Factors Impacting Clinical And Counseling Psychology Students Conducting Research With Lgbt Populations

Although a large body of literature exists on training clinical and counseling psychology researchers, scant empirical work has been published that looks at the unique needs of students working with lesbian, gay, bisexual, and transgender (LGBT) populations. This study explores researcher development experiences of those students. Two hypotheses are tested with a sample of 59 doctoral students in APA-accredited clinical and counseling psychology program. The first hypothesis posits that Exploration and Commitment Factors of the Measure of Sexual Identity Exploration and Commitment (MoSIEC) will account for variance on the Research Outcome Expectations Questionnaire (ROEQ) beyond that accounted for by social cognitive variables such as Research Self Efficacy, Research Training Environment, and Psychosocial Research Mentoring. This hypothesis was partially supported. A hierarchical multiple regression demonstrated that although the Exploration Factor of the MoSIEC accounted for a significant amount of variance beyond social cognitive factors, the Commitment factor did not. The second hypothesis - that students identifying as LGB would score higher on the Psychosocial Factor of the Research Mentorship Experiences Scale - did not result in significant findings. Post-hoc analyses explored differences between four groups of participants: heterosexual and non-heterosexual participants, clinical psychology students and counseling psychology students, students with and without records of publication or presentation of LGBT-research, and students who had passed comprehensive exams and those who had not. Results and implications for training doctoral students in clinical and counseling psychology who conduct research with LGBT populations are discussed

Limitations of the Perioperative Cardiovascular Evaluation for Assessing Coronary Artery Disease: A Case Report

INTRODUCTION The American College of Cardiology (ACC) and the American Heart Association (AHA) publ ished pre-operative risk stratification guidelines in 2014. These guidelines have routinely been used by physicians to pre-operatively risk stratify patients. In this case report, a patient was found to have multi-vessel coronary artery disease post-operatively in the setting of unremarkable cardiac work-up preoperatively. This case highlights a limitation of the 2014 ACC/AHA guidelines

Distribution and origin of organic matter preserved in modern surface sediments throughout Coastal SE Alaska

Twenty seven modern (top 1-2cm) sediment samples from multicores retrieved from throughout coastal SE Alaska were analyzed for their organic matter content and the source composition. Total organic carbon (TOC) as well as biogenic silica (bioSi), and calcium carbonate (CaCO3) content were analyzed to evaluate the organic matter content and its context with respect to total sediment mass. Terrestrial and marine contribution to TOC content was assessed from interpretation of the spatial distribution of elemental (C/N), stable isotopic (13C, 15N) and a variety of lipid biomarker measurements. Results showed that TOC was highly enriched in the region of the study area south of 58oN off the coast of the Queen Charlotte and Baranof Islands. TOC was highly correlated with bioSi content (r = +0.98), indicating that the majority of the TOC originates from diatom production in this area. C/N, 13C and 15N results indicated higher terrestrial contribution to TOC deposited north of 58°N and higher marine contribution to the south. Lipid biomarkers of marine origin, such as long chain (C37-39) alkenones and highly branched isoprenoid (HBI) C25 and C30 hydrocarbons, were most enriched in the sediments south of 58°N, consistent with results from bulk analyses. However, brassicasterol and dinosterol, two sterols indicative of diatoms and dinoflagellates, respectively, displayed no recognizable spatial pattern. Concentrations for homologous series of long chain (>C20) n-alkanes, n-alcohols and n-acids of terrestrial origin were distributed in a pattern largely counter to that of the bulk analyses. Long chain n-alkane signatures isolated from northern sediments were not typical of higher plants but rather displayed a lack of odd carbon number predominance. Those in southern sediments were typical of higher plants and accompanied by a major relative amount of the pentacyclic triterpene, 17β(H),21β(H)-hop-22(29)-ene (diploptene). These biomarker observations suggest that the terrestrial component of TOC deposited in sediments north of 58oN is fossil organic matter associated with glacial outwash of major rivers in that area, while that in sediments depositing to the south is derived from more modern soil erosion processes

Career Decision Self‐Efficacy of Transgender People: Pre‐ and Posttransition

Although the mental health needs of transgender and gender‐nonconforming (TGNC) people have recently been addressed more directly than in the past (Bockting, Miner, Swinburne Romine, Hamilton, & Coleman, 2013; dickey, Reisner, & Juntunen, 2015; Meier, Pardo, Labuski, & Babcock, 2013), there remains a dearth of information related to vocational development of this population. Some of the considerations in career counseling and vocational development among TGNC people include differences in developmental concerns related to gender transition, gender presentation, passing (e.g., being perceived by others in one\u27s affirmed gender), and binary and fluid gender identities (Beemyn & Rankin, 2011; Harrison, Grant, & Herman, 2012). In the present study, we consider gender transition with regard to career decision self‐efficacy (CDSE) among TGNC people pre‐ and posttransition

Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy.

The most common cause of dilated cardiomyopathy and heart failure (HF) is ischemic heart disease; however, in a third of all patients the cause remains undefined and patients are diagnosed as having idiopathic dilated cardiomyopathy (IDC). Recent studies suggest that many patients with IDC have a family history of HF and rare genetic variants in over 35 genes have been shown to be causative of disease. We employed whole-exome sequencing to identify the causative variant in a large family with autosomal dominant transmission of dilated cardiomyopathy. Sequencing and subsequent informatics revealed a novel 10-nucleotide deletion in the BCL2-associated athanogene 3 (BAG3) gene (Ch10:del 121436332_12143641: del. 1266_1275 [NM 004281]) that segregated with all affected individuals. The deletion predicted a shift in the reading frame with the resultant deletion of 135 amino acids from the C-terminal end of the protein. Consistent with genetic variants in genes encoding other sarcomeric proteins there was a considerable amount of genetic heterogeneity in the affected family members. Interestingly, we also found that the levels of BAG3 protein were significantly reduced in the hearts from unrelated patients with end-stage HF undergoing cardiac transplantation when compared with non-failing controls. Diminished levels of BAG3 protein may be associated with both familial and non-familial forms of dilated cardiomyopathy