Adaptive Fault Diagnosis of Motors Using Comprehensive Learning Particle Swarm Optimizer with Fuzzy Petri Net

This study proposes and applies a comprehensive learning particle swarm optimization (CLPSO) fuzzy Petri net (FPN) algorithm, which is based on the CLPSO algorithm and FPN, to the fault diagnosis of a complex motor. First, the transition confidence is replaced by a Gaussian function to deal with the uncertainty of fault propagation. Then, according to the Petri net principle, a competition operator is introduced to improve the matrix reasoning. Finally, a CLPSO-FPN model for motor fault diagnosis is established based on the motor failure mechanism and fault characteristics. The CLPSO algorithm is used to generate the system parameters for fault diagnosis and to improve the adaptability and accuracy of fault diagnosis. This study considers the example of a three-phase asynchronous motor. The results show that the proposed algorithm can diagnose faults in this motor with satisfactory adaptability and accuracy compared with the traditional FPN algorithm. By establishing the system model, the fault propagation process of motors can be accurately and intuitively expressed, thus improving the fault treatment and equipment maintenance of motors

Ultrasound-targeted microbubble destruction mediated herpes simplex virus-thymidine kinase gene treats hepatoma in mice

<p>Abstract</p> <p>Objective</p> <p>The purpose of the study was to explore the anti-tumor effect of ultrasound -targeted microbubble destruction mediated herpes simplex virus thymidine kinase (HSV-TK) suicide gene system on mice hepatoma.</p> <p>Methods</p> <p>Forty mice were randomly divided into four groups after the models of subcutaneous transplantation tumors were estabilished: (1) PBS; (2) HSV-TK (3) HSV-TK+ ultrasound (HSV-TK+US); (4) HSV-TK+ultrasound+microbubbles (HSV-TK+US+MB). The TK protein expression in liver cancer was detected by western-blot. Applying TUNEL staining detected tumor cell apoptosis. At last, the inhibition rates and survival time of the animals were compared among all groups.</p> <p>Results</p> <p>The TK protein expression of HSV-TK+MB+US group in tumor-bearing mice tissues were significantly higher than those in other groups. The tumor inhibitory effect of ultrasound-targeted microbubble destruction mediated HSV-TK on mice transplantable tumor was significantly higher than those in other groups (p < 0.05), and can significantly improve the survival time of tumor-bearing mice.</p> <p>Conclusion</p> <p>Ultrasound-targeted microbubble destruction can effectively transfect HSV-TK gene into target tissues and play a significant inhibition effect on tumors, which provides a new strategy for gene therapy in liver cancer.</p

Are We Ready to Embrace Generative AI for Software Q&A?

Stack Overflow, the world's largest software Q&A (SQA) website, is facing a significant traffic drop due to the emergence of generative AI techniques. ChatGPT is banned by Stack Overflow after only 6 days from its release. The main reason provided by the official Stack Overflow is that the answers generated by ChatGPT are of low quality. To verify this, we conduct a comparative evaluation of human-written and ChatGPT-generated answers. Our methodology employs both automatic comparison and a manual study. Our results suggest that human-written and ChatGPT-generated answers are semantically similar, however, human-written answers outperform ChatGPT-generated ones consistently across multiple aspects, specifically by 10% on the overall score. We release the data, analysis scripts, and detailed results at https://anonymous.4open.science/r/GAI4SQA-FD5C.Comment: Accepted by the New Ideas and Emerging Results (NIER) track at The IEEE/ACM Automated Software Engineering (ASE) Conferenc