146 research outputs found
Long-Horizon Dialogue Understanding for Role Identification in the Game of Avalon with Large Language Models
Deception and persuasion play a critical role in long-horizon dialogues
between multiple parties, especially when the interests, goals, and motivations
of the participants are not aligned. Such complex tasks pose challenges for
current Large Language Models (LLM) as deception and persuasion can easily
mislead them, especially in long-horizon multi-party dialogues. To this end, we
explore the game of Avalon: The Resistance, a social deduction game in which
players must determine each other's hidden identities to complete their team's
objective. We introduce an online testbed and a dataset containing 20 carefully
collected and labeled games among human players that exhibit long-horizon
deception in a cooperative-competitive setting. We discuss the capabilities of
LLMs to utilize deceptive long-horizon conversations between six human players
to determine each player's goal and motivation. Particularly, we discuss the
multimodal integration of the chat between the players and the game's state
that grounds the conversation, providing further insights into the true player
identities. We find that even current state-of-the-art LLMs do not reach human
performance, making our dataset a compelling benchmark to investigate the
decision-making and language-processing capabilities of LLMs. Our dataset and
online testbed can be found at our project website:
https://sstepput.github.io/Avalon-NLU/Comment: Accepted to the 2023 Conference on Empirical Methods in Natural
Language Processing (EMNLP, Findings of the Association for Computational
Linguistics
Case Report: Identification of a novel LYN::LINC01900 transcript with promyelocytic phenotype and TP53 mutation in acute myeloid leukemia
Acute myeloid leukemia (AML) is a malignant disease of myeloid hematopoietic stem/progenitor cells characterized by the abnormal proliferation of primitive and naive random cells in the bone marrow and peripheral blood. Acute promyelocytic leukemia (APL) is a type (AML-M3) of AML. Most patients with APL have the characteristic chromosomal translocation t(15; 17)(q22; q12), forming PML::RARA fusion. The occurrence and progression of AML are often accompanied by the emergence of gene fusions such as PML::RARA, CBFβ::MYH11, and RUNX1::RUNX1T1, among others. Gene fusions are the main molecular biological abnormalities in acute leukemia, and all fusion genes act as crucial oncogenic factors in leukemia. Herein, we report the first case of LYN::LINC01900 fusion transcript in AML with a promyelocytic phenotype and TP53 mutation. Further studies should address whether new protein products may result from this fusion, as well as the biological function of these new products in disease occurrence and progression
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