1,906 research outputs found
Is the partner of in the nonet?
Based on a mass matrix, the mixing angle of the axial vector
states and is determined to be , and the
theoretical results about the decay and production of the two states are
presented. The theoretical results are in good agreement with the present
experimental results, which suggests that can be assigned as the
partner of in the nonet. We also suggest that
the existence of needs further experimental confirmation.Comment: Latex, 6 pages, to be published in Chin. Phys. let
Tetrabenazine is neuroprotective in Huntington's disease mice
<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) is a neurodegenerative disorder caused by a polyglutamine (polyQ) expansion in Huntingtin protein (Htt). PolyQ expansion in Httexp causes selective degeneration of striatal medium spiny neurons (MSN) in HD patients. A number of previous studies suggested that dopamine signaling plays an important role in HD pathogenesis. A specific inhibitor of vesicular monoamine transporter (VMAT2) tetrabenazine (TBZ) has been recently approved by Food and Drug Administration for treatment of HD patients in the USA. TBZ acts by reducing dopaminergic input to the striatum.</p> <p>Results</p> <p>In previous studies we demonstrated that long-term feeding with TBZ (combined with L-Dopa) alleviated the motor deficits and reduced the striatal neuronal loss in the yeast artificial chromosome transgenic mouse model of HD (YAC128 mice). To further investigate a potential beneficial effects of TBZ for HD treatment, we here repeated TBZ evaluation in YAC128 mice starting TBZ treatment at 2 months of age ("early" TBZ group) and at 6 months of age ("late" TBZ group). In agreement with our previous studies, we found that both "early" and "late" TBZ treatments alleviated motor deficits and reduced striatal cell loss in YAC128 mice. In addition, we have been able to recapitulate and quantify depression-like symptoms in TBZ-treated mice, reminiscent of common side effects observed in HD patients taking TBZ.</p> <p>Conclusions</p> <p>Our results further support therapeutic value of TBZ for treatment of HD but also highlight the need to develop more specific dopamine antagonists which are less prone to side-effects.</p
Evidence of Ising pairing in superconducting NbSe atomic layers
Two-dimensional transition metal dichalcogenides with strong spin-orbit
interactions and valley-dependent Berry curvature effects have attracted
tremendous recent interests. Although novel single-particle and excitonic
phenomena related to spin-valley coupling have been extensively studied,
effects of spin-momentum locking on collective quantum phenomena remain
unexplored. Here we report an observation of superconducting monolayer NbSe
with an in-plane upper critical field over six times of the Pauli paramagnetic
limit by magneto-transport measurements. The effect can be understood in terms
of the competing Zeeman effect and large intrinsic spin-orbit interactions in
non-centrosymmetric NbSe monolayers, where the electronic spin is locked to
the out-of-plane direction. Our results provide a strong evidence of
unconventional Ising pairing protected by spin-momentum locking and open up a
new avenue for studies of non-centrosymmetric superconductivity with unique
spin and valley degrees of freedom in the exact two-dimensional limit
SGAT4PASS: Spherical Geometry-Aware Transformer for PAnoramic Semantic Segmentation
As an important and challenging problem in computer vision, PAnoramic
Semantic Segmentation (PASS) gives complete scene perception based on an
ultra-wide angle of view. Usually, prevalent PASS methods with 2D panoramic
image input focus on solving image distortions but lack consideration of the 3D
properties of original data. Therefore, their performance will
drop a lot when inputting panoramic images with the 3D disturbance. To be more
robust to 3D disturbance, we propose our Spherical Geometry-Aware Transformer
for PAnoramic Semantic Segmentation (SGAT4PASS), considering 3D spherical
geometry knowledge. Specifically, a spherical geometry-aware framework is
proposed for PASS. It includes three modules, i.e., spherical geometry-aware
image projection, spherical deformable patch embedding, and a panorama-aware
loss, which takes input images with 3D disturbance into account, adds a
spherical geometry-aware constraint on the existing deformable patch embedding,
and indicates the pixel density of original data, respectively.
Experimental results on Stanford2D3D Panoramic datasets show that SGAT4PASS
significantly improves performance and robustness, with approximately a 2%
increase in mIoU, and when small 3D disturbances occur in the data, the
stability of our performance is improved by an order of magnitude. Our code and
supplementary material are available at
https://github.com/TencentARC/SGAT4PASS.Comment: Accepted by IJCAI 202
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