280,182 research outputs found

    Measuring forces between protein fibers by microscopy

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    We propose a general scheme for measuring the attraction between mechanically frustrated semiflexible fibers by measuring their thermal fluctuations and shape. We apply this analysis to a system of sickle hemoglobin (HbS) fibers that laterally attract one another. These fibers appear to “zip” together before reaching mechanical equilibrium due to the existence of cross-links into a dilute fiber network. We are also able to estimate the rigidities of the fibers. These rigidities are found to be consistent with sickle hemoglobin “single” fibers 20 nm in diameter, despite recent experiments indicating that fiber bundling sometimes occurs. Our estimate of the magnitude of the interfiber attraction for HbS fibers is in the range 8 ± 7 kBT/μm, or 4 ± 3 kBT/μm if the fibers are assumed, a priori to be single fibers (such an assumption is fully consistent with the data). This value is sufficient to bind the fibers, overcoming entropic effects, although extremely chemically weak. Our results are compared to models for the interfiber attraction that include depletion and van der Waals forces. This technique should also facilitate a similar analysis of other filamentous protein assembles in the future, including β-amyloid, actin, and tubulin

    Helium star evolutionary channel to super-Chandrasekhar mass type Ia supernovae

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    Recent discovery of several overluminous type Ia supernovae (SNe Ia) indicates that the explosive masses of white dwarfs may significantly exceed the canonical Chandrasekhar mass limit. Rapid differential rotation may support these massive white dwarfs. Based on the single-degenerate scenario, and assuming that the white dwarfs would differentially rotate when the accretion rate M˙>3×107Myr1\dot{M}>3\times 10^{-7}M_{\odot}\rm yr^{-1}, employing Eggleton's stellar evolution code we have performed the numerical calculations for \sim 1000 binary systems consisting of a He star and a CO white dwarf (WD). We present the initial parameters in the orbital period - helium star mass plane (for WD masses of 1.0M1.0 M_{\odot} and 1.2M1.2 M_{\odot}, respectively), which lead to super-Chandrasekhar mass SNe Ia. Our results indicate that, for an initial massive WD of 1.2M1.2 M_{\odot}, a large number of SNe Ia may result from super-Chandrasekhar mass WDs, and the highest mass of the WD at the moment of SNe Ia explosion is 1.81 MM_\odot, but very massive (>1.85M>1.85M_{\odot}) WDs cannot be formed. However, when the initial mass of WDs is 1.0M1.0 M_{\odot}, the explosive masses of SNe Ia are nearly uniform, which is consistent with the rareness of super-Chandrasekhar mass SNe Ia in observations.Comment: 6 pages, 7 figures, accepted for publication in Astronomy and Astrophysic

    The NJL model and strange quark matter

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    The stability of strange quark matter is studied within the Nambu Jona-Lasinio model with three different parameter sets. The model Lagrangian contains 4-fermion (with and without vector interaction) and 6-fermion terms; the minimum energy per baryon number as a function of the strangeness fraction of the system is compared to the masses of hyperons having the same strangeness fraction, and coherently calculated in the same version of the model, and for the same parameter set. The results show that in none of the different parameter sets strangelets are stable, and in some cases a minimum in the energy per baryon does not even exist.Comment: 8 pages, 2 figures, reference added, typos corrected, version to appear in Europhys. Let

    A comparative analysis of the value of information in a continuous time market model with partial information: the cases of log-utility and CRRA

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    We study the question what value an agent in a generalized Black-Scholes model with partial information attributes to the complementary information. To do this, we study the utility maximization problems from terminal wealth for the two cases partial information and full information. We assume that the drift term of the risky asset is a dynamic process of general linear type and that the two levels of observation correspond to whether this drift term is observable or not. Applying methods from stochastic filtering theory we derive an analytical tractable formula for the value of information in the case of logarithmic utility. For the case of constant relative risk aversion (CRRA) we derive a semianalytical formula, which uses as an input the numerical solution of a system of ODEs. For both cases we present a comparative analysis
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