Energy translation and Proper-Time Eigenstates

The usual quantum mechanics describes the mass eigenstates. To describe the proper-time eigenstates, a duality theory of the usual quantum mechanics was developed. The time interval is treated as an operator on an equal footing with the space interval, and the quantization of the space-time intervals between events is obtained. As a result, one can show that there exists a zero-point time interval.Comment: 15 pages, No figur

Clinical Features and Genetic Analysis of 20 Chinese Patients with X-Linked Hyper-IgM Syndrome

X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed the clinical and molecular features of 20 Chinese patients diagnosed and followed up in hospitals affiliated to Shanghai Jiao Tong University School of Medicine from 1999 to 2013. The median onset age of these patients was 8.5 months (range: 20 days–21 months). Half of them had positive family histories, with a shorter diagnosis lag. The most common symptoms were recurrent sinopulmonary infections (18 patients, 90%), neutropenia (14 patients, 70%), oral ulcer (13 patients, 65%), and protracted diarrhea (13 patients, 65%). Six patients had BCGitis. Six patients received hematopoietic stem cell transplantations and four of them had immune reconstructions and clinical remissions. Eighteen unique mutations in CD40L gene were identified in these 20 patients from 19 unrelated families, with 12 novel mutations. We compared with reported mutation results and used bioinformatics software to predict the effects of mutations on the target protein. These mutations reflected the heterogeneity of CD40L gene and expanded our understanding of XHIGM

Impact of Occupational Stress and Coping Styles on Burnout among Physicians in Yun Nan, China

This study was conducted to investigate the impact of occupational stress and coping styles on burnout among physicians in Yun Nan province, China. The sample consisted of 208 participants, consisting of 80 male and 128 female in-service physicians, recruited from different public hospitals. They voluntarily filled in a survey questionnaire consisting of the Occupational Stress Indicator-2 (OSI-2), the Maslach Burnout Inventory-Human Services Survey (MBI-HSS), and the Coping Inventory for Stressful Situations (CISS). The results revealed that the Chinese physicians’ reported level of occupational stress directly influenced their reported level of burnout. It was also found that the more they applied emotion-focused coping, the higher was their reported level of burnout. Their reported level of occupational stress was not found to have any significant influence on their employment of either problem-focused or avoidance-focused coping style. All three coping styles were found to be associated with burnout. The more the participants employed problem-focused coping style as well as emotion-focused style, the higher was their reported level of burnout. On the other hand, the more they employed avoidance-focused coping style the lower was their reported level of burnout