but also in adjacent mesenchymal tissues, including airway smooth muscle cells and their extracellular protein products. This provides a new direction to study the molecular and cellular mechanisms of CPAM pathogenesis in human