"The Best of Times and the Worst of Times"

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67305/2/10.1177_00220345870660070201.pd

The 50th Anniversary of Water Fluoridation in Grand Rapids, Michigan

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66261/1/j.1752-7325.1996.tb02443.x.pd

Antimicrobials in Dentistry: With Knowledge Comes Responsibility

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67020/2/10.1177_00220345960750070101.pd

Inhibition of Acid Production from Oral Bacteria by Fluorapatite-derived Fluoride

The inhibitory effect of fluorapatite (FAP)-derived fluoride upon resting cell suspensions of Streptococcus mutans incubated at pH 4.5 and 6.5 was studied using lactic acid production from 0.1% sucrose as an indicator of fermentation activity. Cells incubated with FAP produced significantly less lactic acid than did cells incubated with hydroxyapatite (HAP). Addition of HAP to cell suspensions containing FAP reduced this inhibition, suggesting that dissolution of the FAP was necessary for inhibition. Incubation with low concentrations of NaF showed significant inhibition in cell suspensions incubated with as little as 0.45 μg/mL F at pH 5.0. These results provide further support to the hypothesis that fluoride levels in plaque and enamel, achievable through use of fluoridated water and/or fluoride dentifrices, may produce appreciable inhibition of glycolysis at the acidic pH levels which are readily achieved in plaque. Thus, bacterial acid production may activate plaque and enamel-bound fluoride, resulting in inhibition of further acid production, and thereby contribute substantially to the other cariostatic mechanisms of fluoride.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66960/2/10.1177_00220345860650010401.pd

The prevalence of BANA‐hydrolyzing periodontopathic bacteria in smokers

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99012/1/j.1600-051X.1999.tb02526.x.pd

Intraoral Transmission of Streptococcus mutans by a Dental Explorer

A streptomycin-resistant strain of S. mutans was introduced into the mouth as adherent growth on an artificial fissure (AF). A second AF, which was initially sterile, was placed in a crown on the opposite side of the dentition. The labeled strain was not found in 8 initially-sterile AFs which were left in vivo for 2 to 6 days and were not examined with a dental explorer. The labeled strain was detected in 7 of 9 initially-sterile AFs which were probed with the dental explorer.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67969/2/10.1177_00220345790580080201.pd

The Effects of Incubation Length and Temperature on the Specificity and Sensitivity of the BANA (N‐Benzoyl‐DL‐Arginine‐Naphthylamide) Test

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141244/1/jper0848.pd