313 research outputs found

    A new approach to feature extraction for RNA structure comparision

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    In recent years, RNA structural comparison becomes a crucial problem in bioinformatics research. Generally, it is a popular approach for representing the RNA secondary structures with arc-annotation sets. Several methods can be used to compare two RNA structures, such as tree edit distance, longest arc-preserving common subsequence (LAPCS) and stem based alignment. However, these methods may be helpful only for small RNA structures because of their high time complexity. In this thesis, we propose a simplified method to compare two RNA structures in O(mn) time, where m and n are the lengths of the two RNA sequences, respectively. The method transforms the RNA structures into specific sequences called object sequences, then compare these object sequences to find their common substructures. The comparison method is tested with 118 RNA structures obtained from RNase P Database. For any two structures, it is important to identify whether they are in the same family by both structure comparison and sequence comparison. In the experiment, it is found that the method for comparing RNA structures can yield better hit rates and is faster than the traditional method to compare the RNA sequences. Therefore, the approach to extract and compare the RNA secondary structures is more sensitive in biology and more efficient in time complexity

    Basic Treatment of QCD Phase Transition Bubble Nucleation

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    Starting from the QCD Lagrangian and the surface tension of QCD bubbles we derive the critical size of bubbles, the nucleation probability and the nucleation site separation distance. We find the separation of sites is more than an order of magnitude larger than previous QCD model estimates, which could lead to observable effects.Comment: 8 pages, one figur

    Emergency Rescue: Helping hands for people in city

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    This paper is for public help in critical situation like accident, robbery or any fire accident. In this project, the main motto is to help the people in city through android application. Recent working of systems like police station, hospitals and fire brigade is manual. Through this developed website and android application this system may change to online service. For this user will click photograph from application and send it to nearest system which he required that is either police station or fire brigade or hospital. As while sending photograph the current location of user as well as date and time will also be sent to the particular systems, they does not require much efforts to search those places on map or to ask someone else for enquiry. As system will also have an account on android application so their efforts are again reduced. Not only the whole route but also the shortest route among those routes will be displayed on application screen

    Online Ensemble Model Compression using Knowledge Distillation

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    This paper presents a novel knowledge distillation based model compression framework consisting of a student ensemble. It enables distillation of simultaneously learnt ensemble knowledge onto each of the compressed student models. Each model learns unique representations from the data distribution due to its distinct architecture. This helps the ensemble generalize better by combining every model's knowledge. The distilled students and ensemble teacher are trained simultaneously without requiring any pretrained weights. Moreover, our proposed method can deliver multi-compressed students with single training, which is efficient and flexible for different scenarios. We provide comprehensive experiments using state-of-the-art classification models to validate our framework's effectiveness. Notably, using our framework a 97% compressed ResNet110 student model managed to produce a 10.64% relative accuracy gain over its individual baseline training on CIFAR100 dataset. Similarly a 95% compressed DenseNet-BC(k=12) model managed a 8.17% relative accuracy gain

    Extended metal-organic solids based on benzenepolycarboxylic and aminobenzoic acids

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    This article describes the recent results obtained in our laboratory on the interaction of polyfunctional ligands with divalent alkaline earth metal ions and a few divalent transition metal ions. Treatment of MC12·nH2O (M = Mg, Ca, Sr or Ba) with 2-amino benzoic acid leads to the formation of complexes [Mg(2-aba)2] (1), [Ca(2-aba)2(OH2)3]∞ (2), [{Sr(2-aba)2(OH2)2}2·H2O)]∞ (3), [Ba(2-aba)2(OH2)]∞ (4), respectively. While the calcium ions in 2 are hepta-coordinated, the strontium and barium ions in 3 and 4 reveal a coordination number of nine apart from additional metal-metal interactions. Apart from the carboxylate functionality, the amino group also binds to the metal centres in the case of strontium and barium complexes 3 and 4. Complexes [{Mg(H2O)6}(4-aba)2·2H2O] (5), [Ca(4-aba)2(H2O)2] (6) prepared from 4-aminobenzoic acid reveal more open or layered structures. Interaction of 2-mercaptobenzoic acid with MCl2·6H2O (M = Mg, Ca), however, leads to the oxidation of the thiol group resulting in the disulphide 2,2' -dithiobis(benzoic acid). New metal-organic framework based hydrogen-bonded porous solids [{M(btec) (OH2)4}n·n(C4H12N2)·4nH2O] (btec = 1,2,4,5-benzene tetracarboxylate) (M = Co9; Ni10; Zn11) have been synthesized from 1,2,4,5-benzene tetracarboxylic acid in the presence of piperazine. These compounds are made up of extensively hydrogen-bonded alternating layers of anionic M-btec co-ordination polymer and piperazinium cations. Compounds 2- 11 described herein form polymeric networks in the solid-state with the aid of different coordinating capabilities of the carboxylate anions hydrogen bonding interactions

    Tail-to-tail carbon-carbon bond coupling of acetylides on chalcogen-bridged Fe/W mixed-metal clusters

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    On thermolysis of a toluene solution containing [Fe3(CO)9(μ3-E)2] (E = S 1a, Se 16 or Te 1c) and [W(η5-C5Me5)2(CO)3(C≡CPh)]2 the new clusters [W2Fe3(η5-C5Me5)2(CO)6(μ3-E)2{μ4-CC(Ph)C(Ph)C}] (E = S 3, Se 4 or Te 5) were isolated. Compounds 3-5 were characterised by IR and 1H, 13C, 77Se and 125Te NMR spectroscopy. The crystal structure of 3 was elucidated by X-ray diffraction methods. It shows a novel tail-to-tail coupling of substituted acetylides on a sulfur-bridged mixed-metal Fe-W cluster
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