2,876 research outputs found

    A nondiagrammatic calculation of the Rho parameter from heavy fermions

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    A simple nondiagrammatic evaluation of the nondecoupling effect of heavy fermions on the Veltman's Rho parameter is presented in detail. This calculation is based on the path integral approach, the electroweak chiral Lagrangian formalism, and the Schwinger proper time method.Comment: 11 page

    Fatigue improvement of rib-to-deck welded joints using adhesively bonded steel patches - LEFM-based parametric study

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    Rib-to-deck welded joints in orthotropic steel decks of bridges are prone to develop fatigue cracks. Repairing such cracks allows for prolonging the life of the infrastructure, provided that structural safety is guaranteed. Among others, the repair technique of adhesively bonded steel patches is relatively simple and inexpensive. Moreover, it has the advantage that the original structure is not altered, e.g. as in the case of crack stop holes. This technique has been used in other details like the diaphragm of steel bridges. However, limited information is available when applied to rib-to-deck joints, which are the most common joint type in orthotropic steel decks. This study proposes two repair schemes using adhesively bonded steel patches for the rib-to-deck joints. A 3-D finite element model which takes account of the crack size is established. Based on linear elastic fracture mechanics (LEFM), a parametric study is performed to investigate the effect of patch geometry and adhesive thickness on the performance of repair schemes

    A Comparative Study of Segmentation Algorithms in the Classification of Human Skin Burn Depth

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    A correct first assessment of a skin burn depth is essential as it determines a correct first burn treatment provided to the patients. The objective of this paper is to conduct a comparative study of the different segmentation algorithms for the classification of different burn depths. Eight different hybrid segmentation algorithms were studied on a skin burn dataset comprising skin burn images categorized into three burn classes by medical experts; superficial partial thickness burn (SPTB), deep partial thickness burn (DPTB) and full thickness burn (FTB). Different sequences of the algorithm were experimented as each algorithm was able to segment differently, leading to different segmentation in the final output. The performance of the segmentation algorithms was evaluated by calculating the number of correctly segmented images for each burn depth. The empirical results showed that the segmentation algorithm that was able to segment most of the burn depths had achieved 40.24%, 60.42% and 6.25% of correctly segmented image for SPTB, DPTB and FTB respectively. Most of the segmentation algorithms could not segment well for FTB images because of the different nature of the burn wounds as some of the FTB images contained dark brown and black colors. It can be concluded that a good segmentation algorithm is required to ensure that the representative features of each burn depth can be extracted to contribute to higher accuracy of classification of skin burn depth

    Presacral Teratocarcinoma Presenting as Anal Fistula and Rectal Adenocarcinoma: A Unique Case Presentation and Literature Review

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    Somatic malignancy arising from presacral or retroperitoneal primary teratoma is extremely rare. We report the case of a 37-year-old male patient with adenocarcinoma of respiratory type arising from primary presacral teratoma, but which first presented as anal fistula and rectal adenocarcinoma. The two tumors show the same morphology and immunophenotype (CK7–CK20+CDx2+). Malignant adenocarcinoma transformations from the normal respiratory epithelium are also found. To the best of our knowledge, this is the second case of respiratory type adenocarcinoma arising from primary presacral mature cystic teratoma

    Spatiotemporal control of root immune responses during microbial colonization.

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    The entire evolutionary trajectory of plants towards large and complex multi-cellular organisms has been accompanied by incessant interactions with omnipresent unicellular microbes. This led to the evolution of highly complex microbial communities, whose members display the entire spectrum of pathogenic to mutualistic behaviors. Plant roots are dynamic, fractally growing organs and even small Arabidopsis roots harbor millions of individual microbes of diverse taxa. It is evident that microbes at different positions on a root surface could experience fundamentally different environments, which, moreover, rapidly change over time. Differences in spatial scales between microbes and roots compares to humans and the cities they inhabit. Such considerations make it evident that mechanisms of root-microbe interactions can only be understood if analyzed at relevant spatial and temporal scales. This review attempts to provide an overview of the rapid recent progress that has been made in mapping and manipulating plant damage and immune responses at cellular resolution, as well as in visualizing bacterial communities and their transcriptional activities. We further discuss the impact that such approaches will have for a more predictive understanding of root-microbe interactions

    Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3

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    Background: We have previously confirmed the importance of rat chromosome 3 (RNO3) genetic loci on blood pressure elevation, pulse pressure (PP) variability and renal pathology during salt challenge in the stroke-prone spontaneously hypertensive (SHRSP) rat. The aims of this study were to generate a panel of RNO3 congenic sub-strains to genetically dissect the implicated loci and identify positional candidate genes by microarray expression profiling and analysis of next-generation sequencing data. Method and results: A panel of congenic sub-strains were generated containing Wistar-Kyoto (WKY)-introgressed segments of varying size on the SHRSP genetic background, focused within the first 50 Mbp of RNO3. Haemodynamic profiling during salt challenge demonstrated significantly reduced systolic blood pressure, diastolic blood pressure and PP variability in SP.WKYGla3a, SP.WKYGla3c, SP.WKYGla3d and SP.WKYGla3e sub-strains. Only SBP and DBP were significantly reduced during salt challenge in SP.WKYGla3b and SP.WKYGla3f sub-strains, whereas SP.WKYGla3g rats did not differ in haemodynamic response to SHRSP. Those sub-strains demonstrating significantly reduced PP variability during salt challenge also demonstrated significantly reduced renal pathology and proteinuria. Microarray expression profiling prioritized two candidate genes for blood pressure regulation (Dnm1, Tor1b), localized within the common congenic interval shared by SP.WKYGla3d and SP.WKYGla3f strains, and one candidate gene for salt-induced PP variability and renal pathology (Rabgap1), located within the region unique to the SP.WKYGla3d strain. Comparison of next-generation sequencing data identified variants within additional positional genes that are likely to affect protein function. Conclusion: This study has identified distinct intervals on RNO3-containing genes that may be important for blood pressure regulation and renal pathology during salt challenge

    Two dimensional scaling of resistance in flux flow region in Tl2Ba2CaCu2O8Tl_2Ba_2CaCu_2O_8 thin films

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    The resistance of Tl2Ba2CaCu2O8Tl_2Ba_2CaCu_2O_8 thin films has been measured when the angle between the applied fields and abab-plane of the film is changed continuously at various temperatures. Under various magnetic fields, the resistance can be well scaled in terms of the c-axis component of the applied fields at the same temperature in the whole angle range. Meanwhile, we show that the measurement of resistance in this way is a complementary method to determine the growth orientation of the anisotropic high-TcT_c superconductors.Comment: 11 pages, 8 figures. Have been published in Physica

    Portable C/C++ code for portable XML data

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